Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes.
RéversibilitéGestion des complications
Facteurs de risque
5
#1
Quels sont les facteurs de risque pour les anomalies des motifs EF Hands ?
Les facteurs incluent des prédispositions génétiques et des expositions environnementales.
Facteurs de risquePrédispositions génétiques
#2
L'âge influence-t-il les motifs EF Hands ?
Oui, le vieillissement peut affecter la fonction des motifs EF Hands et la signalisation calcique.
ÂgeVieillissement
#3
Le mode de vie joue-t-il un rôle dans les risques ?
Un mode de vie sédentaire et une mauvaise alimentation augmentent les risques.
Mode de vieAlimentation
#4
Les antécédents familiaux sont-ils un facteur de risque ?
Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque.
Antécédents familiauxMaladies génétiques
#5
Les infections peuvent-elles affecter les motifs EF Hands ?
Certaines infections peuvent perturber la signalisation calcique, affectant ces motifs.
InfectionsSignalisation calcique
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Motifs EF Hands : Questions médicales les plus fréquentes",
"headline": "Motifs EF Hands : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Motifs EF Hands : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-03-19",
"dateModified": "2025-03-14",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Motifs EF Hands"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Motifs à hélice-boucle-hélice",
"url": "https://questionsmedicales.fr/mesh/D018257",
"about": {
"@type": "MedicalCondition",
"name": "Motifs à hélice-boucle-hélice",
"code": {
"@type": "MedicalCode",
"code": "D018257",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "G02.111.570.820.709.275.500.360"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Motifs EF Hands",
"alternateName": "EF Hand Motifs",
"code": {
"@type": "MedicalCode",
"code": "D020832",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Peter B Stathopulos",
"url": "https://questionsmedicales.fr/author/Peter%20B%20Stathopulos",
"affiliation": {
"@type": "Organization",
"name": "Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada."
}
},
{
"@type": "Person",
"name": "Qi-Tong Lin",
"url": "https://questionsmedicales.fr/author/Qi-Tong%20Lin",
"affiliation": {
"@type": "Organization",
"name": "Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada."
}
},
{
"@type": "Person",
"name": "Biraj B Kayastha",
"url": "https://questionsmedicales.fr/author/Biraj%20B%20Kayastha",
"affiliation": {
"@type": "Organization",
"name": "Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA."
}
},
{
"@type": "Person",
"name": "Aya Kubo",
"url": "https://questionsmedicales.fr/author/Aya%20Kubo",
"affiliation": {
"@type": "Organization",
"name": "Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA."
}
},
{
"@type": "Person",
"name": "Jacob Burch-Konda",
"url": "https://questionsmedicales.fr/author/Jacob%20Burch-Konda",
"affiliation": {
"@type": "Organization",
"name": "Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "A case-control study of infections caused by",
"datePublished": "2022-07-28",
"url": "https://questionsmedicales.fr/article/35967868",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3389/fcimb.2022.867347"
}
},
{
"@type": "ScholarlyArticle",
"name": "Errors in Surgery: A Case Control Study.",
"datePublished": "2022-08-10",
"url": "https://questionsmedicales.fr/article/35946794",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/SLA.0000000000005664"
}
},
{
"@type": "ScholarlyArticle",
"name": "Iron status in women with infertility and controls: a case-control study.",
"datePublished": "2023-06-08",
"url": "https://questionsmedicales.fr/article/37361544",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3389/fendo.2023.1173100"
}
},
{
"@type": "ScholarlyArticle",
"name": "Sleeve Gastrectomy in Septuagenarians: a Case-Control Study.",
"datePublished": "2022-07-05",
"url": "https://questionsmedicales.fr/article/35788952",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s11695-022-06193-8"
}
},
{
"@type": "ScholarlyArticle",
"name": "Diverticulitis Familiality: A Statewide Case-Control Study.",
"datePublished": "2023-07-05",
"url": "https://questionsmedicales.fr/article/37403933",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1097/XCS.0000000000000799"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Phénomènes chimiques",
"item": "https://questionsmedicales.fr/mesh/D055598"
},
{
"@type": "ListItem",
"position": 3,
"name": "Phénomènes biochimiques",
"item": "https://questionsmedicales.fr/mesh/D001669"
},
{
"@type": "ListItem",
"position": 4,
"name": "Conformation moléculaire",
"item": "https://questionsmedicales.fr/mesh/D008968"
},
{
"@type": "ListItem",
"position": 5,
"name": "Conformation des protéines",
"item": "https://questionsmedicales.fr/mesh/D011487"
},
{
"@type": "ListItem",
"position": 6,
"name": "Éléments structuraux des protéines",
"item": "https://questionsmedicales.fr/mesh/D000072416"
},
{
"@type": "ListItem",
"position": 7,
"name": "Motifs à hélice-boucle-hélice",
"item": "https://questionsmedicales.fr/mesh/D018257"
},
{
"@type": "ListItem",
"position": 8,
"name": "Motifs EF Hands",
"item": "https://questionsmedicales.fr/mesh/D020832"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Motifs EF Hands - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Motifs EF Hands",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-09",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Motifs EF Hands",
"description": "Comment diagnostiquer un motif EF Hand ?\nQuels tests sont utilisés pour les motifs EF Hands ?\nLes motifs EF Hands sont-ils visibles par imagerie ?\nPeut-on identifier des mutations dans les motifs EF Hands ?\nQuel rôle joue la bioinformatique dans le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Motifs EF Hands",
"description": "Quels symptômes sont associés aux motifs EF Hands ?\nLes motifs EF Hands sont-ils liés à des maladies ?\nComment les motifs EF Hands affectent-ils la signalisation cellulaire ?\nY a-t-il des signes cliniques de dysfonction des motifs EF Hands ?\nLes motifs EF Hands influencent-ils le métabolisme ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Motifs EF Hands",
"description": "Peut-on prévenir les anomalies des motifs EF Hands ?\nY a-t-il des facteurs environnementaux à considérer ?\nComment le stress influence-t-il les motifs EF Hands ?\nL'exercice physique a-t-il un impact sur ces motifs ?\nLes suppléments de calcium sont-ils bénéfiques ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Motifs EF Hands",
"description": "Quels traitements ciblent les motifs EF Hands ?\nPeut-on modifier les motifs EF Hands par thérapie génique ?\nLes médicaments peuvent-ils influencer les motifs EF Hands ?\nY a-t-il des approches expérimentales pour traiter les anomalies ?\nComment la nutrition peut-elle influencer les motifs EF Hands ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Motifs EF Hands",
"description": "Quelles complications peuvent survenir avec des motifs EF Hands défectueux ?\nLes motifs EF Hands sont-ils liés à des cancers ?\nComment les complications affectent-elles la qualité de vie ?\nY a-t-il des risques de maladies cardiovasculaires ?\nLes complications sont-elles réversibles ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Motifs EF Hands",
"description": "Quels sont les facteurs de risque pour les anomalies des motifs EF Hands ?\nL'âge influence-t-il les motifs EF Hands ?\nLe mode de vie joue-t-il un rôle dans les risques ?\nLes antécédents familiaux sont-ils un facteur de risque ?\nLes infections peuvent-elles affecter les motifs EF Hands ?",
"url": "https://questionsmedicales.fr/mesh/D020832?mesh_terms=Case-Control+Studies#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer un motif EF Hand ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur des analyses biochimiques et des études de structure protéique."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour les motifs EF Hands ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la spectroscopie RMN et la cristallographie aux rayons X sont utilisées."
}
},
{
"@type": "Question",
"name": "Les motifs EF Hands sont-ils visibles par imagerie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, ils nécessitent des méthodes biochimiques pour être étudiés, pas d'imagerie classique."
}
},
{
"@type": "Question",
"name": "Peut-on identifier des mutations dans les motifs EF Hands ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des techniques de séquençage génétique peuvent révéler des mutations affectant ces motifs."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la bioinformatique dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "La bioinformatique aide à prédire la structure et la fonction des motifs EF Hands."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés aux motifs EF Hands ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les motifs EF Hands ne présentent pas de symptômes directs, mais affectent des fonctions cellulaires."
}
},
{
"@type": "Question",
"name": "Les motifs EF Hands sont-ils liés à des maladies ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans ces motifs peuvent être associées à des maladies comme l'ataxie."
}
},
{
"@type": "Question",
"name": "Comment les motifs EF Hands affectent-ils la signalisation cellulaire ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils régulent la signalisation calcique, influençant divers processus cellulaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques de dysfonction des motifs EF Hands ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes indirects peuvent apparaître, comme des troubles neurologiques ou musculaires."
}
},
{
"@type": "Question",
"name": "Les motifs EF Hands influencent-ils le métabolisme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils jouent un rôle dans le métabolisme cellulaire en régulant le calcium."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies des motifs EF Hands ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques associés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux à considérer ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines peut affecter la fonction des motifs EF Hands."
}
},
{
"@type": "Question",
"name": "Comment le stress influence-t-il les motifs EF Hands ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut perturber la signalisation calcique, affectant indirectement ces motifs."
}
},
{
"@type": "Question",
"name": "L'exercice physique a-t-il un impact sur ces motifs ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exercice régule la signalisation calcique, ce qui peut soutenir la fonction des motifs."
}
},
{
"@type": "Question",
"name": "Les suppléments de calcium sont-ils bénéfiques ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des suppléments peuvent aider à maintenir un bon équilibre calcique, soutenant la fonction."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les motifs EF Hands ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de traitements spécifiques pour les motifs EF Hands."
}
},
{
"@type": "Question",
"name": "Peut-on modifier les motifs EF Hands par thérapie génique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique pourrait potentiellement corriger des mutations affectant ces motifs."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils influencer les motifs EF Hands ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments modulent la signalisation calcique, indirectement affectant ces motifs."
}
},
{
"@type": "Question",
"name": "Y a-t-il des approches expérimentales pour traiter les anomalies ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours sur des peptides et des inhibiteurs ciblant les motifs EF Hands."
}
},
{
"@type": "Question",
"name": "Comment la nutrition peut-elle influencer les motifs EF Hands ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une nutrition adéquate en calcium et en magnésium peut soutenir leur fonction."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des motifs EF Hands défectueux ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications peuvent inclure des troubles neurologiques et musculaires."
}
},
{
"@type": "Question",
"name": "Les motifs EF Hands sont-ils liés à des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent un lien potentiel entre des anomalies et certains types de cancer."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des limitations fonctionnelles et des douleurs chroniques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de maladies cardiovasculaires ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dysfonctionnements calciques peuvent contribuer à des maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies des motifs EF Hands ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques et des expositions environnementales."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les motifs EF Hands ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut affecter la fonction des motifs EF Hands et la signalisation calcique."
}
},
{
"@type": "Question",
"name": "Le mode de vie joue-t-il un rôle dans les risques ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sédentaire et une mauvaise alimentation augmentent les risques."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles affecter les motifs EF Hands ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent perturber la signalisation calcique, affectant ces motifs."
}
}
]
}
]
}
RG Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany.
Leibniz Group 'Dendritic Organelles and Synaptic Function', University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Hamburg, Germany.
Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Russia. epermyak@yandex.ru.
Department of Biomedical Engineering, Pushchino State Institute of Natural Sciences, 142290 Pushchino, Russia. epermyak@yandex.ru.
Infections caused by antimicrobial-resistant bacteria are a significant cause of death worldwide, and carbapenemase-producing bacteria are the principal agents. New Delhi metallo-beta-lactamase-1 prod...
A retrospective case-control study with patients hospitalized from January 2012 to February 2018 at the Hospital Civil de Guadalajara "Fray Antonio Alcalde" was designed. During this period, 139 patie...
One hundred and thirty-nine case patients with a KP-NDM-1 isolate and 486 control patients were analyzed. In the case group, acute renal failure was a significant comorbidity, hospitalization days wer...
In this study, the previous use of antibiotics, the use of a urinary catheter, the use of a central venous catheter, the use of mechanical ventilation, and ICU stay were shown to be predictors of infe...
While errors can harm patients they remain poorly studied. This study characterized errors in the care of surgical patients and examined the association of errors with morbidity and mortality....
Errors have been reported to cause <10% or >60% of adverse events. Such discordant results underscore the need for further exploration of the relationship between error and adverse events....
Patients with operations performed at a single institution and abstracted into the American College of Surgeons National Surgical Quality Improvement Program from January 1, 2018, to December 31, 2018...
Of 1899 patients, 170 were defined as cases who experienced a morbidity or mortality. The majority of cases (n=93; 55%) had at least 1 error; of the 329 matched control patients, 112 had at least 1 er...
Errors in surgical care were associated with postoperative morbidity. Reducing errors requires measurement of errors....
Iron deficiency is a common problem in subfertile women. The influence of iron status on unexplained infertility is unknown....
In a case-control study, 36 women with unexplained infertility and 36 healthy non-infertile controls were included. Parameters of iron status including serum ferritin and a serum ferritin <30 µg/dL se...
Women with unexplained infertility demonstrated a lower transferrin saturation (median 17.3%, IQR 12.7-25.2 versus 23.9%, IQR 15.4-31.6;...
Ferritin levels <30µg/L were associated with unexplained infertility and might be screened in the future. Further studies with a focus on iron deficiency and iron treatment on women with unexplained i...
There are few studies published referring to bariatric surgery in patients older than 70 years. The aim of this study is to evaluate whether there are benefits to performing sleeve gastrectomy (SG) in...
Data were retrospectively collected from a Private Clinic's electronic medical records of patients undergoing SG between June 2017 and September 2020. Inclusion criteria were patients older than 70 ye...
Fifty patients were included in the study. Both groups were similar regarding gender, weight, BMI, and presence of DM. The 30-day morbidity and mortality were similar between the groups. The patients ...
The sleeve gastrectomy surgery performed in patients over 70 years of age is safe. The early results suggest similar benefits regarding weight loss and improvement of comorbidities to those having SG ...
The etiology of diverticulitis is multifactorial and poorly understood. We estimated the familiality of diverticulitis using the Utah Population Database, a statewide database linking medical records ...
We identified patients with diverticulitis diagnosed between 1998 and 2018 and age- and sex-matched controls in the Utah Population Database. Risk of diverticulitis in family members of patients and c...
The study population included 9,563 diverticulitis patients (with 229,647 relatives) and 10,588 controls (with 265,693 relatives). Relatives of patients were more likely to develop diverticulitis (inc...
Our results indicate that the first-, second-, and third-degree relatives of diverticulitis patients are at elevated risk of developing diverticulitis. This information may aid surgeons in counseling ...
This study aimed to investigate the clinical and laboratory as well as radiological features of spondyloarthritis (SpA) patients with thrombocytosis and to explore risk factor for thrombocytosis in Sp...
A total of 145 patients with SpA were included in this study, and non-thrombocytosis was identified in 76 patients while thrombocytosis was found in 69 patients, 38 out of the 69 patients received ant...
The proportion of hip involvement (60.86% vs 36.84%, p = 0.004), bath ankylosing spondylitis disease activity index score (4.24 ± 0.55 vs 3.69 ± 0.67, p < 0.001), erythrocyte sedimentation rate (62.22...
SpA patients with thrombocytosis have a higher proportion of hip involvement and disease activity compared to non-thrombocytosis SpA patients. The potential risk factors for thrombocytosis in SPA pati...
Recent studies of the vaginal microbiome have led to a better understanding of the microbiota and interactions with the host environment, however the role of the vaginal microbiome in vestibulodynia r...
This study aims to investigate and examine differences in the bacterial and fungal microbiome among patients with vestibulodynia and healthy controls....
A case-control study was conducted examining the vaginal microbiome of 29 patients with vestibulodynia and 26 controls through Stony Brook University Obstetrics and Gynecology ambulatory clinic. Exclu...
Principal component analysis (PCA) and linear discriminant analysis effect size (LefSe) were used to identify differences in relative abundance of operational taxonomic units (OTUs) for the vaginal mi...
Lactobacillus species were dominant amongst both cases and controls. PCA of 16S and ITS OTUs did not show significant differences in microbiome composition between vestibulodynia patients and controls...
Additional studies are needed to further assess the clinical significance of these findings....
Strengths of this study include ITS amplicon sequence analysis for fungal species diversity. Limitations of this study include small sample size and lack of racial diversity....
Our study did not find significant differences in composition or diversity between the vaginal microbiomes of cases of vestibulodynia and controls; however, the data suggests differences in abundance ...
Varied reports suggest a contentious relationship of bladder malignancy with pioglitazone in patients with type 2 diabetes....
To study an association (prevalence and predictors) of bladder malignancy with pioglitazone therapy in Asian-Indian type 2 diabetes patients....
In this observational multicenter study, type 2 diabetic patients attending out-patient diabetes-clinic were evaluated. A detailed history of anti-diabetic medication, dose, duration, pioglitazone usa...
A total of 8000 patients were screened out of which 1560 were excluded. Among 6440 included patients, 1056 (16.3%) patients were in group A and 5384 (83.6%) group B. Patients on pioglitazone were olde...
Pioglitazone use in Asian-Indians is not associated with an increased bladder cancer risk. However, pioglitazone should be restricted in individuals with history of hematuria. Age more than 58 years i...
Multiple chemical sensitivity (MCS) is a chronic condition characterized by the appearance of symptoms caused by exposure to chemical compounds that are tolerable for the general population. It mainly...
Stroke is the leading cause of mortality in China. DNA methylation has essential roles in multiple diseases, but its association with stroke was barely studied. We hereby explored the association betw...
The association was discovered in a hospital-based case-control study (cases/controls = 190:190) and further validated in a prospective nested case-control study including 139 cases who developed stro...
In our study, altered HTRA1 methylation was associated with stroke at clinical and preclinical stages and thus may provide a potential biomarker in the blood for the risk evaluation and preclinical de...