questionsmedicales.fr
Facteurs biologiques
Marqueurs biologiques
Antigènes de différenciation
Antigènes de différenciation des lymphocytes T
Antigènes CD1
Antigène CD1d
Antigène CD1d : Questions médicales fréquentes
Termes MeSH sélectionnés :
Gene Expression Regulation
Diagnostic
5
Cytométrie en flux
Immunohistochimie
Maladies auto-immunes
Cancer
Analyse sanguine
Antigènes
Récepteurs T
Cellules NKT
Symptômes
5
Infections
Troubles auto-immuns
Réponse immunitaire
Antigènes
Éruptions cutanées
Douleurs articulaires
Troubles neurologiques
Antigènes
Allergies
Réponse immunitaire
Prévention
5
Infections
Santé immunitaire
Nutrition
Fonction immunitaire
Suppléments
Réponse immunitaire
Stress
Fonction immunitaire
Traitements
5
Thérapies immunomodulatrices
Anticorps monoclonaux
Médicaments
Alpha-galactosylceramide
Modulation immunitaire
Antigènes
Thérapie génique
Antigènes
Complications
5
Infections
Maladies auto-immunes
Cancer
Dysfonction immunitaire
Troubles métaboliques
Antigènes
Maladies infectieuses
Antigènes
Facteurs de risque
5
Antécédents familiaux
Maladies auto-immunes
Infections
Réponse immunitaire
Stress
Fonction immunitaire
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"text": "Des tests immunologiques et des analyses de sang peuvent détecter des anomalies de CD1d."
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer CD1d ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunohistochimie et la cytométrie en flux sont couramment utilisés."
}
},
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"@type": "Question",
"name": "CD1d est-il impliqué dans des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
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"text": "Oui, CD1d est associé à des maladies auto-immunes et des cancers."
}
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"@type": "Question",
"name": "Peut-on mesurer CD1d dans le sang ?",
"position": 4,
"acceptedAnswer": {
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"text": "Oui, des tests sanguins peuvent quantifier l'expression de CD1d."
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{
"@type": "Question",
"name": "Quels marqueurs sont associés à CD1d ?",
"position": 5,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Quels symptômes sont liés à une dysfonction de CD1d ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des infections récurrentes et des troubles auto-immuns."
}
},
{
"@type": "Question",
"name": "CD1d affecte-t-il la réponse immunitaire ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une altération de CD1d peut entraîner une réponse immunitaire affaiblie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques spécifiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme des éruptions cutanées ou des douleurs articulaires peuvent apparaître."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques sont-ils liés à CD1d ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre CD1d et des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "CD1d influence-t-il les allergies ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d peut jouer un rôle dans la modulation des réponses allergiques."
}
},
{
"@type": "Question",
"name": "Comment prévenir les dysfonctionnements de CD1d ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain et une vaccination appropriée peuvent aider à prévenir les dysfonctionnements."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les infections et gérer le stress peuvent contribuer à la santé immunitaire."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle CD1d ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la fonction immunitaire et CD1d."
}
},
{
"@type": "Question",
"name": "Les suppléments peuvent-ils aider CD1d ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments, comme les oméga-3, peuvent moduler la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il CD1d ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut altérer la fonction de CD1d et la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent CD1d ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies immunomodulatrices et des anticorps monoclonaux peuvent cibler CD1d."
}
},
{
"@type": "Question",
"name": "CD1d peut-il être une cible pour l'immunothérapie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d est une cible prometteuse pour l'immunothérapie dans certains cancers."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour CD1d ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme l'alpha-galactosylceramide sont en cours d'étude."
}
},
{
"@type": "Question",
"name": "Comment les traitements affectent-ils CD1d ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent moduler l'expression de CD1d et améliorer la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Les thérapies géniques peuvent-elles cibler CD1d ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des approches de thérapie génique sont explorées pour corriger les dysfonctionnements de CD1d."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec CD1d ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections graves et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "CD1d est-il lié à des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une dysfonction de CD1d est associée à un risque accru de certains cancers."
}
},
{
"@type": "Question",
"name": "Les troubles métaboliques sont-ils liés à CD1d ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études montrent un lien potentiel entre CD1d et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de rejet d'organe liés à CD1d ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une altération de CD1d peut augmenter le risque de rejet dans les greffes."
}
},
{
"@type": "Question",
"name": "CD1d influence-t-il les maladies infectieuses ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d joue un rôle dans la susceptibilité aux infections virales et bactériennes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de dysfonction de CD1d ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux de maladies auto-immunes et infections."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il CD1d ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut affecter l'expression et la fonction de CD1d."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il CD1d ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sédentaire et une mauvaise alimentation peuvent nuire à CD1d."
}
},
{
"@type": "Question",
"name": "Les infections antérieures influencent-elles CD1d ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent altérer l'expression de CD1d et la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Le stress psychologique impacte-t-il CD1d ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress psychologique chronique peut affecter la fonction de CD1d."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 01/04/2025
Contenu vérifié selon les dernières recommandations médicales
6 publications dans cette catégorie
Affiliations :
Division of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA, USA.
5 publications dans cette catégorie
Affiliations :
Division of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Publications dans "Antigène CD1d" :
5 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia; cdos@unimelb.edu.au bmoody@bwh.harvard.edu sjwill@unimelb.edu.au dan.pellicci@mcri.edu.au godfrey@unimelb.edu.au.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Publications dans "Antigène CD1d" :
5 publications dans cette catégorie
Affiliations :
Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia; cdos@unimelb.edu.au bmoody@bwh.harvard.edu sjwill@unimelb.edu.au dan.pellicci@mcri.edu.au godfrey@unimelb.edu.au.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Murdoch Children's Research Institute, Parkville, VIC 3052, Australia.
Department of Paediatrics, The University of Melbourne, Parkville, VIC 3052, Australia.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands jj.vandervliet@amsterdamumc.nl.
LAVA Therapeutics, Utrecht, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku , Kyoto , Kyoto 606-8501 , Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan. motohashi@faculty.chiba-u.jp.
Publications dans "Antigène CD1d" :
Skeletal muscle development and regeneration is governed by the combined action of Myf5, MyoD, Mrf4 and MyoG, also known as the myogenic regulatory factors (MRFs). These transcription factors are expr...
Short tandem repeats affect gene expression by binding regulatory proteins....
Regulation of gene expression takes a central place in normal cells to maintain tissue homeostasis but also in cancer cells to respond to intra- and extra-cellular stimuli, such as therapeutic drugs [...
Gene-expression regulation involves multiple processes and a range of regulatory factors. In this review, we describe the key factors that regulate gene expression, including transcription factors (TF...
Viruses have evolved a multitude of mechanisms to combat barriers to productive infection in the host cell. Virally-encoded miRNAs are one such means to regulate host gene expression in ways that bene...
Cellular functions are regulated by signal transduction pathway networks consisting of protein-modifying enzymes that control the activity of many downstream proteins. Protein kinases and phosphatases...
Variation in DNA methylation (DNAm) in adipose tissue is associated with the pathogenesis of obesity and insulin resistance. The activity of enzymes involved in altering DNAm levels is dependent on se...
To understand the role of metabolites as mechanistic regulators of epigenetic marks, we tested the association between selected plasma metabolites and DNAm levels in the adipose tissue of African Amer...
In the AAGMEx cohort (N = 256), plasma levels of metabolites were measured by untargeted liquid chromatography-mass spectrometry; adipose tissue DNAm and transcript levels were measured by reduced rep...
Among the 21 one-carbon metabolism pathway metabolites evaluated, six were associated with gluco-metabolic traits (P...
Our study suggests that a subset of metabolites modulates the methylation levels of CpG sites in specific loci and, in turn, regulates the expression of transcripts involved in obesity and insulin res...
Coronary artery disease (CAD) is the leading cause of death worldwide. Recent meta-analyses of genome-wide association studies have identified over 175 loci associated with CAD. The majority of these ...
We measured gene expression in SMCs isolated from the ascending aortas of 151 heart transplant donors of various genetic ancestries in quiescent or proliferative conditions and calculated the associat...
We identified 4910 expression and 4412 splicing quantitative trait loci (sQTLs) representing regions of the genome associated with transcript abundance and splicing. A total of 3660 expression quantit...
Collectively, our results provide evidence for the molecular mechanisms of genetic susceptibility to CAD in distinct SMC phenotypes....
Cell type- and differentiation-specific gene expression is precisely controlled by genomic non-coding regulatory elements (NCREs), which include promoters, enhancers, silencers and insulators. It is e...
Although gene-expression (GE) and protein levels are typically strongly genetically regulated, their correlation is known to be low. Here we investigate this phenomenon by focusing on the genetic back...
We performed locus-wide association studies of 92 protein levels measured in whole blood for 2,014 samples of European ancestry and found that 66 are genetically regulated. Three female- and one male-...
While total GE and protein levels are only weakly correlated, we found high correlations between their genetically regulated components across multiple tissues. Of note, strong negative causal effects...