Quelles complications peuvent survenir avec des anomalies des MAR ?
Les complications incluent des troubles du développement et un risque accru de cancers.
ComplicationsTroubles du développement
#2
Les anomalies des MAR peuvent-elles entraîner des maladies chroniques ?
Oui, certaines anomalies peuvent contribuer à des maladies chroniques comme le cancer.
Maladies chroniquesCancers
#3
Y a-t-il des complications liées aux traitements des MAR ?
Les traitements peuvent avoir des effets secondaires, mais pas spécifiquement liés aux MAR.
Effets secondairesTraitements
#4
Les complications sont-elles réversibles ?
Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes.
RéversibilitéGestion des complications
#5
Les anomalies des MAR affectent-elles la fertilité ?
Certaines anomalies peuvent influencer la fertilité, mais cela dépend du contexte génétique.
FertilitéAnomalies génétiques
Facteurs de risque
5
#1
Quels sont les facteurs de risque pour les anomalies des MAR ?
Les facteurs incluent des prédispositions génétiques et des expositions environnementales.
Facteurs de risquePrédispositions génétiques
#2
L'âge influence-t-il les anomalies des MAR ?
Oui, l'âge avancé peut augmenter le risque de mutations génétiques, y compris dans les MAR.
ÂgeMutations génétiques
#3
Le mode de vie affecte-t-il les MAR ?
Oui, des habitudes comme le tabagisme et l'alimentation peuvent influencer les MAR.
Mode de vieTabagisme
#4
Les antécédents familiaux jouent-ils un rôle ?
Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque d'anomalies.
Antécédents familiauxMaladies génétiques
#5
Les agents environnementaux influencent-ils les MAR ?
Oui, l'exposition à des agents cancérigènes peut affecter l'intégrité des MAR.
Agents environnementauxCancers
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"@type": "Question",
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"@type": "Question",
"name": "Quels symptômes sont liés aux anomalies des MAR ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les anomalies des MAR peuvent entraîner des dysfonctionnements cellulaires, mais pas de symptômes spécifiques."
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"@type": "Question",
"name": "Les MAR affectent-elles l'expression génique ?",
"position": 7,
"acceptedAnswer": {
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"@type": "Question",
"name": "Y a-t-il des symptômes associés aux cancers liés aux MAR ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes dépendent du type de cancer, mais peuvent inclure fatigue, douleur, et perte de poids."
}
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{
"@type": "Question",
"name": "Les MAR influencent-elles le développement embryonnaire ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les MAR sont impliquées dans la régulation des gènes essentiels au développement embryonnaire."
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{
"@type": "Question",
"name": "Les anomalies des MAR peuvent-elles causer des troubles ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies peuvent contribuer à des troubles du développement ou des cancers."
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{
"@type": "Question",
"name": "Peut-on prévenir les anomalies des MAR ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques de maladies associées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests de dépistage pour les anomalies des MAR ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de tests de dépistage spécifiques pour les anomalies des MAR."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque de cancers liés aux MAR ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les facteurs de risque connus comme le tabagisme et l'exposition à des agents cancérigènes."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les MAR ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut influencer l'expression génique, y compris celle des MAR."
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"name": "Les examens médicaux réguliers aident-ils ?",
"position": 15,
"acceptedAnswer": {
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"text": "Oui, des examens réguliers peuvent aider à détecter précocement des maladies associées."
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{
"@type": "Question",
"name": "Y a-t-il des traitements ciblant les MAR ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de traitements spécifiques ciblant les MAR."
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{
"@type": "Question",
"name": "Comment les thérapies géniques affectent-elles les MAR ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
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{
"@type": "Question",
"name": "Les traitements du cancer affectent-ils les MAR ?",
"position": 18,
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"position": 19,
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"position": 20,
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"@type": "Answer",
"text": "Indirectement, en modifiant l'environnement cellulaire, mais pas directement les MAR."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies des MAR ?",
"position": 21,
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"@type": "Answer",
"text": "Les complications incluent des troubles du développement et un risque accru de cancers."
}
},
{
"@type": "Question",
"name": "Les anomalies des MAR peuvent-elles entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines anomalies peuvent contribuer à des maladies chroniques comme le cancer."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications liées aux traitements des MAR ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent avoir des effets secondaires, mais pas spécifiquement liés aux MAR."
}
},
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"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 24,
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"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Les anomalies des MAR affectent-elles la fertilité ?",
"position": 25,
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"@type": "Answer",
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},
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"position": 26,
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}
},
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"name": "L'âge influence-t-il les anomalies des MAR ?",
"position": 27,
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"@type": "Answer",
"text": "Oui, l'âge avancé peut augmenter le risque de mutations génétiques, y compris dans les MAR."
}
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{
"@type": "Question",
"name": "Le mode de vie affecte-t-il les MAR ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes comme le tabagisme et l'alimentation peuvent influencer les MAR."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque d'anomalies."
}
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"@type": "Question",
"name": "Les agents environnementaux influencent-ils les MAR ?",
"position": 30,
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"@type": "Answer",
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Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, Henan, China.
International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, Henan, China.
International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, Henan, China; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Owerko Centre for Children's Neurodevelopment and Mental Health, Alberta Children's Hospital Research Institute, Faculty of Nursing, University of Calgary, Calgary, AB T2N 1N4, Canada.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Owerko Centre for Children's Neurodevelopment and Mental Health, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB T2N 1N4, Canada.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Owerko Centre for Children's Neurodevelopment and Mental Health, Alberta Children's Hospital Research Institute, Departments of Pediatrics, Psychiatry, and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, Henan, China.
International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, Henan, China; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Publications dans "Régions d'ancrage à la matrice nucléaire" :
The persistent stigma associated with mental health conditions is a major challenge worldwide. Celebrities may improve this by openly discussing their own mental health issues, potentially influencing...
To evaluate the impact of celebrity mental health disclosures on the incidence and prevalence of panic disorder diagnosis in South Korea....
This cohort study included the entire South Korean population from January 2004 to December 2021, as reflected in the National Health Insurance Service data. Analysis was conducted from May 2022 throu...
Time periods analyzed included the timeframe before (from January 2004 to December 2010) and after the public disclosures of panic disorder by 3 high-profile Korean celebrities between December 2010 a...
Monthly incidence and prevalence of panic disorder, defined by the presence of a clinical diagnosis of the condition. Trends were assessed using interrupted time series analysis with autoregressive in...
The study covered the entire population of South Korea, including 48 559 946 individuals in January 2004 and 52 593 886 individuals in December 2021. Before 2011, the mean (SD) annual prevalence of pa...
In this observational cohort study, celebrity disclosure of mental health conditions was associated with a sustained reduction in stigma, as reflected in increased help-seeking behavior for the condit...
Optical coherence tomography (OCT) is a novel method that allows high resolution cross-sectional imaging of biological tissues. It was suggested that changes in the cranial structure or functions woul...
The study group included 21 PD patients who met the study criteria. The control group included 21 healthy individuals without any known psychiatric or organic disease, including eye disease, and gende...
In the study, it was determined that the CMT values of the PD patients were lower when compared to the controls in the OCT examination. There was a statistically significant difference between the CMT...
This is the first study in the literature where patients with a PD diagnosis were analyzed based on the OCT method. OCT, which is a simple, noninvasive and relatively inexpensive method that the patie...
Anxiety disorders affect blood pressure both during the day and at night. Little is known about the effect of individual anxiety disorders on the circadian rhythm of blood pressure....
The purpose of this study is to compare the nocturnal drop in blood pressure in patients with panic disorder (PD), generalized anxiety disorder (GAD), and healthy individuals....
The study was conducted on fifty consecutive outpatients with anxiety disorders and personality disorders who participated in intensive group psychotherapy. Diagnoses were made according to DSM-IV-TR ...
Mean nocturnal falls in systolic and diastolic blood pressure were the following: 2% and 3% (PD), 11% and 12% (GAD), 27% and 23% (control). Four people out of PD group had higher systolic and diastoli...
The patients with PD were characterized by an almost flat course of circadian blood pressure. The patients with GAD had a lower mean nocturnal fall in blood pressure than the control group, but signif...
Panic disorder is one of the most commonly occurring emotional disorder, showing increased prevalence rates since the COVID-19 pandemic. The ever-growing number of patients in need of treatment is a h...
Based on Salkovskis and Clark (1986), we developed a 5 session, intensive cognitive behavioral group therapy protocol for panic patients....
Effectiveness of the short group therapy was assessed with questionnaires (Spielberger's State-Trait Anxiety Inventory, Beck Depression Inventory) and an additional subjective scale. Paired sample t-t...
Our results suggest that the intensity of anxiety and depressive symptoms (t(36) = 5.497, p<0.0001; Z = -4.871, p<0.0001) as well as the frequency of panic attacks (Z= -5.190, p<0.0001) decreased sign...
Our clinical study provides further evidence by the effectiveness of low-intensity psychological interventions, offering an evidence-based protocol for professionals working in primary as well as ment...
Panic disorder is a debilitating anxiety disorder that has a serious impact on adolescents' social and academic functioning and general wellbeing. Panic disorder is experienced by around 1 to 3% of th...
Semi-structured interviews were conducted with eight adolescents with a primary diagnosis of panic disorder. Interpretative Phenomenological Analysis was used to gain an understanding of adolescents' ...
Two superordinate themes were identified: (1) Drowning in sensations, and (2) An unacceptable self. The findings show that adolescents experience panic disorder as extremely overwhelming and unpleasan...
These findings offer new insight into these adolescents' lived experience of panic disorder and highlight the need for adolescents to access timely, evidence-based treatment, as well as the need for i...
The potential association between oxytocin (OXT) plasma levels and clinical and hormonal parameters in panic disorder (PD) especially in its acute phase - has not been investigated as yet. This was th...
Twenty-four consecutively-referred, acutely-ill, medication-free PD patients with (PDA,...
OXT levels were significantly, negatively associated with the HARS scores (...
In acutely-ill, medication-free PD patients, OXT plasma levels may be relevant to the severity of their 'general' anxiety symptoms, but not to the 'specific' panic psychopathology....
A panic attack is a discrete period of fear or anxiety that has a rapid onset and reaches a peak within 10 minutes. The main symptoms involve bodily systems, such as racing heart, chest pain, sweating...
To compare, via network meta-analysis, individual drugs (antidepressants and benzodiazepines) or placebo in terms of efficacy and acceptability in the acute treatment of panic disorder, with or withou...
We searched the Cochrane Common Mental Disorders Specialised Register, CENTRAL, CDSR, MEDLINE, Ovid Embase and PsycINFO to 26 May 2022....
We included randomised controlled trials (RCTs) of people aged 18 years or older of either sex and any ethnicity with clinically diagnosed panic disorder, with or without agoraphobia. We included tria...
Two authors independently screened titles/abstracts and full texts, extracted data and assessed risk of bias. We analysed dichotomous data and continuous data as risk ratios (RRs), mean differences (M...
Overall, we included 70 trials in this review. Sample sizes ranged between 5 and 445 participants in each arm, and the total sample size per study ranged from 10 to 1168. Thirty-five studies included ...
In terms of efficacy, SSRIs, SNRIs (venlafaxine), TCAs, MAOIs and BDZs may be effective, with little difference between classes. However, it is important to note that the reliability of these findings...
This study aimed to detect altered brain activation pattern of patients with panic disorder (PD) and its changes after treatment. The possibilities of diagnosis and prediction of treatment response ba...
Fifty-four PD patients and 54 healthy controls (HCs) were recruited. Clinical assessment and resting-state functional magnetic resonance imaging scans were conducted. Then, patients received a 4-week ...
Lower fALFF values in the right calcarine/lingual gyrus and left lingual gyrus/cerebellum IV/V, whereas higher fALFF values in right cerebellum Crus II were observed in patients related to HCs at base...
The impacts of ethnic, cultural, and other regional differences on PD were not considered for it was a single-center study....
The occipital-cerebellum network played an important role in the pathophysiology of PD and should be a part of the fear network. The abnormal fALFF values in patients with PD at pretreatment could ser...
Cognitive behavioral therapy (CBT) and pharmacotherapy with antidepressants are both a highly effective treatment for agoraphobia and/or panic disorder; however, a combination of CBT and antidepressan...
Out of a total of n = 488 patients medication use during treatment was retrospectively determined for n = 380: n = 100 (26.3%) were taking antidepressants of different drug classes. Calculations were ...
Patients with existing antidepressant medication more often met the criteria for comorbid depressive disorder (p < 0.001). The measure of symptom change and treatment response rates did not differ bet...
In the context studied, patients with and without existing antidepressant medication benefited equally from CBT with respect to anxiety symptoms....
The aims of this study were to conduct a cross-cultural validation of the Panic Disorder Severity Scale - Self-Report (PDSS-SR) and to examine psychometric properties of the French-Canadian version....
A sample of 256 adults were included in the validation study based on data from the baseline interview of a clinical trial on transdiagnostic cognitive-behavioral therapy for mixed anxiety disorders. ...
The French version of the PDSS-SR demonstrated good psychometric properties. The exploratory factor analysis supported a one factor structure with an eigenvalue > 1 that explained 64.9% of the total v...
The French version of the PDSS-SR has psychometric properties consistent with the original version and constitutes a valid brief scale to assess the severity of panic disorder and change in severity o...