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Acides aminés, peptides et protéines
Protéines
Protéines de tissu nerveux
Canaux sodiques voltage-dépendants
Canaux sodiques voltage-dépendants : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Canaux sodiques
Électrophysiologie
Électromyographie
Conduction nerveuse
Tests génétiques
Mutations
Douleurs musculaires
Troubles neurologiques
Antécédents médicaux
Syndromes
Symptômes
5
Convulsions
Faiblesse musculaire
Troubles de la marche
Coordination
Douleurs neuropathiques
Picotements
Spasmes musculaires
Hyperexcitabilité
Troubles cognitifs
Signalisation neuronale
Prévention
5
Prévention
Conditions génétiques
Déclencheurs de crises
Stress
Examens réguliers
Anomalies fonctionnelles
Éducation des patients
Gestion des symptômes
Traitements
5
Médicaments antiépileptiques
Stabilisateurs de membrane
Thérapie physique
Force musculaire
Interventions chirurgicales
Cas réfractaires
Mode de vie
Alimentation équilibrée
Traitements personnalisés
Antécédents du patient
Complications
5
Complications
Troubles de la mobilité
Troubles cardiaques
Rythme cardiaque
Complications neurologiques
Déficits moteurs
Gestion des complications
Suivi médical
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Infections virales
Crises
Stress
Exacerbation des symptômes
Médicaments
Fonction des canaux sodiques
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction des canaux sodiques ?",
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"text": "Des tests électrophysiologiques et des études génétiques peuvent être utilisés."
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"text": "L'EMG et les tests de conduction nerveuse sont souvent recommandés."
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"text": "Oui, des dysfonctionnements peuvent entraîner des troubles de la coordination."
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"name": "Comment les douleurs neuropathiques se manifestent-elles ?",
"position": 8,
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"text": "Elles se présentent souvent sous forme de brûlures ou de picotements."
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"text": "Oui, ils peuvent survenir en raison d'une hyperexcitabilité des neurones."
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"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent prévenir des infections qui aggravent les symptômes."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les troubles des canaux sodiques ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les médicaments antiépileptiques et les stabilisateurs de membrane sont courants."
}
},
{
"@type": "Question",
"name": "La thérapie physique est-elle bénéfique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut aider à améliorer la force musculaire et la coordination."
}
},
{
"@type": "Question",
"name": "Les interventions chirurgicales sont-elles nécessaires ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Rarement, mais elles peuvent être envisagées dans des cas graves ou réfractaires."
}
},
{
"@type": "Question",
"name": "Les changements de mode de vie peuvent-ils aider ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation équilibrée et l'exercice régulier peuvent améliorer les symptômes."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils sont souvent adaptés en fonction des symptômes et des antécédents du patient."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec ces troubles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des crises fréquentes et des troubles de la mobilité."
}
},
{
"@type": "Question",
"name": "Les troubles cardiaques sont-ils possibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans les canaux sodiques peuvent affecter le rythme cardiaque."
}
},
{
"@type": "Question",
"name": "Les complications neurologiques sont-elles fréquentes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent inclure des troubles cognitifs et des déficits moteurs."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent réduire l'autonomie et augmenter le besoin de soins médicaux."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être gérées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi médical régulier et des traitements adaptés peuvent aider."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les troubles des canaux sodiques ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, certaines maladies génétiques et des traumatismes peuvent être des facteurs."
}
},
{
"@type": "Question",
"name": "L'âge joue-t-il un rôle dans ces troubles ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains troubles se manifestent plus fréquemment chez les jeunes enfants ou les adultes."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles augmenter le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent déclencher des crises chez les individus prédisposés."
}
},
{
"@type": "Question",
"name": "Le stress est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut exacerber les symptômes chez les personnes déjà affectées."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils influencer le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent interférer avec la fonction des canaux sodiques."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 19/02/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Department of Pharmacology, University of Washington, Seattle, WA 98195, USA. Electronic address: wcatt@uw.edu.
Publications dans "Canaux sodiques voltage-dépendants" :
4 publications dans cette catégorie
Affiliations :
Department of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Publications dans "Canaux sodiques voltage-dépendants" :
4 publications dans cette catégorie
Affiliations :
Department of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Publications dans "Canaux sodiques voltage-dépendants" :
4 publications dans cette catégorie
Affiliations :
Department of Pharmacology, University of Washington, Seattle, WA, United States.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Hopkins Building, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK.
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Hopkins Building, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK. apj10@cam.ac.uk.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Departamento de Neuropatología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
University of Chinese Academy of Sciences, Beijing, China.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
Key Laboratory of Molecular Biophysics of MOE, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
University of Chinese Academy of Sciences, Beijing, China.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Publications dans "Canaux sodiques voltage-dépendants" :
3 publications dans cette catégorie
Affiliations :
Department of Chemistry , Stanford University , Stanford , California 94305 , United States.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Hopkins Building, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK. hl546@cam.ac.uk.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Pathophysiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia; Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Pathophysiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia; Department of Molecular Pharmacology & Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Surgery, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Publications dans "Canaux sodiques voltage-dépendants" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, University of Washington, Seattle, WA, United States.
Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, WA, United States.
Publications dans "Canaux sodiques voltage-dépendants" :
Successful personalized oncology today depends on clinicians taking advantage of the extensive, evidence-based information provided by the National Comprehensive Cancer Network (NCCN) Guidelines, whic...
Previous studies have shown low adherence to surgical staging guidelines in patients with clinical early-stage ovarian carcinoma. The aim of this study was to identify guideline adherence for surgical...
Patients with ovarian cancer and surgical staging registered in the Dutch Gynecological Oncology Audit between January 1, 2015 and December 31, 2019 in the Netherlands were included. Complete surgical...
604 patients underwent surgical staging, 365 (60%) underwent an incomplete staging procedure, 295 (81%) were registered with early-stage disease (International Federation of Gynecology and Obstetrics ...
Guideline adherence for staging was lower than expected and validation of data gave additional insights into the reasons that were contributing to incomplete surgical staging. Moreover, this analysis ...
Patients with a history of chronic obstructive pulmonary disease (COPD) or asthma undergoing surgery are at risk for developing postoperative pulmonary complications, associated with morbidity and mor...
Patients with a history of asthma and/or COPD who underwent non-thoracic surgery between January 2017 and July 2018 in our hospital, were included. Primary outcome was perioperative administration of ...
1,623 patients qualified for a preventative treatment. Overall, 653 patients (40%) received treatment according to protocol. The other 970 patients received no treatment (79%), another corticosteroid ...
The current guideline for prevention of postoperative pulmonary complications has not been implemented thoroughly at our hospital. The lack of adherence appears to be caused by lack in clarity in clin...
Little is known about nationwide practice patterns for the management medullary thyroid cancer (MTC) in relation to the 2015 American Thyroid Association guidelines and their impact on survival....
Using the Surveillance, Epidemiology, and End Results Program database (2000-2018), MTC treatment patterns were evaluated in terms of adherence to the 2015 American Thyroid Association guidelines acro...
A total of 3332 patients with MTC were identified. Of which, 53.8%, 33.2%, and 11.4% of patients had localized, regional, and distant disease, respectively. In patients with locoregional disease, the ...
The rate of guideline-concordant surgery for locoregional MTC increased after guideline publication in 2015, with an observed prolongment in OS and DSS. Chemotherapy use among patients with distant di...
Workplace cancer screening programs are determined as part of an employee's benefits package and health checkups are perceived positively. However, the current status of workplace cancer screening pro...
A cross-sectional study design was employed. Data were obtained from a survey conducted by the "Corporate Action to Promote Cancer Control" between November and December 2022 among registered partner ...
The guideline-adherence rates for colorectal, breast, and cervical cancer screenings in the workplace were 12.7%, 3.0%, and 8.8%, respectively. Enterprises had lower adherence to screening guidelines ...
Adherence to national guidelines for colorectal, breast, and cervical cancer screenings in the workplace was suboptimal among Japanese enterprises. Therefore, appropriate cancer screening measures and...
Despite the availability of evidence-based inflammatory bowel disease (IBD) guidelines, suboptimal care persists. There is little published research assessing barriers to IBD guideline adherence....
To identify barriers to IBD guideline adherence including gastroenterologists' knowledge and attitudes towards guidelines....
An online cross-sectional survey of 824 Australian gastroenterologists was conducted from April to August 2018, with 198 (24%) responses. A novel survey was developed that was informed by the theoreti...
Confidence in guideline recommendations was high; however, referral to them was low. The European Crohn's and Colitis Organisation guidelines were referred to most commonly (43.6%). In multivariate an...
Although gastroenterologists have high confidence in guidelines, they use them infrequently, primarily due to specifics being difficult to remember and lack of time. Self-reported confidence in an are...
Thromboembolic events are a common risk in adults with atrial fibrillation, those with previous cerebrovascular accidents and undergoing emergency or elective surgeries. The widespread availability of...
To improve the management of cancer related pain, the National Comprehensive Cancer Network (NCCN) publishes the Adult Cancer Pain guideline on an annual basis. However, a large majority of oncology p...
The spleen is responsible for blood filtration and mounting an immune response against pathogens. In some people the spleen must be surgically removed because of traumatic events or oncological and he...
Traumatic brain injury (TBI) is a leading cause of death and morbidity worldwide. Evidence-based guidelines for managing severe TBI have been available for over 25 years. However, adherence to guideli...
A structured literature search was conducted using the MEDLINE...
Nine cohort studies were identified that fulfilled the inclusion criteria and answered the clinical question. A review of these papers was conducted....
Mortality after severe TBI improves with increasing adherence to evidence-based guidelines in both adults and children. The evidence also suggests that compliance with guideline recommendations result...