questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines et peptides de signalisation intracellulaire
Protein-Serine-Threonine Kinases
Cyclic Nucleotide-Regulated Protein Kinases
Cyclic AMP-Dependent Protein Kinases
Cyclic AMP-Dependent Protein Kinase Type I
Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
Cyclic AMP-Dependent Protein Kinase RIalpha Subunit : Questions médicales fréquentes
Diagnostic
5
Protéines
Analyse génétique
Troubles métaboliques
Croissance
Marqueurs biologiques
Protéines
Symptômes
5
Fatigue
Troubles hormonaux
Douleur
Déséquilibre métabolique
Troubles cognitifs
Humeur
Troubles digestifs
Hormones
Prévention
5
Prévention
Mode de vie sain
Dépistage
Tests génétiques
Exercice
Santé métabolique
Habitudes alimentaires
Nutriments
Suppléments
Consultation médicale
Traitements
5
Thérapie hormonale
Régime alimentaire
Thérapie génique
Recherche
Médicaments
Ciblage thérapeutique
Médecine personnalisée
Traitement
Complications
5
Complications
Métabolisme
Fertilité
Déséquilibres hormonaux
Risques cardiovasculaires
Maladies
Complications psychologiques
Anxiété
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Obésité
Déséquilibres hormonaux
Stress
Signalisation cellulaire
Facteurs environnementaux
Toxiques
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit : Questions médicales les plus fréquentes",
"headline": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Cyclic AMP-Dependent Protein Kinase RIalpha Subunit : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-07-14",
"dateModified": "2026-04-05",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Cyclic AMP-Dependent Protein Kinase Type I",
"url": "https://questionsmedicales.fr/mesh/D054743",
"about": {
"@type": "MedicalCondition",
"name": "Cyclic AMP-Dependent Protein Kinase Type I",
"code": {
"@type": "MedicalCode",
"code": "D054743",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D12.776.476.563.150.125.750"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"alternateName": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"code": {
"@type": "MedicalCode",
"code": "D054756",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Constantine A Stratakis",
"url": "https://questionsmedicales.fr/author/Constantine%20A%20Stratakis",
"affiliation": {
"@type": "Organization",
"name": "Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, USA."
}
},
{
"@type": "Person",
"name": "Byung-Gak Kim",
"url": "https://questionsmedicales.fr/author/Byung-Gak%20Kim",
"affiliation": {
"@type": "Organization",
"name": "Biattic Inc., Anyang 14059, Korea."
}
},
{
"@type": "Person",
"name": "Hwa-Young Youn",
"url": "https://questionsmedicales.fr/author/Hwa-Young%20Youn",
"affiliation": {
"@type": "Organization",
"name": "Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea."
}
},
{
"@type": "Person",
"name": "Ul-Soo Choi",
"url": "https://questionsmedicales.fr/author/Ul-Soo%20Choi",
"affiliation": {
"@type": "Organization",
"name": "Department of Veterinary Clinical Pathology and Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Jeonju 54896, Korea."
}
},
{
"@type": "Person",
"name": "Dong-Ha Bhang",
"url": "https://questionsmedicales.fr/author/Dong-Ha%20Bhang",
"affiliation": {
"@type": "Organization",
"name": "Department of Molecular and Cellular Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 16419, Korea."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic Subunit Beta Activation.",
"datePublished": "2024-06-01",
"url": "https://questionsmedicales.fr/article/38824257",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s10620-024-08481-y"
}
},
{
"@type": "ScholarlyArticle",
"name": "AMP-dependent kinase stimulates the expression of αKlotho.",
"datePublished": "2024-08-01",
"url": "https://questionsmedicales.fr/article/39090792",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1002/2211-5463.13872"
}
},
{
"@type": "ScholarlyArticle",
"name": "Human DNA-dependent protein kinase catalytic subunit deficiency: a comprehensive review and update.",
"datePublished": "2024-07-06",
"url": "https://questionsmedicales.fr/article/38977084",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jaci.2024.06.018"
}
},
{
"@type": "ScholarlyArticle",
"name": "Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases.",
"datePublished": "2024-04-29",
"url": "https://questionsmedicales.fr/article/38732081",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/ijms25094864"
}
},
{
"@type": "ScholarlyArticle",
"name": "Research progress of AMP-activated protein kinase and cardiac aging.",
"datePublished": "2023-08-29",
"url": "https://questionsmedicales.fr/article/37671091",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1515/biol-2022-0710"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Acides aminés, peptides et protéines",
"item": "https://questionsmedicales.fr/mesh/D000602"
},
{
"@type": "ListItem",
"position": 3,
"name": "Protéines",
"item": "https://questionsmedicales.fr/mesh/D011506"
},
{
"@type": "ListItem",
"position": 4,
"name": "Protéines et peptides de signalisation intracellulaire",
"item": "https://questionsmedicales.fr/mesh/D047908"
},
{
"@type": "ListItem",
"position": 5,
"name": "Protein-Serine-Threonine Kinases",
"item": "https://questionsmedicales.fr/mesh/D017346"
},
{
"@type": "ListItem",
"position": 6,
"name": "Cyclic Nucleotide-Regulated Protein Kinases",
"item": "https://questionsmedicales.fr/mesh/D017867"
},
{
"@type": "ListItem",
"position": 7,
"name": "Cyclic AMP-Dependent Protein Kinases",
"item": "https://questionsmedicales.fr/mesh/D017868"
},
{
"@type": "ListItem",
"position": 8,
"name": "Cyclic AMP-Dependent Protein Kinase Type I",
"item": "https://questionsmedicales.fr/mesh/D054743"
},
{
"@type": "ListItem",
"position": 9,
"name": "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"item": "https://questionsmedicales.fr/mesh/D054756"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2026-05-11",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Comment diagnostiquer une anomalie de RIalpha ?\nQuels tests sont utilisés pour évaluer RIalpha ?\nQuels symptômes indiquent un problème avec RIalpha ?\nY a-t-il des marqueurs spécifiques pour RIalpha ?\nComment évaluer l'expression de RIalpha ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Quels symptômes sont liés à une dysfonction de RIalpha ?\nLa dysfonction de RIalpha cause-t-elle des douleurs ?\nY a-t-il des symptômes neurologiques associés ?\nLes symptômes varient-ils selon l'âge ?\nDes symptômes digestifs peuvent-ils être présents ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Comment prévenir les troubles liés à RIalpha ?\nY a-t-il des tests de dépistage recommandés ?\nL'exercice physique aide-t-il à prévenir les troubles ?\nLes habitudes alimentaires influencent-elles RIalpha ?\nDes suppléments sont-ils bénéfiques ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Quels traitements sont disponibles pour les troubles de RIalpha ?\nLa thérapie génique est-elle une option ?\nDes médicaments spécifiques ciblent-ils RIalpha ?\nComment la nutrition influence-t-elle RIalpha ?\nLes traitements sont-ils personnalisés ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Quelles complications peuvent survenir avec RIalpha ?\nLes troubles de RIalpha affectent-ils la fertilité ?\nY a-t-il des risques cardiovasculaires associés ?\nLes complications sont-elles réversibles ?\nDes complications psychologiques peuvent-elles survenir ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Cyclic AMP-Dependent Protein Kinase RIalpha Subunit",
"description": "Quels sont les facteurs de risque pour RIalpha ?\nL'obésité est-elle un facteur de risque ?\nLe stress influence-t-il RIalpha ?\nL'âge est-il un facteur de risque ?\nDes facteurs environnementaux jouent-ils un rôle ?",
"url": "https://questionsmedicales.fr/mesh/D054756#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une anomalie de RIalpha ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques et des analyses biochimiques peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer RIalpha ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests d'activité enzymatique et les dosages d'AMPc sont courants."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème avec RIalpha ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles métaboliques ou des anomalies de croissance peuvent survenir."
}
},
{
"@type": "Question",
"name": "Y a-t-il des marqueurs spécifiques pour RIalpha ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de marqueurs spécifiques largement reconnus."
}
},
{
"@type": "Question",
"name": "Comment évaluer l'expression de RIalpha ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunohistochimie et la PCR en temps réel sont des méthodes efficaces."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à une dysfonction de RIalpha ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, troubles de la croissance et anomalies hormonales peuvent apparaître."
}
},
{
"@type": "Question",
"name": "La dysfonction de RIalpha cause-t-elle des douleurs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des douleurs peuvent survenir en raison de déséquilibres métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques associés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles cognitifs ou des changements d'humeur peuvent être observés."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent se manifester différemment selon l'âge."
}
},
{
"@type": "Question",
"name": "Des symptômes digestifs peuvent-ils être présents ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles digestifs peuvent être liés à des déséquilibres hormonaux."
}
},
{
"@type": "Question",
"name": "Comment prévenir les troubles liés à RIalpha ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests de dépistage recommandés ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent être recommandés pour les familles à risque."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il à prévenir les troubles ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la santé métabolique et hormonale."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles RIalpha ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en nutriments peut soutenir la fonction de RIalpha."
}
},
{
"@type": "Question",
"name": "Des suppléments sont-ils bénéfiques ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments peuvent aider, mais il est important de consulter un médecin."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les troubles de RIalpha ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des thérapies hormonales et des modifications diététiques."
}
},
{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche, mais pas encore largement disponible."
}
},
{
"@type": "Question",
"name": "Des médicaments spécifiques ciblent-ils RIalpha ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de médicaments spécifiquement ciblés sur RIalpha."
}
},
{
"@type": "Question",
"name": "Comment la nutrition influence-t-elle RIalpha ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une nutrition adéquate peut aider à réguler les niveaux d'AMPc et de RIalpha."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction des besoins individuels."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec RIalpha ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications métaboliques et endocriniennes peuvent se développer."
}
},
{
"@type": "Question",
"name": "Les troubles de RIalpha affectent-ils la fertilité ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des déséquilibres hormonaux peuvent impacter la fertilité."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques cardiovasculaires associés ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles métaboliques peuvent augmenter le risque de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié."
}
},
{
"@type": "Question",
"name": "Des complications psychologiques peuvent-elles survenir ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles de l'humeur et de l'anxiété peuvent être liés à RIalpha."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour RIalpha ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux et les déséquilibres hormonaux sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "L'obésité est-elle un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité peut contribuer à des déséquilibres hormonaux affectant RIalpha."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il RIalpha ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut perturber la signalisation de RIalpha."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque de troubles liés à RIalpha augmente avec l'âge."
}
},
{
"@type": "Question",
"name": "Des facteurs environnementaux jouent-ils un rôle ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certains toxiques peut affecter la fonction de RIalpha."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 05/04/2026
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, USA.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Biattic Inc., Anyang 14059, Korea.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Veterinary Clinical Pathology and Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Jeonju 54896, Korea.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular and Cellular Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 16419, Korea.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Medicine, University of Melbourne, Austin Health and St. Vincent's Hospital, Heidelberg, Victoria, Australia.
St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
Mary MacKillop Institute for Health Research, Australian Catholic University, Fitzroy, VIC, Australia.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Research Center for Infectious Diseases, Department of Pathogen Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Hubei Hongshan Laboratory, Wuhan, Hubei Province, China.
Key Laboratory of Preventive Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, Hubei Province, China.
Shenzhen Institute of Nutrition and Health, Huazhong Agricultural University, Shenzhen, Guangdong Province, China.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
INSERM U1016, Institut Cochin, Department of Endocrinology, Metabolism and Diabetes (EMD), 24 rue du faubourg Saint-Jacques, 75014 Paris, France. benoit.viollet@inserm.fr.
CNRS, UMR8104, 75014 Paris, France. benoit.viollet@inserm.fr.
Université Paris Descartes, Sorbonne Paris Cité, 75014 Paris, France. benoit.viollet@inserm.fr.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, U.K.
Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia.
Mary MacKillop Institute for Health Research, Australian Catholic University, 215 Spring Street, Melbourne 3000, Australia.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia.
Mary MacKillop Institute for Health Research, Australian Catholic University, 215 Spring Street, Melbourne 3000, Australia.
The Florey Institute of Neuroscience and Mental Health, Parkville 3052, Australia.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, U.K. Ian.Salt@glasgow.ac.uk.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Laboratorio de Química de Proteínas, Departamento de Biología Celular, Universidad Simón Bolívar, Apartado 89.000, Caracas, 1081-A, Venezuela.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Radioisotope Medicine, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Tumor and Diagnostic Pathology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
2 publications dans cette catégorie
Affiliations :
Department of Radioisotope Medicine, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
Publications dans "Cyclic AMP-Dependent Protein Kinase RIalpha Subunit" :
Previous studies have demonstrated that Dual-specificity phosphatase 4 (DUSP4) plays an important role in the progression of different tumor types. However, the role and mechanism of DUSP4 in colorect...
We investigate the role and mechanisms of DUSP4 in CRC....
Immunohistochemistry was used to investigate DUSP4 expression in CRC tissues. Cell proliferation, apoptosis and migration assays were used to validate DUSP4 function in vitro and in vivo. RNA-sequence...
DUSP4 expression was upregulated in CRC tissues relative to normal colorectal tissues, and DUSP4 expression showed a significant positive correlation with CRC stage. Consistently, we found that DUSP4 ...
These findings suggest that DUSP4 promotes CRC progression. Therefore, it may be a promising therapeutic target for CRC....
Renal αKlotho along with fibroblast growth factor 23 regulates phosphate and vitamin D metabolism. Its cleavage yields soluble Klotho controlling intracellular processes. αKlotho has anti-inflammatory...
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has an essential role in the non-homologous end-joining pathway that repairs DNA double-strand breaks in V(D)J recombination involved in the e...
To provide an update on the genetics, clinical spectrum, immunological profile, and therapy of DNA-PKcs deficiency in human....
The clinical, biological, and treatment data from the 6 cases published to date and from 1 new patient were obtained and analyzed. Rubella PCR was performed on available granuloma material....
We report on 7 patients; Six patients displayed the autosomal recessive p.L3062R mutation in PRKDC gene encoding DNA-PKcs. Atypical severe combined immunodeficiency with inflammatory lesions, granulom...
DNA-PKcs deficiency mainly manifests as an inflammatory disease with granuloma and autoimmune features, along with severe infections....
Flavonoid aglycones are secondary plant metabolites that exhibit a broad spectrum of pharmacological activities, including anti-inflammatory, antioxidant, anticancer, and antiplatelet effects. However...
The process of aging is marked by a gradual deterioration in the physiological functions and functional reserves of various tissues and organs, leading to an increased susceptibility to diseases and e...
The yeast Snf1/AMP-activated kinase (AMPK) maintains energy homeostasis, controlling metabolic processes and glucose derepression in response to nutrient levels and environmental cues. Under condition...
Nuclear factor-kappa B (NF-κB) is a transcriptional factor that binds to the ∼10-base-pair κB motif on target genes and acts as an inflammatory regulator. Since dysregulation of NF-κB is thought to be...
Mycobacterial genomes encode multiple adenylyl cyclases and cAMP effector proteins, underscoring the diverse ways these bacteria utilize cAMP. We identified universal stress proteins (USP), Rv1636, an...
The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status. When activated by increases in ADP:ATP and/or AMP:ATP ratios (signalling energy deficit), AMPK acts to restore energy bal...
Adeno-associated virus 2.5T (AAV2.5T) was selected from the directed evolution of AAV capsid library in human airway epithelia. This study found that recombinant AAV2.5T (rAAV2.5T) transduction of wel...