questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Glycoprotéines membranaires
Syndécanes
Syndécane-2
Syndécane-2 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Syndécane-2
Tests génétiques
Biopsie
Immunohistochimie
Dosage sanguin
Syndécane-2
Marqueurs tumoraux
Cytokines
Immunofluorescence
Syndécane-2
Symptômes
5
Dysfonction cellulaire
Anomalies tissulaires
Croissance tumorale
Métastase
Inflammation
Matrice extracellulaire
Cancer
Maladies inflammatoires
Signalisation cellulaire
Récepteurs
Prévention
5
Prévention
Facteurs de risque
Alimentation
Santé cellulaire
Tabagisme
Risque de maladies
Exercice physique
Santé cellulaire
Traitements
5
Thérapies ciblées
Anticorps monoclonaux
Cible thérapeutique
Progression tumorale
Médicaments expérimentaux
Signalisation
Thérapies géniques
Anomalies d'expression
Complications
5
Complications
Cicatrisation
Complications cardiovasculaires
Syndécane-2
Réponse immunitaire
Infections
Thérapie ciblée
Effets secondaires
Progression des maladies
Cancer
Facteurs de risque
5
Facteurs de risque
Obésité
Prédispositions génétiques
Mutations
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie de Syndécane-2 ?",
"position": 1,
"acceptedAnswer": {
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"text": "Des tests génétiques et des analyses de tissus peuvent être utilisés pour évaluer les niveaux de Syndécane-2."
}
},
{
"@type": "Question",
"name": "Quels examens sont recommandés pour le Syndécane-2 ?",
"position": 2,
"acceptedAnswer": {
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"text": "Des biopsies et des analyses immunohistochimiques peuvent aider à diagnostiquer les anomalies."
}
},
{
"@type": "Question",
"name": "Le dosage sanguin est-il utile pour le Syndécane-2 ?",
"position": 3,
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{
"@type": "Question",
"name": "Quels marqueurs sont associés au Syndécane-2 ?",
"position": 4,
"acceptedAnswer": {
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"text": "Des marqueurs tumoraux et des cytokines peuvent être associés à l'expression de Syndécane-2."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests spécifiques pour le Syndécane-2 ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests spécifiques d'immunofluorescence peuvent être utilisés pour détecter Syndécane-2."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à une dysfonction de Syndécane-2 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des troubles de l'adhésion cellulaire et des anomalies tissulaires."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 affecte-t-il la croissance tumorale ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une expression anormale de Syndécane-2 peut influencer la croissance et la métastase tumorale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques associés au Syndécane-2 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes cliniques peuvent inclure des inflammations et des modifications dans la matrice extracellulaire."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 est-il lié à des maladies spécifiques ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il est impliqué dans des maladies comme le cancer et certaines maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "Comment le Syndécane-2 influence-t-il la signalisation cellulaire ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il modifie la signalisation cellulaire en interagissant avec des récepteurs et des ligands."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les anomalies de Syndécane-2 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par un mode de vie sain et la réduction des facteurs de risque associés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages réguliers et une surveillance des maladies associées peuvent aider à la prévention."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle le Syndécane-2 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut influencer l'expression de Syndécane-2 et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il le Syndécane-2 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut altérer l'expression de Syndécane-2 et augmenter le risque de maladies."
}
},
{
"@type": "Question",
"name": "L'exercice physique a-t-il un impact sur le Syndécane-2 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exercice régulier peut améliorer la santé cellulaire et potentiellement réguler Syndécane-2."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent le Syndécane-2 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des anticorps monoclonaux peuvent être développés pour cibler Syndécane-2."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 peut-il être une cible thérapeutique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, en raison de son rôle dans la progression tumorale, il est une cible potentielle pour des traitements."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments associés au Syndécane-2 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments expérimentaux ciblant la signalisation de Syndécane-2 sont en développement."
}
},
{
"@type": "Question",
"name": "Comment les thérapies géniques affectent-elles le Syndécane-2 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les thérapies géniques peuvent corriger les anomalies d'expression de Syndécane-2 dans certaines pathologies."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 est-il impliqué dans des essais cliniques ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des essais cliniques évaluent des traitements ciblant Syndécane-2 dans divers cancers."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le Syndécane-2 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des troubles de la cicatrisation et des métastases dans le cancer."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 est-il lié à des complications cardiovasculaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre Syndécane-2 et des complications cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Comment le Syndécane-2 affecte-t-il la réponse immunitaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une dysfonction de Syndécane-2 peut altérer la réponse immunitaire, augmentant le risque d'infections."
}
},
{
"@type": "Question",
"name": "Y a-t-il des complications liées à la thérapie ciblée du Syndécane-2 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des effets secondaires peuvent survenir avec les thérapies ciblées, nécessitant une surveillance."
}
},
{
"@type": "Question",
"name": "Le Syndécane-2 influence-t-il la progression des maladies ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une expression anormale peut accélérer la progression de certaines maladies, comme le cancer."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour le Syndécane-2 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques, le tabagisme et l'obésité."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le Syndécane-2 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge peut affecter l'expression de Syndécane-2 et le risque de maladies associées."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur le Syndécane-2 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut influencer l'expression de Syndécane-2 et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques au Syndécane-2 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines mutations génétiques peuvent augmenter le risque d'anomalies de Syndécane-2."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle dans le Syndécane-2 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines environnementales peut affecter l'expression de Syndécane-2."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/02/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Department of Life Sciences, College of Natural Sciences, Ewha Womans University, Seoul 03760, Korea.
6 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
6 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
5 publications dans cette catégorie
Affiliations :
Department of Life Sciences, College of Natural Sciences, Ewha Womans University, Seoul 03760, Korea.
Publications dans "Syndécane-2" :
5 publications dans cette catégorie
Affiliations :
Department of Medicine, Albert Szent-Györgyi Clinical Center, Faculty of Medicine, University of Szeged, H-6725 Szeged, Hungary.
Publications dans "Syndécane-2" :
4 publications dans cette catégorie
Affiliations :
Department of Life Sciences, College of Natural Sciences, Ewha Womans University, Seoul 03760, Korea.
Publications dans "Syndécane-2" :
4 publications dans cette catégorie
Affiliations :
Department of Life Sciences, Ewha Womans University, Seoul, South Korea.
Research Center for Cellular Homeostasis, Ewha Womans University, Seoul, South Korea.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research and Oslo University Hospital, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research and Oslo University Hospital, University of Oslo, Oslo, Norway.
K.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research and Oslo University Hospital, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
PCG-Biotech, Ltd., Yonsei Engineering Research Park 114A, Yonsei University, Yonsei-ro 50, Seoul 03722, Korea.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
PCG-Biotech, Ltd., Yonsei Engineering Research Park 114A, Yonsei University, Yonsei-ro 50, Seoul 03722, Korea.
Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
Szilak Laboratories, Bioinformatics and Molecule-Design, H-6723 Szeged, Hungary.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
1 Division of Pulmonary and Critical Care Medicine, and.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
1 Division of Pulmonary and Critical Care Medicine, and.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
1 Division of Pulmonary and Critical Care Medicine, and.
7 Pulmonary Fibrosis Group, Lovelace Respiratory Research Institute, Albuquerque, New Mexico; and.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
ICBMS, UMR 5246 CNRS - University Lyon 1, Univ Lyon, Villeurbanne, France.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-2" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-2" :
To investigate the vestibular endolymphatic hydrops in patients with semicircular canal malformation....
We searched 7864 patients who underwent MR Imaging after contrast injection and found 21 patients with semicircular canal malformations. Another 9 non-malformed patients with unilateral hearing loss w...
Hearing loss was observed in 18 of 30 malformed ears and in 7 of 12 non-malformed ears. Statistical analysis showed no association between semicircular canal malformation and hearing loss. In the semi...
There was no correlation between semicircular canal malformation and hearing loss. The mean vestibular hydrops volume ratio of the semicircular canal deformed ears with hearing loss was about 22.6%, w...
Intractable benign paroxysmal positional vertigo (BPPV) may be treated by plugging the affected semicircular canal (SCC). A cochlear implant (CI) can diminish subjective symptoms of tinnitus. We prese...
A 50-year-old male experienced single-sided deafness (SSD) with severe ipsilateral tinnitus, and intractable BPPV related to the ipsilateral PSCC. Two years earlier, he had been treated with a bone an...
This is the first case presentation of cochlear implantation performed concurrent to plugging of the ipsilateral PSCC. The outcome of the procedure was overall successful....
The diagnostic characteristics of patients with cupulolithiasis of the posterior semicircular canal are persistent torsional nystagmus in the supine position and persistent torsional nystagmus (opposi...
To investigate the clinical features of posterior cupulolithiasis....
We interviewed 30 consecutive patients with cupulolithiasis of the posterior canal and categorized them by onset time into the following four groups: (1) during sleep; (2) at the time of awakening; (3...
Time of awakening was the most common onset time. The mean disease duration was 18.2 days, and 90% of patients achieved cure within 1 month....
Physicians should take into account the duration of nystagmus, because cupulolithiasis of posterior canal exists. The etiology of posterior cupulolithiasis is closely related to sleep, because time of...
In central as well as peripheral vestibular lesions, right-beating horizontal nystagmus is almost always associated with clockwise (top poles of the eyes beating to the right ear) torsional nystagmus ...
Chronic unsteadiness is a common complaint at vestibular clinics. Bilateral vestibulopathy (BVP) is a major cause of chronic unsteadiness but is often overlooked. Although diagnostic criteria for BVP ...
This study aimed to compare the features of isolated bilateral posterior semicircular canal hypofunction (IBPH) with those of BVP diagnosed based on the Barany criteria....
The clinical data of 8 IBPH patients that had been diagnosed using our diagnostic criteria (sex, age, subjective symptoms, questionnaire, video head-impulse test and stabilometry) were analyzed and co...
The IBPH patients were all aged >70 years, while the age range of the BVP patients was wider. While the BVP patients complained of both oscillopsia during body movement and unsteadiness in darkness, t...
IBPH can cause mild unsteadiness in the elderly....
Clinicians should be aware that IBPH can cause unsteadiness in the elderly....
The study goals were to compare the long-term efficacy of semicircular canal plugging (SCP) with labyrinthectomy in the treatment of advanced Meniere's disease (MD)....
A retrospective study....
Single tertiary medical center....
A total of 116 MD patients (TSCP group of 90; labyrinthectomy group of 26) with complete medical documents in Shandong Provincial ENT Hospital, from March 2017 to March 2019 were retrospectively analy...
The total control rate of vertigo in the TSCP group was 96.7% (87/90). The rate of hearing loss was 23.3% (21/90). The control rate of vertigo in the labyrinthectomy group was 100% (26/26). All patien...
Compared to labyrinthectomy, TSCP can preserve hearing at a high probability; meanwhile, otolith organ function preservation benefits patients from faster vestibular compensation....
3 Laryngoscope, 133:3178-3184, 2023....
Cochlear implant electrode array misplacement is a rare but serious complication that may result in failure of hearing rehabilitation, non-auditory percepts, vestibular disturbance, or damage to adjac...
Superior Semicircular Canal Dehiscence (SSCD) is a dehiscence of the otic capsule which normally lies over the superior semicircular canal. This database constitutes the largest series of SSCD patient...
To determine what preoperative factors, if any, contribute to postoperative outcomes and evaluate symptom resolution in a large SSCD patient cohort....
A single-institution, retrospective chart review collected patient demographics, intraoperative findings, and pre-and postoperative symptoms. Fisher's exact t-test was performed for unpaired categoric...
350 SSCD repairs were performed. The median age was 52 years (range: 17-86 years, ± 6.4 years), and the median follow-up duration was 4.6 months (range: 0.03-59.5 months, ± 6.8 months). Preoperative h...
Surgical repair via the middle cranial fossa approach can significantly resolve auditory, vestibular, and neurological symptoms of patients with SSCD. Although this is one of the largest single-instit...
This study aimed to investigate the incidence of spontaneous nystagmus (SN) in posterior semicircular canal (PSCC) benign paroxysmal positional vertigo (BPPV) and its effect on treatment outcomes....
Retrospective case series....
Tertiary referral center....
This study included 50 patients with idiopathic unilateral PSCC BPPV between July 2021 and May 2022. The presence of SN was investigated, and the results of the bithermal caloric test and video head i...
SN was observed in 13 (26%) of the 50 patients presenting PSCC BPPV. The direction of SN was mainly unidirectional and horizontal in 12 of the 13 patients with a slow-phase velocity ranging from 2 to ...
This study demonstrated that the treatment outcomes of PSCC BPPV were significantly worse in patients with SN than those without SN. Examining the presence of SN in patients with PSCC BPPV may be help...
This case demonstrates the successful identification and treatment of atypical posterior semicircular canal benign paroxysmal positional vertigo (BPPV) based on a unique presentation of positional nys...