questionsmedicales.fr
Facteurs biologiques
Marqueurs biologiques
Antigènes de différenciation
Antigènes de différenciation des lymphocytes T
Antigènes CD1
Antigène CD1d
Antigène CD1d : Questions médicales fréquentes
Termes MeSH sélectionnés :
Hepatitis A Virus Cellular Receptor 2
Diagnostic
5
Cytométrie en flux
Immunohistochimie
Maladies auto-immunes
Cancer
Analyse sanguine
Antigènes
Récepteurs T
Cellules NKT
Symptômes
5
Infections
Troubles auto-immuns
Réponse immunitaire
Antigènes
Éruptions cutanées
Douleurs articulaires
Troubles neurologiques
Antigènes
Allergies
Réponse immunitaire
Prévention
5
Infections
Santé immunitaire
Nutrition
Fonction immunitaire
Suppléments
Réponse immunitaire
Stress
Fonction immunitaire
Traitements
5
Thérapies immunomodulatrices
Anticorps monoclonaux
Médicaments
Alpha-galactosylceramide
Modulation immunitaire
Antigènes
Thérapie génique
Antigènes
Complications
5
Infections
Maladies auto-immunes
Cancer
Dysfonction immunitaire
Troubles métaboliques
Antigènes
Maladies infectieuses
Antigènes
Facteurs de risque
5
Antécédents familiaux
Maladies auto-immunes
Infections
Réponse immunitaire
Stress
Fonction immunitaire
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"name": "Comment diagnostiquer une anomalie de CD1d ?",
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"text": "Des tests immunologiques et des analyses de sang peuvent détecter des anomalies de CD1d."
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},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer CD1d ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunohistochimie et la cytométrie en flux sont couramment utilisés."
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},
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"@type": "Question",
"name": "CD1d est-il impliqué dans des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
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"text": "Oui, CD1d est associé à des maladies auto-immunes et des cancers."
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"@type": "Question",
"name": "Peut-on mesurer CD1d dans le sang ?",
"position": 4,
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{
"@type": "Question",
"name": "Quels marqueurs sont associés à CD1d ?",
"position": 5,
"acceptedAnswer": {
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}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à une dysfonction de CD1d ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des infections récurrentes et des troubles auto-immuns."
}
},
{
"@type": "Question",
"name": "CD1d affecte-t-il la réponse immunitaire ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une altération de CD1d peut entraîner une réponse immunitaire affaiblie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes cliniques spécifiques ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme des éruptions cutanées ou des douleurs articulaires peuvent apparaître."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques sont-ils liés à CD1d ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre CD1d et des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "CD1d influence-t-il les allergies ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d peut jouer un rôle dans la modulation des réponses allergiques."
}
},
{
"@type": "Question",
"name": "Comment prévenir les dysfonctionnements de CD1d ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain et une vaccination appropriée peuvent aider à prévenir les dysfonctionnements."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les infections et gérer le stress peuvent contribuer à la santé immunitaire."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle CD1d ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la fonction immunitaire et CD1d."
}
},
{
"@type": "Question",
"name": "Les suppléments peuvent-ils aider CD1d ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments, comme les oméga-3, peuvent moduler la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il CD1d ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut altérer la fonction de CD1d et la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent CD1d ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies immunomodulatrices et des anticorps monoclonaux peuvent cibler CD1d."
}
},
{
"@type": "Question",
"name": "CD1d peut-il être une cible pour l'immunothérapie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d est une cible prometteuse pour l'immunothérapie dans certains cancers."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour CD1d ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme l'alpha-galactosylceramide sont en cours d'étude."
}
},
{
"@type": "Question",
"name": "Comment les traitements affectent-ils CD1d ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent moduler l'expression de CD1d et améliorer la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Les thérapies géniques peuvent-elles cibler CD1d ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des approches de thérapie génique sont explorées pour corriger les dysfonctionnements de CD1d."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec CD1d ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections graves et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "CD1d est-il lié à des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une dysfonction de CD1d est associée à un risque accru de certains cancers."
}
},
{
"@type": "Question",
"name": "Les troubles métaboliques sont-ils liés à CD1d ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études montrent un lien potentiel entre CD1d et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de rejet d'organe liés à CD1d ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une altération de CD1d peut augmenter le risque de rejet dans les greffes."
}
},
{
"@type": "Question",
"name": "CD1d influence-t-il les maladies infectieuses ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CD1d joue un rôle dans la susceptibilité aux infections virales et bactériennes."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de dysfonction de CD1d ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux de maladies auto-immunes et infections."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il CD1d ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut affecter l'expression et la fonction de CD1d."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il CD1d ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sédentaire et une mauvaise alimentation peuvent nuire à CD1d."
}
},
{
"@type": "Question",
"name": "Les infections antérieures influencent-elles CD1d ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent altérer l'expression de CD1d et la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Le stress psychologique impacte-t-il CD1d ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress psychologique chronique peut affecter la fonction de CD1d."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 01/04/2025
Contenu vérifié selon les dernières recommandations médicales
6 publications dans cette catégorie
Affiliations :
Division of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA, USA.
5 publications dans cette catégorie
Affiliations :
Division of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA, USA.
Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Publications dans "Antigène CD1d" :
5 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia; cdos@unimelb.edu.au bmoody@bwh.harvard.edu sjwill@unimelb.edu.au dan.pellicci@mcri.edu.au godfrey@unimelb.edu.au.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Publications dans "Antigène CD1d" :
5 publications dans cette catégorie
Affiliations :
Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.
Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia; cdos@unimelb.edu.au bmoody@bwh.harvard.edu sjwill@unimelb.edu.au dan.pellicci@mcri.edu.au godfrey@unimelb.edu.au.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Murdoch Children's Research Institute, Parkville, VIC 3052, Australia.
Department of Paediatrics, The University of Melbourne, Parkville, VIC 3052, Australia.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, The Netherlands jj.vandervliet@amsterdamumc.nl.
LAVA Therapeutics, Utrecht, The Netherlands.
Publications dans "Antigène CD1d" :
4 publications dans cette catégorie
Affiliations :
Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Melbourne, VIC 3010, Australia.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Faculty of Science and Technology , Keio University , 3-14-1 Hiyoshi , Yokohama , Kanagawa 223-8522 , Japan.
Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku , Kyoto , Kyoto 606-8501 , Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Publications dans "Antigène CD1d" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan. motohashi@faculty.chiba-u.jp.
Publications dans "Antigène CD1d" :
Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-related death. As a chronic liver disease, many studies have shown that the immune response plays a key rol...
In this study, patients with HBV-HCC (n=26), patients with hepatitis B-related cirrhosis (HBV-LC) (n=31) and healthy volunteers (n=49) were included. The lymphocytes and their subpopulation phenotypes...
Firstly, our results showed that the percentages of total αβ T cells in the peripheral blood of HBV-HCC patients was significantly decreased compared to healthy subjects. Secondly, we found that naïve...
Our study showed that circulating lymphocytes in HBV-HCC patients exhibited features of immune exhaustion, especially in HCC patients with persistent viral replication and in patients with intermediat...
The interaction of viral surface components with cellular receptors and other entry factors determines key features of viral infection such as host range, tropism and virulence. Despite intensive rese...
Hepatitis B, C and D viruses (HBV, HCV, HDV, respectively) specifically infect human hepatocytes and often establish chronic viral infections of the liver, thus escaping antiviral immunity for years. ...
Hepatitis B virus (HBV) is an enveloped, hepatotropic, noncytopathic virus with a partially double-stranded DNA genome. It infects hepatocytes and is associated with progression to liver fibrosis and ...
Hepatitis B surface antigen (HBsAg) seroconversion is sometimes observed in hepatitis B reactivation (rHBV), probably due to immune resetting and differentiation....
To investigate sequential immune differentiation and abrogation of tolerance in patients with rHBV who achieved HBsAg seroconversion....
We included 19 patients with chronic hepatitis B (CHBV; HBV DNA log10...
At 24 weeks, 81% rHBV (n = 67) lost HBV DNA and HBeAg (41%), and 12 (19%) lost HBsAg and made anti-HBs titers >10 IU/ml. rHBV patients had higher Th1/17, T...
Non-seroconverters have increased inhibitory markers on CD4/CD8 T cells. There is a critical play of CD8, Tfh and B cells and subsets in seroclearance, along with checkpoint molecules as a potential t...
The hepatitis E virus (HEV) is estimated to be responsible for 70,000 deaths annually, yet therapy options remain limited. In the pursuit of effective antiviral therapies, targeting viral entry holds ...
Using our established HEV cell culture model and subgenomic HEV replicons, we found that blocking lysosomal cathepsins (CTS) with small molecule inhibitors, impedes HEV infection without affecting rep...
In summary, our study highlights the pivotal role of lysosomal cathepsins, especially CTSL, in the HEV entry process. The profound anti-HEV efficacy of the pan-cathepsin inhibitor, K11777, especially ...
Chronic viral hepatitis is caused by hepatitis B virus, hepatitis C virus or hepatitis D virus (HBV, HCV, and HDV). Despite different replication strategies, all these viruses rely on secretion throug...
Hepatitis B virus (HBV), a leading cause of developing hepatocellular carcinoma affecting more than 290 million people worldwide, is an enveloped DNA virus specifically infecting hepatocytes. Myristoy...
The placenta is a specialized organ that only performs during pregnancy and serves as an immunological barrier in preventing pathogens to reach the fetus. It has been known that toll-like receptors (T...
We performed enzyme-linked immunoadsorbent assay of HBeAg, HBsAg titer, Anti-HBs, and Anti-HBc to 59 HBsAg-positive pregnant women and identified HBV DNA using nested PCR in their cord blood during de...
Intrauterine exposure to the hepatitis B virus occurred in 69.5% of all pregnant women who were HbsAg positive. TLR2 expression was predominantly identified in syncytiotrophoblast and cytotrophoblast ...
TLR2 expression is not associated with intrauterine exposure of hepatitis B virus....
Hepatitis B virus x (HBx) is a multifunctional protein coded by the Hepatitis B virus that is involved in various cellular processes such as proliferation, cell survival/apoptosis, and histone methyla...