questionsmedicales.fr
Composés polycycliques
Composés macrocycliques
Lactames macrocycliques
Lactames macrocycliques : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Infections bactériennes
Cultures bactériennes
Antibiotiques
Tests de sensibilité
Efficacité
Cultures positives
Imagerie médicale
Infections profondes
Symptômes
5
Symptômes
Infections bactériennes
Effets secondaires
Eruptions cutanées
Réaction allergique
Démangeaisons
Prévention
5
Prophylaxie
Infections post-chirurgicales
Vaccinations
Infections bactériennes
Résistance aux antibiotiques
Prescriptions médicales
Traitements
5
Administration
Voie intraveineuse
Mécanisme d'action
Paroi cellulaire
Durée du traitement
Infections
Effets secondaires
Ajustement du traitement
Complications
5
Complications
Réactions allergiques
Surinfection
Évaluation médicale
Troubles rénaux
Surveillance
Réaction sévère
Urgence médicale
Interactions médicamenteuses
Médecin
Facteurs de risque
5
Facteurs de risque
Immunodépression
Antécédents médicaux
Allergies
Personnes âgées
Système immunitaire
Voyages
Agents pathogènes
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"name": "Comment diagnostiquer une infection bactérienne ?",
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{
"@type": "Question",
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"position": 2,
"acceptedAnswer": {
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},
{
"@type": "Question",
"name": "Quels symptômes indiquent une infection nécessitant des lactames ?",
"position": 3,
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"@type": "Question",
"name": "Quels sont les symptômes d'une infection bactérienne ?",
"position": 6,
"acceptedAnswer": {
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"@type": "Question",
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{
"@type": "Question",
"name": "Comment reconnaître une réaction allergique ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des démangeaisons, un gonflement ou des difficultés respiratoires peuvent indiquer une allergie."
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{
"@type": "Question",
"name": "Quels signes d'infection nécessitent une attention médicale ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une fièvre élevée persistante ou des douleurs intenses doivent être évaluées par un médecin."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques affectent-ils le système digestif ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent causer des nausées, vomissements ou diarrhées chez certains patients."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections bactériennes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hygiène, des vaccinations et un usage prudent des antibiotiques aident à prévenir."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques sont-ils utilisés en prophylaxie ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent être utilisés en prophylaxie pour prévenir des infections post-chirurgicales."
}
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{
"@type": "Question",
"name": "Quelles mesures d'hygiène sont recommandées ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Se laver les mains régulièrement et éviter le contact avec des personnes malades sont essentiels."
}
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{
"@type": "Question",
"name": "Les vaccinations aident-elles contre les infections ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines vaccinations peuvent réduire le risque d'infections bactériennes spécifiques."
}
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{
"@type": "Question",
"name": "Comment éviter la résistance aux antibiotiques ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser les antibiotiques uniquement lorsque nécessaire et suivre les prescriptions médicales."
}
},
{
"@type": "Question",
"name": "Comment les lactames macrocycliques sont-ils administrés ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent être administrés par voie intraveineuse ou orale, selon l'infection."
}
},
{
"@type": "Question",
"name": "Quel est le mécanisme d'action des lactames ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils inhibent la synthèse de la paroi cellulaire bactérienne, entraînant la mort des bactéries."
}
},
{
"@type": "Question",
"name": "Combien de temps dure un traitement typique ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La durée du traitement varie, mais elle est généralement de 7 à 14 jours selon l'infection."
}
},
{
"@type": "Question",
"name": "Quels antibiotiques sont des lactames macrocycliques ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exemples incluent la méropénème et l'imipénème, utilisés pour des infections graves."
}
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"@type": "Question",
"name": "Comment gérer les effets secondaires des lactames ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est important de signaler tout effet indésirable au médecin pour ajuster le traitement."
}
},
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"@type": "Question",
"name": "Quelles complications peuvent survenir avec les lactames ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des réactions allergiques graves ou des infections secondaires peuvent survenir."
}
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{
"@type": "Question",
"name": "Comment gérer une surinfection ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une évaluation médicale est nécessaire pour ajuster le traitement et cibler la nouvelle infection."
}
},
{
"@type": "Question",
"name": "Les lactames peuvent-ils causer des troubles rénaux ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains lactames peuvent affecter la fonction rénale, nécessitant une surveillance."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'une réaction sévère ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des difficultés respiratoires ou un gonflement du visage nécessitent une urgence."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques peuvent-ils interagir avec d'autres médicaments ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent interagir avec d'autres médicaments, il est donc important d'informer le médecin."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'infection ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunodépression, le diabète et les interventions chirurgicales augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les antécédents d'allergies influencent-ils le traitement ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents d'allergies aux antibiotiques peuvent limiter les options de traitement."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'infection ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent augmenter le risque."
}
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{
"@type": "Question",
"name": "Les personnes âgées sont-elles plus à risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées ont un système immunitaire affaibli, les rendant plus vulnérables."
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"@type": "Question",
"name": "Les voyages augmentent-ils le risque d'infections ?",
"position": 30,
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"text": "Oui, les voyages peuvent exposer à des agents pathogènes inconnus, augmentant le risque d'infection."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 15/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, United States.
Publications dans "Lactames macrocycliques" :
3 publications dans cette catégorie
Affiliations :
College of Sciences, Center for Supramolecular Chemistry and Catalysis, Shanghai University, Shanghai, 200444, People's Republic of China. cjli@shu.edu.cn.
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin, 300387, People's Republic of China. cjli@shu.edu.cn.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin, 300387, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Centro de Investigacións Cientı́ficas Avanzadas (CICA) and Departamento de Quı́mica, Universidade da Coruña, Campus da Zapateira-Rúa da Fraga 10, 15008 A Coruña, Spain.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Centro de Investigacións Cientı́ficas Avanzadas (CICA) and Departamento de Quı́mica, Universidade da Coruña, Campus da Zapateira-Rúa da Fraga 10, 15008 A Coruña, Spain.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Natural Products Research Institute, College of Pharmacy , Seoul National University , Seoul 08826 , Republic of Korea.
Publications dans "Lactames macrocycliques" :
Herein we report a cluster of five patients with confirmed...
This case cluster suggests that the toxin of...
Saponins are a large group of organic amphiphilic substances (surfactants) mainly extracted from herbs with biological activity, considered as one of the main ingredients in numerous remedies used in ...
Sporadic mechanically-induced hemolysis associated with kinks in extracorporeal blood circuits during hemodialysis is a rare but potentially serious complication that exhibits laboratory features cons...
Warm antibody-mediated autoimmune hemolysis (WAIHA) is most often due to immunoglobulin G (IgG) antibodies and is detected by direct antiglobulin test (DAT). However, about 10% cases of hemolytic anem...
We isolated patient and control IgA on Jacalin agarose. Isolated IgA was used to sensitize healthy ABO/Rh-matched donor red blood cells (RBC). Antibody binding was examined by flowcytometry. The effec...
We show that isolated IgA from the serum can bind to red cells. In addition, RBCs were phagocytosed efficiently by autologous macrophages in the presence of patient IgA....
Our results show that IgA antibodies are capable of inducing erythrophagocytosis like IgG antibodies in the absence of complement fixation....
In vitro determination of hemolytic properties is a common and important method for preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical device or material. The ...
Minimizing hemolysis during phlebotomy ensures accurate chemistry results and reduces test cancellations and specimen recollections. We developed videos demonstrating best practices to reduce hemolysi...
Videos of common blood collections demonstrating best practices to reduce hemolysis were filmed and then distributed via email link to all hospital-based CNEs in Calgary, Alberta, Canada. (https://vim...
In +/- 3 months of data flanking video distribution (n = 137 241 collections), where overall impact was strongest, H-index trajectory (change in units per week) decreased immediately following video d...
We developed a novel and convenient educational aid that, when distributed, was associated with beneficial changes in specimen hemolysis at hospital inpatient units and outpatient clinics. Including i...
Carbon monoxide (CO)-based tests have precisely measured hemolysis for over 40 years. End-tidal CO was the primary marker in clinical hematology research, followed by carboxyhemoglobin. Quantification...
A patient presented with fever, severe pain and edematous tight due to hip trauma and was scheduled for urgent fasciotomy. Following physical examination, laboratory analyses were requested, and resul...
Hereditary spherocytosis (HS) is a common inherited hemolytic anemia, caused by mutations in five genes that encode erythrocyte membrane skeleton proteins. The red blood cell (RBC) lifespan could dire...
In the present cohort, we identified 8 ANK1,9 SPTB,5 SLC4A1 and 1 SPTA1 mutations in 23 patients with HS, and the median RBC lifespan was 14(8-48) days. The median RBC lifespan of patients with ANK1, ...
The present study is the first to investigate the potential association between genotype and degree of hemolysis in HS. The present findings indicated that there is no significant correlation between ...
Hemolysis is a common pre-analytical factor that can influence test results. Here, we explored the influence of hemolysis on nucleated red blood cells (NRBCs) count and tried to illustrate the mechani...
From July 2019 to June 2021, 20 preanalytical hemolytic peripheral blood (PB) samples from inpatient at Tianjin Huanhu Hospital were evaluated using Sysmex XE-5000 automated hematology analyzer. When ...
Hemolysis led to false-positive NRBC count and the value of NRBC was positively correlated with the degree of hemolysis. Hemolysis specimen shared a common scatter diagram: a "beard" on WBC/ basophil ...
In the present study, we firstly found that hemolysis could lead to false-positive NRBCs enumeration, which was associated with lipid droplets released from broken RBCs during hemolysis....