questionsmedicales.fr
Maladies du système immunitaire
Maladies auto-immunes
Maladie de Basedow
Ophtalmopathie basedowienne
Ophtalmopathie basedowienne : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Ophtalmopathie
Maladie de Basedow
Thyroïdite
Imagerie par résonance magnétique
Échographie
Thyroïde
Exophtalmie
Diplopie
Paupière
Hormones thyroïdiennes
Anticorps
Thyroïde
Diagnostic différentiel
Exophtalmie
Maladies oculaires
Symptômes
5
Exophtalmie
Sécheresse oculaire
Douleur oculaire
Diplopie
Muscles oculaires
Vision
Vision
Vision floue
Troubles visuels
Paupières
Inflammation
Gonflement
Symptômes
Variabilité
Maladie
Prévention
5
Prévention
Maladie de Basedow
Thyroïde
Tabagisme
Risque
Symptômes
Stress
Gestion du stress
Santé
Examens médicaux
Détection précoce
Santé oculaire
Alimentation
Santé thyroïdienne
Santé oculaire
Traitements
5
Corticostéroïdes
Radiothérapie
Chirurgie
Corticostéroïdes
Inflammation
Symptômes
Chirurgie
Exophtalmie
Vision
Radiothérapie
Tissus orbitaires
Inflammation
Larmes artificielles
Lunettes prismatiques
Traitements non médicamenteux
Complications
5
Complications
Perte de vision
Nerfs optiques
Perte de vision
Récupération
Gravité
Esthétique
Exophtalmie
Paupières
Nerfs optiques
Inflammation
Vision
Complications
Suivi médical
Traitement
Facteurs de risque
5
Facteurs de risque
Hyperthyroïdie
Antécédents familiaux
Antécédents familiaux
Maladies thyroïdiennes
Risque
Stress
Facteurs de risque
Symptômes
Femmes
Risque
Ophtalmopathie
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Ophtalmopathie basedowienne : Questions médicales les plus fréquentes",
"headline": "Ophtalmopathie basedowienne : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Ophtalmopathie basedowienne : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-26",
"dateModified": "2025-03-23",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Ophtalmopathie basedowienne"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Maladie de Basedow",
"url": "https://questionsmedicales.fr/mesh/D006111",
"about": {
"@type": "MedicalCondition",
"name": "Maladie de Basedow",
"code": {
"@type": "MedicalCode",
"code": "D006111",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C20.111.555"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Ophtalmopathie basedowienne",
"alternateName": "Graves Ophthalmopathy",
"code": {
"@type": "MedicalCode",
"code": "D049970",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Kubra Serbest Ceylanoglu",
"url": "https://questionsmedicales.fr/author/Kubra%20Serbest%20Ceylanoglu",
"affiliation": {
"@type": "Organization",
"name": "University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey."
}
},
{
"@type": "Person",
"name": "Emine Malkoc Sen",
"url": "https://questionsmedicales.fr/author/Emine%20Malkoc%20Sen",
"affiliation": {
"@type": "Organization",
"name": "University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey."
}
},
{
"@type": "Person",
"name": "Xin Wang",
"url": "https://questionsmedicales.fr/author/Xin%20Wang",
"affiliation": {
"@type": "Organization",
"name": "School of Basic Medical Science, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, 563000, China."
}
},
{
"@type": "Person",
"name": "Poupak Fallahi",
"url": "https://questionsmedicales.fr/author/Poupak%20Fallahi",
"affiliation": {
"@type": "Organization",
"name": "Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy."
}
},
{
"@type": "Person",
"name": "Alessandro Antonelli",
"url": "https://questionsmedicales.fr/author/Alessandro%20Antonelli",
"affiliation": {
"@type": "Organization",
"name": "Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms.",
"datePublished": "2023-05-16",
"url": "https://questionsmedicales.fr/article/37194281",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1080/0284186X.2023.2212411"
}
},
{
"@type": "ScholarlyArticle",
"name": "Lung neuroendocrine neoplasms: a single centre surgical series and analysis of staging.",
"datePublished": "2023-04-27",
"url": "https://questionsmedicales.fr/article/37106553",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1111/ans.18493"
}
},
{
"@type": "ScholarlyArticle",
"name": "Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies.",
"datePublished": "2022-10-28",
"url": "https://questionsmedicales.fr/article/36307533",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1038/s41571-022-00696-0"
}
},
{
"@type": "ScholarlyArticle",
"name": "Role of Bone Metastases in Lung Neuroendocrine Neoplasms: Clinical Presentation, Treatment and Impact on Prognosis.",
"datePublished": "2024-08-17",
"url": "https://questionsmedicales.fr/article/39201642",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms25168957"
}
},
{
"@type": "ScholarlyArticle",
"name": "Expression patterns of novel immunotherapy targets in intermediate- and high-grade lung neuroendocrine neoplasms.",
"datePublished": "2024-05-02",
"url": "https://questionsmedicales.fr/article/38693435",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s00262-024-03704-7"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies du système immunitaire",
"item": "https://questionsmedicales.fr/mesh/D007154"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies auto-immunes",
"item": "https://questionsmedicales.fr/mesh/D001327"
},
{
"@type": "ListItem",
"position": 4,
"name": "Maladie de Basedow",
"item": "https://questionsmedicales.fr/mesh/D006111"
},
{
"@type": "ListItem",
"position": 5,
"name": "Ophtalmopathie basedowienne",
"item": "https://questionsmedicales.fr/mesh/D049970"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Ophtalmopathie basedowienne - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Ophtalmopathie basedowienne",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-03",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Ophtalmopathie basedowienne",
"description": "Comment diagnostiquer l'ophtalmopathie de Basedow ?\nQuels examens sont utilisés pour le diagnostic ?\nQuels signes cliniques indiquent cette maladie ?\nLes tests sanguins sont-ils nécessaires ?\nPeut-on confondre cette maladie avec d'autres ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Ophtalmopathie basedowienne",
"description": "Quels sont les symptômes courants ?\nLa diplopie est-elle fréquente ?\nY a-t-il des changements dans la vision ?\nComment se manifeste l'inflammation des paupières ?\nLes symptômes peuvent-ils varier d'une personne à l'autre ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Ophtalmopathie basedowienne",
"description": "Peut-on prévenir l'ophtalmopathie de Basedow ?\nLe tabagisme influence-t-il la maladie ?\nComment gérer le stress pour prévenir la maladie ?\nLes examens réguliers sont-ils importants ?\nUne alimentation saine peut-elle aider ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Ophtalmopathie basedowienne",
"description": "Quels traitements sont disponibles ?\nLes corticostéroïdes sont-ils efficaces ?\nQuand la chirurgie est-elle nécessaire ?\nLa radiothérapie est-elle courante ?\nY a-t-il des traitements non médicamenteux ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Ophtalmopathie basedowienne",
"description": "Quelles sont les complications possibles ?\nLa perte de vision est-elle réversible ?\nQuels problèmes esthétiques peuvent survenir ?\nLes nerfs optiques peuvent-ils être affectés ?\nY a-t-il des risques de complications après traitement ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Ophtalmopathie basedowienne",
"description": "Quels sont les principaux facteurs de risque ?\nL'âge influence-t-il le risque ?\nLes antécédents familiaux jouent-ils un rôle ?\nLe stress peut-il être un facteur de risque ?\nLes femmes sont-elles plus à risque ?",
"url": "https://questionsmedicales.fr/mesh/D049970?mesh_terms=Lung+Neoplasms#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer l'ophtalmopathie de Basedow ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen clinique, l'imagerie et des tests sanguins pour évaluer la fonction thyroïdienne."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les examens incluent l'échographie oculaire, l'IRM et les tests de la fonction thyroïdienne."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques indiquent cette maladie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes incluent l'exophtalmie, la diplopie, et des modifications de la paupière."
}
},
{
"@type": "Question",
"name": "Les tests sanguins sont-ils nécessaires ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils permettent de mesurer les niveaux d'hormones thyroïdiennes et d'anticorps."
}
},
{
"@type": "Question",
"name": "Peut-on confondre cette maladie avec d'autres ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut être confondue avec d'autres causes d'exophtalmie, nécessitant un diagnostic différentiel."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes courants ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent l'exophtalmie, la sécheresse oculaire, et des douleurs oculaires."
}
},
{
"@type": "Question",
"name": "La diplopie est-elle fréquente ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la diplopie est un symptôme courant, causée par l'atteinte des muscles oculaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des changements dans la vision ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des changements visuels peuvent survenir, y compris une vision floue ou double."
}
},
{
"@type": "Question",
"name": "Comment se manifeste l'inflammation des paupières ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation peut entraîner un gonflement, une rougeur et une rétraction des paupières."
}
},
{
"@type": "Question",
"name": "Les symptômes peuvent-ils varier d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'intensité et la combinaison des symptômes peuvent varier considérablement."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'ophtalmopathie de Basedow ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de méthode de prévention spécifique, mais contrôler la thyroïde peut aider."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il la maladie ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme aggrave les symptômes et augmente le risque d'ophtalmopathie."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour prévenir la maladie ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion du stress peut aider à réduire les poussées de la maladie et améliorer la santé globale."
}
},
{
"@type": "Question",
"name": "Les examens réguliers sont-ils importants ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des examens réguliers permettent de détecter précocement les signes de la maladie."
}
},
{
"@type": "Question",
"name": "Une alimentation saine peut-elle aider ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé thyroïdienne et oculaire."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent les corticostéroïdes, la radiothérapie et la chirurgie dans les cas graves."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils réduisent l'inflammation et améliorent les symptômes oculaires."
}
},
{
"@type": "Question",
"name": "Quand la chirurgie est-elle nécessaire ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie est envisagée pour corriger l'exophtalmie sévère ou les problèmes de vision."
}
},
{
"@type": "Question",
"name": "La radiothérapie est-elle courante ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est utilisée pour traiter l'inflammation sévère des tissus orbitaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements non médicamenteux ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements non médicamenteux incluent des larmes artificielles et des lunettes prismatiques."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent la perte de vision, l'atteinte des nerfs optiques et des problèmes esthétiques."
}
},
{
"@type": "Question",
"name": "La perte de vision est-elle réversible ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cela dépend de la gravité de l'atteinte; certaines pertes peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Quels problèmes esthétiques peuvent survenir ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes esthétiques incluent l'exophtalmie et des modifications des paupières."
}
},
{
"@type": "Question",
"name": "Les nerfs optiques peuvent-ils être affectés ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'inflammation peut entraîner une compression des nerfs optiques, affectant la vision."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de complications après traitement ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications peuvent survenir même après un traitement, nécessitant un suivi."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'hyperthyroïdie, le tabagisme et des antécédents familiaux."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque augmente généralement avec l'âge, surtout chez les femmes de 30 à 50 ans."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un historique familial de maladies thyroïdiennes augmente le risque d'ophtalmopathie."
}
},
{
"@type": "Question",
"name": "Le stress peut-il être un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut déclencher ou aggraver les symptômes de l'ophtalmopathie."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes sont plus souvent touchées par l'ophtalmopathie de Basedow que les hommes."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 23/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.
Publications dans "Ophtalmopathie basedowienne" :
4 publications dans cette catégorie
Affiliations :
University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
School of Basic Medical Science, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, 563000, China.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Endocrinology and Metabolism, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde), Foshan, China.
The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Biomedical Commercialization Center, Taipei Medical University, Taipei 11031, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
School of Medicine, National Yang Ming University, Taipei 11221, Taiwan.
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Laboratory of Biochemistry and Clinical Chemistry at the Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Chair and Department of Biochemistry, First Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Chair and Department of Biochemistry, First Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Yuelu District, 138 Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Yuelu District, 138 Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China. weixiong420@csu.edu.cn.
Publications dans "Ophtalmopathie basedowienne" :
Lung neuroendocrine neoplasms (NEN) are a heterogeneous population of neoplasms with different pathology, clinical behavior, and prognosis compared to the more common lung cancers. The diagnostic work...
To review the outcomes of surgically resected lung neuroendocrine neoplasms (LNEN) at a tertiary referral centre and to validate a previously published LNEN-specific staging system (NETL)....
All patients who were identified on histopathology to have LNEN were included. Pre-, intra- and post-operative outcomes were collected, including long-term survival. Patients were staged by both the T...
A total of 132 patients were included in the study, with a median age of 65 years; 55% were female. Typical carcinoid (TC) was the most common pathology (53.4%) followed by large cell neuroendocrine c...
This is the largest known Australian series of LNEN to date, showing survival comparable to international outcomes. We have demonstrated large variations in outcome, driven by histological grade. The ...
Neuroendocrine neoplasms (NENs) can develop in almost any organ and span a spectrum from well-differentiated and indolent neuroendocrine tumours (NETs) to poorly differentiated and highly aggressive n...
Lung neuroendocrine neoplasms (L-NEN) are heterogeneous tumors. While bone metastases (BM) have been associated with worse prognosis in other NEN, their role in L-NEN deserves in-depth analysis. This ...
Advancements in immunotherapeutic approaches only had a modest impact on the therapy of lung neuroendocrine neoplasms (LNENs). Our multicenter study aimed to investigate the expression patterns of nov...
The expressions of V-domain Ig suppressor of T cell activation (VISTA), OX40L, Glucocorticoid-induced TNF receptor (GITR), and T cell immunoglobulin and mucin domain 3 (TIM3) proteins were measured by...
Tumor cell TIM3 expression was the highest in ACs (p < 0.001), whereas elevated tumor cell GITR levels were characteristic for both ACs and SCLCs (p < 0.001 and p = 0.011, respectively). OX40L express...
LNEN subtypes have characteristic and widely divergent VISTA, OX40L, GITR, and TIM3 protein expressions. By shedding light on the different expression patterns of these immunotherapy targets, the curr...
Although immunotherapy has led to a paradigm shift in the treatment of lung cancer, the therapeutic approaches for lung neuroendocrine neoplasms (LNENs) are still limited. Our aim was to explore the i...
Surgically removed tumor samples of 26 atypical carcinoid (AC), 30 large cell neuroendocrine carcinoma (LCNEC) and 29 small cell lung cancer (SCLC) patients were included. The immune phenotype of each...
Unsupervised hierarchical clustering revealed distinct immunologic profiles across tumor types. Specifically, AC tumors were characterized by high tumor cell CD40 expression and low levels of immune i...
By providing insights into the widely divergent immunologic profiles of LNENs, our results might serve as a basis for the development of novel immunotherapy-related approaches in these devastating mal...
Enhanced recovery after surgery programs have reduced complications and shortened hospital stays after lung resection. This study aimed to determine whether video-assisted thoracoscopic surgery perfor...
This retrospective, propensity-matched, cohort analysis was conducted from January 2020 to August 2020. Among 959 patients who underwent video-assisted thoracoscopic surgery, 739 underwent inpatient s...
Propensity matching estimated 218 patients in each group. The mean length of hospital stay was shorter in the two-day surgery group (2.17 ± 0.89 days) than in the inpatient surgery group (6.31 ± 2.13 ...
Two-day surgery is a safe, feasible, and cost-effective procedure for selected patients with lung neoplasms when combined with accurate preoperative evaluations, successful intraoperative assessments,...
Recently, advancement of somatostatin receptor (SSTR) imaging and theragnostic approach using peptide receptor radionuclide therapy (PRRT) have changed the paradigm of diagnosis and management of neur...
Metastasis to the thyroid gland is very uncommon with an incidence of 2-3% of all thyroid malignancies. A higher incidence is noted in autopsy studies indicating incidental detection. However, tumour-...
The roles of cyclin-dependent kinase 6 (CDK6) in various cancers, including small cell lung carcinoma (SCLC), remain unclear. Here, 111,54 multi-center samples were investigated to determine the expre...