Titre : Cellules HepG2

Cellules HepG2 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Feeding and Eating Disorders

Questions fréquentes et termes MeSH associés

Diagnostic 2

#1

Comment identifier les cellules HepG2 en laboratoire ?

Les cellules HepG2 peuvent être identifiées par leur morphologie et leur marqueur spécifique, l'alpha-fœtoprotéine.
Carcinome hépatocellulaire Lignées cellulaires
#2

Quelles techniques sont utilisées pour étudier les HepG2 ?

Les techniques incluent la culture cellulaire, la microscopie et les tests de viabilité cellulaire.
Culture cellulaire Microscopie

Symptômes 2

#1

Les cellules HepG2 présentent-elles des symptômes ?

Les cellules HepG2 ne présentent pas de symptômes, car elles sont des cellules in vitro.
Symptômes Cellules in vitro
#2

Quels marqueurs sont associés aux cellules HepG2 ?

Les cellules HepG2 expriment des marqueurs comme l'alpha-fœtoprotéine et des enzymes hépatiques.
Marqueurs tumoraux Enzymes hépatiques

Prévention 2

#1

Les cellules HepG2 peuvent-elles aider à prévenir des maladies ?

Elles sont utilisées pour étudier les effets préventifs de composés sur les maladies hépatiques.
Prévention des maladies Composés bioactifs
#2

Comment les HepG2 contribuent-elles à la recherche préventive ?

Elles permettent d'analyser les effets de l'alimentation et des toxines sur la santé hépatique.
Recherche préventive Toxines

Traitements 2

#1

Peut-on utiliser HepG2 pour tester des médicaments ?

Oui, les cellules HepG2 sont souvent utilisées pour évaluer la toxicité et l'efficacité des médicaments.
Essais cliniques Toxicité
#2

Comment les HepG2 aident-elles à développer des traitements ?

Elles permettent d'étudier les mécanismes d'action des médicaments sur le foie et d'identifier des cibles thérapeutiques.
Développement de médicaments Mécanismes d'action

Complications 2

#1

Quelles complications peuvent être étudiées avec HepG2 ?

Les complications liées aux maladies hépatiques, comme la cirrhose et le cancer du foie, peuvent être modélisées.
Cirrhose Cancer du foie
#2

Les HepG2 aident-elles à comprendre les complications du foie ?

Oui, elles sont essentielles pour étudier les mécanismes des complications hépatiques.
Mécanismes pathologiques Complications hépatiques

Facteurs de risque 2

#1

Quels facteurs de risque sont étudiés avec HepG2 ?

Les facteurs de risque comme l'alcool, les médicaments et les toxines sont souvent analysés.
Facteurs de risque Toxines
#2

Comment HepG2 aide à identifier des facteurs de risque ?

Elles permettent d'évaluer l'impact de divers agents sur la santé des cellules hépatiques.
Évaluation des risques Agents toxiques
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 06/05/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Wilson de Melo Cruvinel

5 publications dans cette catégorie

Affiliations :
  • School of Medical and Life Sciences, Escola de Ciências Médicas e da Vida, Pontifícia Universidade Católica de Goiás (PUC GOIÁS), Avenida Universitária 1.440, Setor Universitário, Goiânia, GO, 74605-010, Brazil. melocruvinel@gmail.com.

Paulo Luiz Carvalho Francescantonio

5 publications dans cette catégorie

Affiliations :
  • School of Medical and Life Sciences, Escola de Ciências Médicas e da Vida, Pontifícia Universidade Católica de Goiás (PUC GOIÁS), Avenida Universitária 1.440, Setor Universitário, Goiânia, GO, 74605-010, Brazil.

Alessandra Dellavance

4 publications dans cette catégorie

Affiliations :
  • Research and Development Division, Fleury Medicine and Health Laboratories, São Paulo, Brazil.

Luis Eduardo Coelho Andrade

4 publications dans cette catégorie

Affiliations :
  • Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil. luis.andrade@unifesp.br.
  • Immunology Division, Fleury Medicine and Health Laboratories, São Paulo, Brazil. luis.andrade@unifesp.br.

Antônio Carlos Ximenes

3 publications dans cette catégorie

Affiliations :
  • Hospital Geral de Goiânia Alberto Rassi, Goiânia, GO, Brazil.
Publications dans "Cellules HepG2" :

Cristóvão Luis Pitangueira Mangueira

3 publications dans cette catégorie

Affiliations :
  • Departamento de Patologia Clínica e Anatomia Patológica, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Publications dans "Cellules HepG2" :

Eloísa Bonfá

3 publications dans cette catégorie

Affiliations :
  • Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brazil.
Publications dans "Cellules HepG2" :

Fabiano de Almeida Brito

3 publications dans cette catégorie

Affiliations :
  • Department of Clinical Pathology, School of Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
  • Hermes Pardini Group, Vespasiano, MG, Brazil.
Publications dans "Cellules HepG2" :

Sandra Gofinet Pasoto

3 publications dans cette catégorie

Affiliations :
  • Serviço de Reumatologia e Laboratório de Autoimunidade da Divisão de Laboratório Central do Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Publications dans "Cellules HepG2" :

Carlos Alberto von Mühlen

3 publications dans cette catégorie

Affiliations :
  • Sociedade Brasileira de Autoimunidade, Porto Alegre, RS, Brazil.

Tao Chen

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Xiaoju Wang

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Lijun Zhou

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Shiling Feng

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Ming Yuan

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Chunbang Ding

2 publications dans cette catégorie

Affiliations :
  • College of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Publications dans "Cellules HepG2" :

Wei Li

2 publications dans cette catégorie

Affiliations :
  • State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China. Electronic address: liv880213@foxmail.com.
Publications dans "Cellules HepG2" :

Xi Xie

2 publications dans cette catégorie

Affiliations :
  • Hainan Provincial Key Laboratory for Tropical Hydrobiology and Biotechnology, School of Marine Science, Hainan University, Haikou 570228, China. Electronic address: xiexi@hainu.edu.cn.
Publications dans "Cellules HepG2" :

Tiantian Wu

2 publications dans cette catégorie

Affiliations :
  • State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China. Electronic address: 1532892231@qq.com.
Publications dans "Cellules HepG2" :

Lijie Luo

2 publications dans cette catégorie

Affiliations :
  • State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou 570228, China. Electronic address: luolijie4567@163.com.
Publications dans "Cellules HepG2" :

Sources (10000 au total)

Comparing ICD-11 and DSM-5 eating disorder diagnoses with the Munich eating and feeding disorder questionnaire (ED-Quest).

The new ICD-11 eating disorders (ED) guidelines are similar to the DSM-5 criteria. One difference to the DSM-5 is the inclusion of subjective binges in the definition of bulimia nervosa (BN) and binge... Data of 3863 ED inpatients who completed the Munich Eating and Feeding Disorder Questionnaire were analyzed using standardized diagnostic algorithms for DSM-5 and ICD-11.... Agreement of diagnoses was high (Krippendorff's α = .88, 95% CI [.86, .89]) for anorexia nervosa (AN; 98.9%), BN (97.2%) and BED (100%), and lower for other feeding and eating disorders (OFED; 75.2%).... For over 90% of patients, applying either DSM-5 or ICD-11 diagnostic criteria/guidelines resulted in the same full-threshold ED diagnosis. Sub-threshold and feeding disorders exhibited a discrepancy o... For about 98% of inpatients, the ICD-11 and DSM-5 agree on the same specified eating disorder diagnosis. This is important when comparing diagnoses made by different diagnostic systems. Including subj...

Prospective associations between early childhood parental feeding practices and eating disorder symptoms and disordered eating behaviors in adolescence.

Nonresponsive parental feeding practices are associated with poorer appetite self-regulation in children. It is unknown whether this relationship extends beyond childhood to be prospectively associate... Data were from two population-based cohorts with harmonized measures: Generation R (Netherlands; n = 4900) and Gemini (UK; n = 2094). Parents self-reported their pressure to eat, restriction and instr... In Gemini, pressure to eat in early childhood was associated with adolescents engaging in compensatory behaviors. In Generation R, parental restriction was associated with adolescents engaging in comp... Nonresponsive parental feeding practices were associated with a greater frequency of specific ED symptoms and disordered eating in adolescence, although effect sizes were small and findings were incon... Prospective research examining how early childhood parental feeding practices might contribute to adolescent ED symptoms is limited. In two population-based cohorts, nonresponsive feeding practices (r...

Efficacy of educational interventions in adolescent population with feeding and eating disorders: a systematic review.

Educational interventions are a key element in the care of young patients with feeding and eating disorders, forming part of the majority of therapeutic approaches. The aim of this review is to evalua... Following the PRISMA recommendations electronic databases were searched up to 29 June 2023. Studies related to educational interventions in young population diagnosed with feeding and eating disorders... A total of 191 articles were selected from the 9744 citations screened. Ten publications were included. The results indicated variability between educational programs, including individual and group i... The results indicate that educational interventions can influence the improvement of knowledge level and have a positive effect on health outcomes. Although education is a common practice in the treat... Level I: Systematic review....

Impact of COVID-19 Pandemic on Young Children With Feeding and Eating Problems and Disorders and Their Families.

The incidence of feeding and eating problems and disorders (FEPD) in children increased during the coronavirus disease 2019 (COVID-19) pandemic. The aim of this study was to assess the impact of the C... Cross-sectional survey: parents of children with FEPD (0-11 years) in the Netherlands completed an online questionnaire (January-April 2021). This questionnaire included 4 demographic questions (inclu... In total, 240 children (median age, 5.5 years; interquartile range [IQR], 3.5-7.9 years; 53.3% female) were included; 129 children with FEPD and 111 HC. Most children with FEPD fulfilled criteria for ... It seems that the COVID-19 pandemic had great impact on young children with FEPD and their parents because parents of children with FEPD reported significantly more perceived stress within both the ch...

Parenting styles, maladaptive coping styles, and disturbed eating attitudes and behaviors: a multiple mediation analysis in patients with feeding and eating disorders.

Although preliminary studies support the roles of unhealthy parenting styles and maladaptive coping styles in increasing rates of disturbed eating attitudes and behaviors (EAB) and clinically signific... A total of 102 patients with FED in Zahedan, Iran, participating in this cross-sectional study (from April to March 2022) completed a sociodemographic information form and self-report measures of pare... The results showed that authoritarian parenting style, overcompensation and avoidance coping styles, and female gender might be related to disturbed EAB. The overall hypothesis that overcompensation a... Our findings highlighted the necessity of evaluating particular unhealthy parenting styles and maladaptive coping styles as the important possible risk factors in the development and maintenance of hi...

Core eating disorder fears: Prevalence and differences in eating disorder fears across eating disorder diagnoses.

Fear and anxiety are key maintaining factors for eating disorder (ED) pathology. Maladaptive fears lead to ED behaviors and avoidance, which provide temporary relief, but ultimately reinforce the fear... The current study (N = 229 individuals with an ED) aimed to better characterize ED fears. Specifically, this study examined which ED fears were most endorsed across and within ED diagnoses, and if the... Overall, fear of gaining weight was the most frequently endorsed fear, followed by fear of food, and fear of judgment. Individuals with anorexia nervosa (AN) most frequently endorsed fear of food, ind... These findings suggest ED fears are heterogenous. Given such high heterogeneity, this work highlights the importance of assessing for specific ED fears at the beginning of treatment, which could be us... Eating disorders (EDs) are serious mental illnesses with high rates of medical and psychiatric comorbidities. Fear plays an important role in the development and maintenance of EDs. The present study ...

Eating disorders and disordered eating in servicemen and women: A narrative review.

Eating disorders (EDs) are mental illnesses impacting all aspects of an individual's life. Recent research has examined EDs and disordered-eating behaviors in the military, a population subject to bod... PubMed and PsycINFO were reviewed for relevant articles. All studies including data on EDs or disordered eating in U.S. active-duty, ROTC, or veteran populations were considered.... Results revealed a high burden of EDs and disordered eating with bulimic- and binge-type behaviors being the most common. Servicemembers exposed to trauma, including military sexual assault, and those... The high prevalence of EDs and disordered eating in the military points toward the importance of identification, treatment, and prevention. Policy change is necessary to protect servicemembers....