Titre : Syndécane-2

Syndécane-2 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Ossicular Replacement
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recommandés pour le Syndécane-2 ?\nLe dosage sanguin est-il utile pour le Syndécane-2 ?\nQuels marqueurs sont associés au Syndécane-2 ?\nY a-t-il des tests spécifiques pour le Syndécane-2 ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Syndécane-2", "description": "Quels symptômes sont liés à une dysfonction de Syndécane-2 ?\nLe Syndécane-2 affecte-t-il la croissance tumorale ?\nY a-t-il des signes cliniques associés au Syndécane-2 ?\nLe Syndécane-2 est-il lié à des maladies spécifiques ?\nComment le Syndécane-2 influence-t-il la signalisation cellulaire ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Syndécane-2", "description": "Peut-on prévenir les anomalies de Syndécane-2 ?\nY a-t-il des mesures préventives spécifiques ?\nL'alimentation influence-t-elle le Syndécane-2 ?\nLe tabagisme affecte-t-il le Syndécane-2 ?\nL'exercice physique a-t-il un impact sur le Syndécane-2 ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Syndécane-2", "description": "Quels traitements ciblent le Syndécane-2 ?\nLe Syndécane-2 peut-il être une cible thérapeutique ?\nY a-t-il des médicaments associés au Syndécane-2 ?\nComment les thérapies géniques affectent-elles le Syndécane-2 ?\nLe Syndécane-2 est-il impliqué dans des essais cliniques ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Syndécane-2", "description": "Quelles complications peuvent survenir avec le Syndécane-2 ?\nLe Syndécane-2 est-il lié à des complications cardiovasculaires ?\nComment le Syndécane-2 affecte-t-il la réponse immunitaire ?\nY a-t-il des complications liées à la thérapie ciblée du Syndécane-2 ?\nLe Syndécane-2 influence-t-il la progression des maladies ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Syndécane-2", "description": "Quels sont les facteurs de risque pour le Syndécane-2 ?\nL'âge influence-t-il le Syndécane-2 ?\nLe stress a-t-il un impact sur le Syndécane-2 ?\nY a-t-il des prédispositions génétiques au Syndécane-2 ?\nL'environnement joue-t-il un rôle dans le Syndécane-2 ?", "url": "https://questionsmedicales.fr/mesh/D053669?mesh_terms=Ossicular+Replacement&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une anomalie de Syndécane-2 ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests génétiques et des analyses de tissus peuvent être utilisés pour évaluer les niveaux de Syndécane-2." } }, { "@type": "Question", "name": "Quels examens sont recommandés pour le Syndécane-2 ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des biopsies et des analyses immunohistochimiques peuvent aider à diagnostiquer les anomalies." } }, { "@type": "Question", "name": "Le dosage sanguin est-il utile pour le Syndécane-2 ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Le dosage sanguin peut fournir des informations sur les niveaux de Syndécane-2 dans certaines conditions." } }, { "@type": "Question", "name": "Quels marqueurs sont associés au Syndécane-2 ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des marqueurs tumoraux et des cytokines peuvent être associés à l'expression de Syndécane-2." } }, { "@type": "Question", "name": "Y a-t-il des tests spécifiques pour le Syndécane-2 ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des tests spécifiques d'immunofluorescence peuvent être utilisés pour détecter Syndécane-2." } }, { "@type": "Question", "name": "Quels symptômes sont liés à une dysfonction de Syndécane-2 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes peuvent inclure des troubles de l'adhésion cellulaire et des anomalies tissulaires." } }, { "@type": "Question", "name": "Le Syndécane-2 affecte-t-il la croissance tumorale ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une expression anormale de Syndécane-2 peut influencer la croissance et la métastase tumorale." } }, { "@type": "Question", "name": "Y a-t-il des signes cliniques associés au Syndécane-2 ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des signes cliniques peuvent inclure des inflammations et des modifications dans la matrice extracellulaire." } }, { "@type": "Question", "name": "Le Syndécane-2 est-il lié à des maladies spécifiques ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il est impliqué dans des maladies comme le cancer et certaines maladies inflammatoires." } }, { "@type": "Question", "name": "Comment le Syndécane-2 influence-t-il la signalisation cellulaire ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Il modifie la signalisation cellulaire en interagissant avec des récepteurs et des ligands." } }, { "@type": "Question", "name": "Peut-on prévenir les anomalies de Syndécane-2 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention passe par un mode de vie sain et la réduction des facteurs de risque associés." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives spécifiques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des dépistages réguliers et une surveillance des maladies associées peuvent aider à la prévention." } }, { "@type": "Question", "name": "L'alimentation influence-t-elle le Syndécane-2 ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée peut influencer l'expression de Syndécane-2 et la santé cellulaire." } }, { "@type": "Question", "name": "Le tabagisme affecte-t-il le Syndécane-2 ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le tabagisme peut altérer l'expression de Syndécane-2 et augmenter le risque de maladies." } }, { "@type": "Question", "name": "L'exercice physique a-t-il un impact sur le Syndécane-2 ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "L'exercice régulier peut améliorer la santé cellulaire et potentiellement réguler Syndécane-2." } }, { "@type": "Question", "name": "Quels traitements ciblent le Syndécane-2 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des thérapies ciblées et des anticorps monoclonaux peuvent être développés pour cibler Syndécane-2." } }, { "@type": "Question", "name": "Le Syndécane-2 peut-il être une cible thérapeutique ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, en raison de son rôle dans la progression tumorale, il est une cible potentielle pour des traitements." } }, { "@type": "Question", "name": "Y a-t-il des médicaments associés au Syndécane-2 ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Des médicaments expérimentaux ciblant la signalisation de Syndécane-2 sont en développement." } }, { "@type": "Question", "name": "Comment les thérapies géniques affectent-elles le Syndécane-2 ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Les thérapies géniques peuvent corriger les anomalies d'expression de Syndécane-2 dans certaines pathologies." } }, { "@type": "Question", "name": "Le Syndécane-2 est-il impliqué dans des essais cliniques ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des essais cliniques évaluent des traitements ciblant Syndécane-2 dans divers cancers." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec le Syndécane-2 ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des troubles de la cicatrisation et des métastases dans le cancer." } }, { "@type": "Question", "name": "Le Syndécane-2 est-il lié à des complications cardiovasculaires ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des études suggèrent un lien entre Syndécane-2 et des complications cardiovasculaires." } }, { "@type": "Question", "name": "Comment le Syndécane-2 affecte-t-il la réponse immunitaire ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Une dysfonction de Syndécane-2 peut altérer la réponse immunitaire, augmentant le risque d'infections." } }, { "@type": "Question", "name": "Y a-t-il des complications liées à la thérapie ciblée du Syndécane-2 ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des effets secondaires peuvent survenir avec les thérapies ciblées, nécessitant une surveillance." } }, { "@type": "Question", "name": "Le Syndécane-2 influence-t-il la progression des maladies ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une expression anormale peut accélérer la progression de certaines maladies, comme le cancer." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour le Syndécane-2 ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des prédispositions génétiques, le tabagisme et l'obésité." } }, { "@type": "Question", "name": "L'âge influence-t-il le Syndécane-2 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'âge peut affecter l'expression de Syndécane-2 et le risque de maladies associées." } }, { "@type": "Question", "name": "Le stress a-t-il un impact sur le Syndécane-2 ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Le stress chronique peut influencer l'expression de Syndécane-2 et la santé cellulaire." } }, { "@type": "Question", "name": "Y a-t-il des prédispositions génétiques au Syndécane-2 ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines mutations génétiques peuvent augmenter le risque d'anomalies de Syndécane-2." } }, { "@type": "Question", "name": "L'environnement joue-t-il un rôle dans le Syndécane-2 ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des toxines environnementales peut affecter l'expression de Syndécane-2." } } ] } ] }

Sources (6940 au total)

Fascial Arthroplastic Ossiculoplasty - A New Technique of Ossicular Reconstruction.

Ossicular reconstruction with autologous materials has been practised for a long time, but the procedure may lead to stiffness of joints and bony ankyloses thus hampering the sound conduction mechanis... This study is a prospective study of 35 patients requiring tympanomastoid surgery with ossicular reconstruction and were studied over a period of 2 years. The newly reconstructed ossicular joints were... A significant air-bone gap closure was achieved in 23 patients, while moderate improvement was seen in remaining cases. Only 1 patient had tympanic membrane graft failure and rest all had well healed ... Fascial arthroplastic ossiculoplasty is a simple and safe procedure and the results are reproducible and more predictable. It provides an ossicular assembly which is near to normal in its physiologica...

Effects of preloads on middle-ear transfer function and acoustic reflex in ossiculoplasty with PORP.

Surgical outcomes in ossiculoplasty with partial ossicular replacement prostheses (PORPs) are greatly influenced by the amount of preload imposed on the PORP. In this study, the attenuation of the mid... The experiments were performed on fresh-frozen human cadaveric temporal bones. The effect of preloads along different directions were experimentally assessed by simulating anatomical variance and post... The preloads as well as the stapedial muscle tension primarily attenuated the METF between 0.5 and 4 kHz. The largest attenuations resulted from the preload towards the medial direction. The attenuati... The experimental study of the preload effects indicates a direction-dependent attenuation of the METF, with the most pronounced effects resulting from preloads towards the medial direction. Based on t...

Primary ossiculoplasties provide better hearing results than revisions: a retrospective cohort study.

To evaluate the efficacy of ossicular chain reconstruction (OCR) in primary and revision surgeries, and to investigate the impact of the number of previous surgeries on hearing outcomes.... Retrospective analysis of cases with OCR due to chronic otitis in a tertiary center between January 2018 and September 2021.... Altogether, 147 cases of ossicle involvement were assessed. In 91.83% (n = 135) OCR was performed, 96.26% of them with titanium TORP/PORP (n = 130), two cases with autologous prosthesis and three with... Titanium prostheses are effective in OCR both in primary and revision cases. It is not the number of previous surgeries, but the fact of revision that influences postoperative hearing results....

Audiometric Outcomes Comparing Endoscopic Versus Microscopic Ossiculoplasty.

To assess endoscopic and microscopic ossiculoplasty audiometric outcomes.... Retrospective review.... Tertiary academic center.... Adult patients who underwent ossiculoplasty with either partial ossicular replacement prosthesis (PORP) or total ossicular replacement prosthesis (TORP) from 2010 to 2019 with at least 1 year of audio... Endoscopic or microscopic ossiculoplasty.... Postoperative air-bone gap (ABG) after at least 1 year.... A total of 198 patients, 53.5% female, and a median age of 47.5 years, met inclusion criteria. 64.1% of patients were reconstructed with a PORP, and 31.8% were reconstructed using an endoscopic approa... For PORP ossiculoplasty procedures, endoscopic ossiculoplasty is associated with improved postoperative ABG compared with microscopic ossiculoplasty....

Endoscopic transcanal management of incus long process defects: rebridging with bone cement versus incus interposition.

to compare hearing outcomes between endoscopic transcanal rebridging with bone cement and endoscopic transcanal incus interposition in patients with incus long process defects secondary to chronic sup... This retrospective study was performed on 83 ears of 83 consecutive patients with incus long process defects secondary to chronic suppurative otitis media (inactive mucosal type). According to the ext... Hearing gain (mean ± standard deviation) was 21.39 ± 2.15 dB in group 1 and 19.71 ± 6.12 dB in group 2. A significantly greater hearing gain was achieved in bone cement group than in incus interpositi... Endoscopic transcanal rebridging with bone cement offers greater hearing gain than endoscopic transcanal incus interposition. The two techniques remain reliable and cost-effective techniques in manage...

Which is Better for Ossiculoplasty Following Tympanomastoidectomy: Polycel® or Titanium?

The purpose of this study was to compare the surgical outcomes of Polycel® and titanium in ossiculoplasty following tympanomastoidectomy (TM).... A total of 221 patients underwent ossiculoplasty following TM by a single surgeon using either Polycel® or titanium as prosthesis. Hearing was tested preoperatively and postoperatively at 6 months by ... In canal wall up mastoidectomy (CWUM), both Polycel® and titanium showed favorable successful rates if partial ossicular replacement prosthesis (PORP) was used (64.3% of Polycel® and 67.6% in titanium... Both Polycel® and titanium showed favorable surgical outcomes for ossiculoplasty following CWUM. Titanium prosthesis is recommended for surgery after CWDM....

Real-time monitoring of middle ear prosthesis coupling.

In reconstructive middle ear surgery, acoustic quality has received a high level of attention in recent years. Careful intraoperative selection and positioning of passive middle ear prostheses during ... Laser Doppler vibrometry (LDV) was used to measure the middle ear transfer function (METF) in 18 human temporal bones (TB). The RTM system uses electromagnetic excitation of the OC with a magnet place... Electromagnetic and acoustic excitation of the intact and the reconstructed OC provided comparable METF. The application of the RTM system significantly improved the quality of the OC reconstruction. ... In this TB study, we demonstrated that the quality of OC reconstruction (improved METF as a benchmark for improved transmission) could be significantly increased by means of a RTM system. Intraoperati...

Comparison of endoscopic vs microscopic ossiculoplasty: a study of 157 consecutive cases.

The relatively new technique of trans-canal endoscopic ear surgery (TEES) when compared to microsurgery for ossiculoplasty has advantages of better visualization and no external incision but also has ... Data from a prospective audit of 157 consecutive patients who underwent ossiculoplasty by a single otologist from 2009 to 2018 was analyzed. TEES was introduced in the department in 2014; therefore, a... Of the 157 cases, 50 were TEES and 107 were microsurgery (81 microscope only and 27 combined with endoscope). There was statistically significant improvement (p < 0.001) in AC (43.4 dB pre-operatively... TEES is safe and as effective as microsurgery in ossiculoplasty with possibly much less pain and morbidity....

Wideband frequency impedance for diagnosis of ossicular chain abnormality.

The accurate estimation of the ossicular chain abnormalities using existing functional examinations has been difficult.... This study aimed to verify the accuracy of preoperative diagnosis of ossicular chain abnormalities using a wideband frequency impedance (WFI) meter, which can measure the dynamic characteristics of th... Retrospective cohort study. Fourteen ears of patients with ossicular chain abnormalities that were definitively diagnosed surgically were included in this study. The following data were collected for ... The SPL curve obtained using the WFI meter had lesser noise than that obtained using the SFI meter. The distribution map revealed that the ossicular chain separation range and ossicular chain fixation... WFI can potentially enhance the accuracy of SFI. In addition, it can also be used for the classification of ossicular chain separation and fixation as well as the quantification of fixation in cases o...