Comment diagnostiquer une dysfonction de MAPK3 ?

Des tests génétiques et des analyses de signalisation cellulaire peuvent être utilisés.

Quels tests sont utilisés pour évaluer MAPK3 ?

Les tests de phosphorylation et les analyses protéomiques sont courants.

Y a-t-il des biomarqueurs associés à MAPK3 ?

Des niveaux anormaux de certaines protéines peuvent indiquer une dysfonction de MAPK3.

MAPK3 est-elle impliquée dans des maladies spécifiques ?

Oui, elle est liée à des cancers et des maladies inflammatoires.

Quels symptômes peuvent indiquer un problème avec MAPK3 ?

Des symptômes variés selon la maladie, comme la fatigue ou des douleurs chroniques.

Quels symptômes sont liés à une activation excessive de MAPK3 ?

Une activation excessive peut entraîner une inflammation et des douleurs.

MAPK3 affecte-t-elle le système immunitaire ?

Oui, elle joue un rôle dans la régulation de la réponse immunitaire.

Quels signes cliniques sont associés à MAPK3 ?

Des signes comme des éruptions cutanées ou des troubles métaboliques peuvent apparaître.

Y a-t-il des symptômes neurologiques liés à MAPK3 ?

Des troubles neurologiques peuvent survenir en cas de dysfonction de MAPK3.

Comment la MAPK3 influence-t-elle le stress cellulaire ?

Elle régule les réponses au stress, affectant la survie cellulaire et l'apoptose.

Comment prévenir les dysfonctionnements de MAPK3 ?

Un mode de vie sain, incluant une bonne nutrition et de l'exercice, est recommandé.

Y a-t-il des habitudes à éviter pour MAPK3 ?

Éviter le tabagisme et une alimentation riche en graisses saturées est conseillé.

Le stress peut-il affecter MAPK3 ?

Oui, le stress chronique peut perturber la signalisation de MAPK3.

Des exercices spécifiques aident-ils MAPK3 ?

Des exercices réguliers peuvent améliorer la régulation de MAPK3.

La gestion du poids influence-t-elle MAPK3 ?

Maintenir un poids santé peut aider à réguler l'activité de MAPK3.

Quels traitements ciblent MAPK3 ?

Des inhibiteurs spécifiques de MAPK3 sont en développement pour traiter certains cancers.

La thérapie génique peut-elle corriger MAPK3 ?

La thérapie génique est une approche potentielle pour corriger des mutations de MAPK3.

Quels médicaments affectent la voie MAPK3 ?

Des médicaments comme les inhibiteurs de MEK peuvent moduler l'activité de MAPK3.

Y a-t-il des traitements naturels pour MAPK3 ?

Certaines plantes médicinales peuvent influencer la signalisation de MAPK3.

Comment la nutrition influence-t-elle MAPK3 ?

Une alimentation riche en antioxydants peut moduler l'activité de MAPK3.

Quelles complications peuvent survenir avec une dysfonction de MAPK3 ?

Des complications comme le cancer, l'inflammation chronique et des troubles métaboliques peuvent survenir.

MAPK3 est-elle liée à des maladies auto-immunes ?

Oui, des anomalies dans MAPK3 peuvent contribuer à des maladies auto-immunes.

Comment MAPK3 affecte-t-elle le cancer ?

Une activation aberrante de MAPK3 est souvent observée dans divers types de cancer.

Y a-t-il des risques cardiovasculaires liés à MAPK3 ?

Des études suggèrent un lien entre MAPK3 et des maladies cardiovasculaires.

MAPK3 peut-elle influencer le vieillissement ?

Des dysfonctionnements de MAPK3 sont associés à des processus de vieillissement prématuré.

Quels facteurs de risque sont associés à MAPK3 ?

Des facteurs comme l'obésité, le tabagisme et le stress sont des risques connus.

L'âge influence-t-il l'activité de MAPK3 ?

Oui, l'activité de MAPK3 peut diminuer avec l'âge, affectant la signalisation cellulaire.

Y a-t-il des prédispositions génétiques pour MAPK3 ?

Certaines mutations génétiques peuvent prédisposer à des dysfonctionnements de MAPK3.

Le mode de vie influence-t-il MAPK3 ?

Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent les risques.

Des infections peuvent-elles affecter MAPK3 ?

Certaines infections virales peuvent perturber la signalisation de MAPK3.

Mitogen-Activated Protein Kinase 3 - Informations médicales vérifiées

Safety of Endoscopic Sleeve Gastroplasty with a Single-Channel Endoscope.

09 2022

DOI: 10.1007/s11695-022-06210-w PMID: 35857182

Less invasive endoscopic bariatric procedures are under development for the management of class I of obesity. The purpose of our study is to evaluate the safety of endoscopic sleeve gastroplasty (ESG)... This is a retrospective single-center study over 191 patients using the ESG under general anesthesia with overnight inpatient observation between January 2019 and December 2020. The analyzed variables... A total of 191 patients underwent ESG for primary obesity. There were 173 female (90.6%) with a mean age of 36.9 years. The mean BMI was 33.7 kg/m... Endoscopic gastroplasty represents a safe minimal invasive approach with the new device OverStitch Sx™ that can be considered an effective and well-tolerated procedure especially for primary obesity t...

Adult Endoscopes Female Gastroplasty Humans +5 autres

The Advantages of Applying a 5-mm Endoscope in the Transoral Endoscopic Thyroidectomy Vestibular Approach.

01 Jun 2022

DOI: 10.1097/SLE.0000000000001051 PMID: 35482517

We sought to compare the effect of applying a 5-mm endoscope and a 10-mm endoscope in the transoral endoscopic thyroidectomy vestibular approach (TOETVA) and to clarify the advantages of using a 5-mm ... A retrospective analysis of the clinical data of 135 patients who were diagnosed with papillary thyroid carcinoma and who had undergone TOETVA in the thyroid disease center of The First Affiliated Hos... Compared with the 10-mm endoscope group, the 5-mm endoscope group had less surgical trauma, less injury to the mandibular muscles (orbicularis oris, depressor labii inferioris, and mentalis muscle), s... The application of a 5-mm endoscope not only improves the cosmetic effect of TOETVA but also reduces the degree of surgical trauma, saves the surgical space, improves the surgical efficiency, and redu...

Endoscopes Humans Natural Orifice Endoscopic Surgery Postoperative Complications Retrospective Studies +2 autres

Novel Colorectal Endoscopic Submucosal Dissection With Double-Endoscope and Snare-Based Traction.

01 07 2022

DOI: 10.1097/DCR.0000000000002355 PMID: 35675535

Colorectal endoscopic submucosal dissection is technically demanding, and the traction offered by gravity, cap, or clip-with-line during conventional endoscopic submucosal dissection remains unsatisfa... This study aimed to test the novel double-scope endoscopic submucosal dissection with snare-based traction.... This was a retrospective study that reviewed double-scope endoscopic submucosal dissection compared with matched conventional endoscopic submucosal dissection, and size, location, morphology, and path... This study was conducted in a referral endoscopy center in a local hospital.... This study included patients with colorectal lesions receiving double-scope endoscopic submucosal dissection and matched conventional endoscopic submucosal dissection.... The pathological completeness, procedure time, and complications were analyzed.... Fifteen double-scope endoscopic submucosal dissection procedures, with 11 lesions located in the proximal colon with a median size of 40 mm, were performed. The median procedure time of double-scope e... This was a single-center, single-operator, retrospective case-controlled study with limited cases.... This study confirmed the feasibility of double-scope endoscopic submucosal dissection with snare-based traction to shorten procedure time and to simplify endoscopic submucosal dissection. Additional t...

Colorectal Neoplasms Endoscopes Endoscopic Mucosal Resection Humans Retrospective Studies +2 autres

How effective are the alcohol flush and drying cycles of automated endoscope reprocessors? Stripped endoscope model.

05 2023

DOI: 10.1016/j.ajic.2023.02.008 PMID: 36842713

Effective drying of the internal channels of endoscopes is essential to prevent the growth of water-borne pathogens and to assure adequate sterilization with vaporized hydrogen peroxide or ethylene ox... Stripped endoscopes (SE) that allow for visual inspection of the inside channels were reprocessed per protocol in a large urban medical center, with a 3-minute or 10-minute air flush following reproce... All SE were grossly wet after HLD with a 3-minute air flush, despite alcohol flush and drying cycle. The 10-minute air flush was effective at drying the biopsy/suction channel, but not the air/water c... Air flush cycles commonly used in the final steps of automated endoscope reprocessing may not adequately dry endoscope channels, particularly the narrower diameter air/water channels. An extended 10-m...

Humans Desiccation Disinfection Endoscopes Endoscopes, Gastrointestinal +2 autres

Neuroendoscopy: history, endoscopes, and instrumentation.

10 2023

DOI: 10.1007/s00381-023-06090-0 PMID: 37542700

Endoscopy was first employed in the surgical treatment of neurosurgical diseases early in the twentieth century, but did not become an established practice for a long time, mainly because of poor tech... The expansion of ventricular endoscopy has led to significant understanding of CSF disorders. Aqueduct stenosis as cause of hydrocephalus and arachnoid cysts are an example of pathologies, the concept... We should always remember that the endoscope is only a tool. Its use has indications and limitations related to its design and our ability to extract the maximum, in the context of its shortcomings. F...

Humans Neuroendoscopy Neuroendoscopes Endoscopes Neurosurgical Procedures +1 autres

Purely endoscopic and endoscope-assisted approaches to lesions of the third ventricle in pediatric age-a technical collection.

Dec 2023

DOI: 10.1007/s00381-023-06030-y PMID: 37328661

One of the main difficulties in third ventricle surgery is its deep and central location within the brain, surrounded by many eloquent neurovascular structures. Such anatomical environment obviously m... The introduction of the surgical microscope into the neurosurgical field undoubtedly played an important and pivotal role in improving the surgical results and increasing the safety of operations in a... In this collection on purely endoscopic and endoscope-assisted approaches to lesions of the third ventricle in pediatric age, the readership is presented with a selected group of these operations perf...

Child Humans Brain Endoscopes Microsurgery +2 autres

Minimizing the Risks of Simethicone in Endoscope Reprocessing.

01 02 2023

DOI: 10.1097/MCG.0000000000001807 PMID: 36508253

This statement was written under the auspices of the World Gastroenterology Organization's Guidelines Committee. The authors are members of the Review Team of the WGO Endoscope Disinfection Guideline ...

Humans Simethicone Endoscopes Endoscopy, Gastrointestinal Disinfection +1 autres

Navigation Techniques in Endoscopic Spine Surgery.

2022

DOI: 10.1155/2022/8419739 PMID: 36072476

Endoscopic spine surgery (ESS) advances the principles of minimally invasive surgery, including minor collateral tissue damage, reduced blood loss, and faster recovery times. ESS allows for direct acc...

Endoscopes Endoscopy Minimally Invasive Surgical Procedures Spine

The Wales Endoscope: The First American Cystoscope.

12 2022

DOI: 10.1016/j.urology.2022.07.041 PMID: 35964785

Philipp Bozzini, a German army surgeon, in 1807 invented the Lichtleiter, the predecessor of the modern cystoscope. By the mid-1800s, several new instruments were created including one, a variation on... We researched the life of Philip Wales and the description of his cystoscope as well as Horatio Kern, the instrument maker that produced Wales' instrument. We examined the Wales cystoscope acquired by... Philip Skinner Wales (1837-1906) was a surgeon who entered the United States Navy in 1856 and served throughout the Civil War. He organized and held charge of the Naval Hospital at New Orleans during ... The Wales endoscope is unique in that it had an American inventor, was simple in design and cheap to produce. It is an important historical artifact and is one of the earliest and rarest cystoscopes d...

United States Humans Cystoscopes Wales Endoscopes +2 autres

A Real-Time Endoscope Motion Tracker.

2022

DOI: 10.1109/JTEHM.2022.3214148 PMID: 36457895

In colonoscopy, it is desirable to accurately localize the position of the endoscope's distal tip. Current tip localization techniques are not sufficient for recording the position and movement of the... A dual modality tracking method is developed to measure the motion of the endoscope's insertion tube in real time, including insertion length, rotation angle, and their velocities. Optical trackballs ... The accuracy of insertion length and rotational angle were measured. For speeds ≤ 10 mm/s, the median and 90th percentile insertion position errors were 0.88 mm and 2.2 mm, respectively. The insertion... The prototype device can precisely measure an unmodified endoscope's position, rotation, and motion in real time without significant accumulative error. The prototype device is small and compatible wi...

Humans Endoscopes Rotation Colonoscopy Movement +1 autres

Mitogen-Activated Protein Kinase 3 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Auteurs principaux

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