How To Read a Network Meta-analysis.
Network meta-analysis (NMA) expands upon traditional meta-analysis by integrating three or more interventions. This allows comparing interventions using evidence from trials that have compared pairs o...
Mitogen-Activated Protein Kinase 3 : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer une dysfonction de MAPK3 ?
Des tests génétiques et des analyses de signalisation cellulaire peuvent être utilisés.
#2
Quels tests sont utilisés pour évaluer MAPK3 ?
Les tests de phosphorylation et les analyses protéomiques sont courants.
#3
Y a-t-il des biomarqueurs associés à MAPK3 ?
Des niveaux anormaux de certaines protéines peuvent indiquer une dysfonction de MAPK3.
#4
MAPK3 est-elle impliquée dans des maladies spécifiques ?
Oui, elle est liée à des cancers et des maladies inflammatoires.
#5
Quels symptômes peuvent indiquer un problème avec MAPK3 ?
Des symptômes variés selon la maladie, comme la fatigue ou des douleurs chroniques.
Symptômes 5
#1
Quels symptômes sont liés à une activation excessive de MAPK3 ?
Une activation excessive peut entraîner une inflammation et des douleurs.
#2
MAPK3 affecte-t-elle le système immunitaire ?
Oui, elle joue un rôle dans la régulation de la réponse immunitaire.
#3
Quels signes cliniques sont associés à MAPK3 ?
Des signes comme des éruptions cutanées ou des troubles métaboliques peuvent apparaître.
#4
Y a-t-il des symptômes neurologiques liés à MAPK3 ?
Des troubles neurologiques peuvent survenir en cas de dysfonction de MAPK3.
#5
Comment la MAPK3 influence-t-elle le stress cellulaire ?
Elle régule les réponses au stress, affectant la survie cellulaire et l'apoptose.
Prévention 5
#1
Comment prévenir les dysfonctionnements de MAPK3 ?
Un mode de vie sain, incluant une bonne nutrition et de l'exercice, est recommandé.
#2
Y a-t-il des habitudes à éviter pour MAPK3 ?
Éviter le tabagisme et une alimentation riche en graisses saturées est conseillé.
#3
Le stress peut-il affecter MAPK3 ?
Oui, le stress chronique peut perturber la signalisation de MAPK3.
#4
Des exercices spécifiques aident-ils MAPK3 ?
Des exercices réguliers peuvent améliorer la régulation de MAPK3.
#5
La gestion du poids influence-t-elle MAPK3 ?
Maintenir un poids santé peut aider à réguler l'activité de MAPK3.
Traitements 5
#1
Quels traitements ciblent MAPK3 ?
Des inhibiteurs spécifiques de MAPK3 sont en développement pour traiter certains cancers.
#2
La thérapie génique peut-elle corriger MAPK3 ?
La thérapie génique est une approche potentielle pour corriger des mutations de MAPK3.
#3
Quels médicaments affectent la voie MAPK3 ?
Des médicaments comme les inhibiteurs de MEK peuvent moduler l'activité de MAPK3.
#4
Y a-t-il des traitements naturels pour MAPK3 ?
Certaines plantes médicinales peuvent influencer la signalisation de MAPK3.
#5
Comment la nutrition influence-t-elle MAPK3 ?
Une alimentation riche en antioxydants peut moduler l'activité de MAPK3.
Complications 5
#1
Quelles complications peuvent survenir avec une dysfonction de MAPK3 ?
Des complications comme le cancer, l'inflammation chronique et des troubles métaboliques peuvent survenir.
#2
MAPK3 est-elle liée à des maladies auto-immunes ?
Oui, des anomalies dans MAPK3 peuvent contribuer à des maladies auto-immunes.
#3
Comment MAPK3 affecte-t-elle le cancer ?
Une activation aberrante de MAPK3 est souvent observée dans divers types de cancer.
#4
Y a-t-il des risques cardiovasculaires liés à MAPK3 ?
Des études suggèrent un lien entre MAPK3 et des maladies cardiovasculaires.
#5
MAPK3 peut-elle influencer le vieillissement ?
Des dysfonctionnements de MAPK3 sont associés à des processus de vieillissement prématuré.
Facteurs de risque 5
#1
Quels facteurs de risque sont associés à MAPK3 ?
Des facteurs comme l'obésité, le tabagisme et le stress sont des risques connus.
#2
L'âge influence-t-il l'activité de MAPK3 ?
Oui, l'activité de MAPK3 peut diminuer avec l'âge, affectant la signalisation cellulaire.
#3
Y a-t-il des prédispositions génétiques pour MAPK3 ?
Certaines mutations génétiques peuvent prédisposer à des dysfonctionnements de MAPK3.
#4
Le mode de vie influence-t-il MAPK3 ?
Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent les risques.
#5
Des infections peuvent-elles affecter MAPK3 ?
Certaines infections virales peuvent perturber la signalisation de MAPK3.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/02/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Juan Wang
2 publications dans cette catégorie
Affiliations :
- Division of Integrative Bioscience and Biotechnology, College of Life Sciences, Sejong University, Seoul 05006, Republic of Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Mitogen-Activated Protein Kinase Kinase OsMEK2 Positively Regulates Ca
Antioxidants (Basel, Switzerland) 2024-08-20
-
Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways.
Stem cell research & therapy 2022-07-15
Mohammad Shafiq
2 publications dans cette catégorie
Affiliations :
- From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
- Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Kumaravelu Jagavelu
2 publications dans cette catégorie
Affiliations :
- From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
- Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Neeraj Kumar Verma
2 publications dans cette catégorie
Affiliations :
- Division of Molecular and Structural Biology (N.K.V., J.K.G.), CSIR-Central Drug Research Institute, Lucknow, India.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Jimut Kanti Ghosh
2 publications dans cette catégorie
Affiliations :
- Division of Molecular and Structural Biology (N.K.V., J.K.G.), CSIR-Central Drug Research Institute, Lucknow, India.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Matthias Gaestel
2 publications dans cette catégorie
Affiliations :
- Institute for Zellbiochemie, Medizinische Hochschule Hannover (MHH), Hanover, Germany (M.G.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Kashif Hanif
2 publications dans cette catégorie
Affiliations :
- From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
- Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension.
Hypertension (Dallas, Tex. : 1979) 2021-03-01
-
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension.
Life sciences 2021-10-20
Yu Liu
2 publications dans cette catégorie
Affiliations :
- Department of Radiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei, China.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer's disease.
Bioengineered
-
HOG1 Mitogen-Activated Protein Kinase Pathway-Related Autophagy Induced by H
Journal of fungi (Basel, Switzerland) 2023-03-28
Minchae Kim
1 publication dans cette catégorie
Affiliations :
- Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Mitogen-Activated Protein Kinase
Frontiers in plant science 2021-04-29
Soongon Jeong
1 publication dans cette catégorie
Affiliations :
- Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Mitogen-Activated Protein Kinase
Frontiers in plant science 2021-04-29
Chae Woo Lim
1 publication dans cette catégorie
Affiliations :
- Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Mitogen-Activated Protein Kinase
Frontiers in plant science 2021-04-29
Sung Chul Lee
1 publication dans cette catégorie
Affiliations :
- Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Mitogen-Activated Protein Kinase
Frontiers in plant science 2021-04-29
Tayeb Muhammad
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. tayebmuhammad@nwsuaf.edu.cn.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. tayebmuhammad@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Jie Zhang
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. 15591858981@163.com.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. 15591858981@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Yalin Ma
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. 15891785931@163.com.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. 15891785931@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Yushun Li
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. liyushunaf@163.com.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. liyushunaf@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Fei Zhang
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. feizhang@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Yan Zhang
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. zhangyan2014@nwsuaf.edu.cn.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. zhangyan2014@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Yan Liang
1 publication dans cette catégorie
Affiliations :
- College of Horticulture, Northwest A&F University, Yangling 712100, China. liangyan@nwsuaf.edu.cn.
- State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. liangyan@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Overexpression of a Mitogen-Activated Protein Kinase
Molecules (Basel, Switzerland) 2019-02-03
Kouichi Miura
1 publication dans cette catégorie
Affiliations :
- Division of Gastroenterology, Department of Medicine Jichi Medical University School of Medicine Shimotsuke Tochigi Japan.
Publications dans "Mitogen-Activated Protein Kinase 3" :
-
Is Mitogen-Activated Protein Kinase Phosphatase 5 a Solution to the Puzzle of the Mitogen-Activated Protein Kinase Signal in Steatohepatitis?
Hepatology communications 2019-06-03
Sources (10000 au total)
Methodological quality of network meta-analysis in dentistry: a meta-research.
This meta-research aimed to provide an overview of the methodological quality and risk of bias of network meta-analyses (NMA) in dentistry. Searches for NMA of randomized clinical trials with clinical...
Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis.
Non-pharmacological interventions have a myriad of available intervention options and contain multiple components. Whether specific components of non-pharmacological interventions or combinations are ... PubMed, Embase, Cochrane, CINAHL, PsycINFO, CENTRAL, Web of Science, and China's two largest databases, CNKI and Wanfang, were searched from inception to 22nd, January 2023. Randomized controlled tria... A total of 39 trials with 2959 patients were included (range of mean ages, 58.79-77.41 years). Resistance exercise might be the optimal intervention for reducing memory complaints in adults with subje... The form of physical activity performed appears to be more beneficial than cognitive interventions in reducing subjective memory complaints for adults with subjective cognitive decline, and this diffe... PROSPERO registry number. CRD42022355363....
Network meta-interpolation: Effect modification adjustment in network meta-analysis using subgroup analyses.
Effect modification (EM) may cause bias in network meta-analysis (NMA). Existing population adjustment NMA methods use individual patient data to adjust for EM but disregard available subgroup informa...
Treatments for alopecia areata: a network meta-analysis.
Alopecia areata is an autoimmune disease leading to nonscarring hair loss on the scalp or body. There are different treatments including immunosuppressants, hair growth stimulants, and contact immunot... To assess the benefits and harms of the treatments for alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) in children and adults.... The Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, ClinicalTrials.gov and WHO ICTRP were searched up to July 2022.... We included randomised controlled trials (RCTs) that evaluated classical immunosuppressants, biologics, small molecule inhibitors, contact immunotherapy, hair growth stimulants, and other therapies in... We used the standard procedures expected by Cochrane including assessment of risks of bias using RoB2 and the certainty of the evidence using GRADE. The primary outcomes were short-term hair regrowth ... We included 63 studies that tested 47 different treatments in 4817 randomised participants. All trials used a parallel-group design except one that used a cross-over design. The mean sample size was 7... We found that treatment with baricitinib results in an increase in short- and long-term hair regrowth compared to placebo. Although we found inconclusive results for the risk of serious adverse effect...
Bias propagation in network meta-analysis models.
Network meta-analysis combines direct and indirect evidence to compare multiple treatments. As direct evidence for one treatment contrast may be indirect evidence for other treatment contrasts, biases...
Does type of funding affect reporting in network meta-analysis? A scoping review of network meta-analyses.
Evidence has shown that private industry-sponsored randomized controlled trials (RCTs) and meta-analyses are more likely to report intervention-favourable results compared with other sources of fundin... To (a) explore the recommendation rate of industry-sponsored NMAs on their company's intervention, and (b) assess reporting in NMAs of pharmacologic interventions according to their funding type.... Design: Scoping review of published NMAs with RCTs.... We used a pre-existing NMA database including 1,144 articles from MEDLINE, EMBASE and Cochrane Database of Systematic Reviews, published between January 2013 and July 2018.... NMAs with transparent funding information and comparing pharmacologic interventions with/without placebo.... We captured whether NMAs recommended their own or another company's intervention, classified NMAs according to their primary outcome findings (i.e., statistical significance and direction of effect), ... We retrieved 658 NMAs, which reported a median of 23 items in the PRISMA-NMA checklist (interquartile range [IQR]: 21-26). NMAs were categorized as 314 publicly-sponsored (PRISMA-NMA median 24.5, IQR ... Differences in completeness of reporting and author characteristics were apparent among NMAs with different types of funding. Publicly-sponsored NMAs had the best reporting and published their finding...
Efficacy of innovative therapies in myasthenia gravis: A systematic review, meta-analysis and network meta-analysis.
Therapy for myasthenia gravis (MG) is undergoing a profound change, with new treatments being tested. These include complement inhibitors and neonatal Fc receptor (FcRn) blockers. The aim of this stud... We assessed statistical heterogeneity across trials based on the Cochrane Q test and I... We observed an overall mean Myasthenia Gravis-Activities of Daily Living scale (MG-ADL) score change of -2.17 points (95% confidence interval [CI] -2.67, -1.67; p < 0.001) as compared to placebo. No s... Anti-complement and FcRn treatments both proved to be effective in MG patients, whereas rituximab did not show a significant benefit for patients. Within the limitations of this meta-analysis, includi...
Effectiveness of aerobic exercise in the prevention and treatment of postpartum depression: Meta-analysis and network meta-analysis.
Aerobic exercise is widely recognized for improving mental health and reducing negative emotions, including anxiety. However, research on its role in preventing and treating postpartum depression (PPD... We conducted a quantitative systematic review of the study in 5 representative databases for the effect of aerobic exercise on PPD. Meta-analysis and network meta-analysis were performed with Review-M... Twenty-six studies with 2,867 participants were eventually included and the efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care. (MD ... The efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care, with a greater emphasis on prevention. The optimal prescribed exercise volum...
Antibiotic Prophylaxis in Reduction Mammaplasty: A Network Meta-Analysis.
Mounting evidence suggests that breast reduction surgery displays higher rates of surgical site infections (SSI) than initially presumed. Objective of this network meta-analysis is to evaluate the eff... A network meta-analysis was conducted using a predetermined protocol after searching the electronic databases MEDLINE, Scopus, the Cochrane Library and US National Institutes of Health Ongoing Trials ... A total of 10 studies was included in the analysis involving 1331 patients. All but one study controlled for major risk factors, and no differences were observed in patients' baseline characteristics.... Antibiotics mitigate the SSI rate after breast reduction. This meta-analysis provides an evidence-based strategy to optimize antibiotic administration. Further research is needed though to examine ant... This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Inst...