Les maladies neurologiques augmentent-elles le risque ?
Oui, les patients ayant des maladies neurologiques peuvent être plus sensibles aux effets des bloqueurs.
Maladies neurologiquesSensibilitéRisque
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Bloqueurs de canaux sodiques voltage-dépendants : Questions médicales les plus fréquentes",
"headline": "Bloqueurs de canaux sodiques voltage-dépendants : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Bloqueurs de canaux sodiques voltage-dépendants : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-07-25",
"dateModified": "2025-04-21",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Bloqueurs de canaux sodiques voltage-dépendants"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Bloqueurs de canaux sodiques",
"url": "https://questionsmedicales.fr/mesh/D026941",
"about": {
"@type": "MedicalCondition",
"name": "Bloqueurs de canaux sodiques",
"code": {
"@type": "MedicalCode",
"code": "D026941",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "D27.505.954.411.720"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Bloqueurs de canaux sodiques voltage-dépendants",
"alternateName": "Voltage-Gated Sodium Channel Blockers",
"code": {
"@type": "MedicalCode",
"code": "D061567",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "William A Catterall",
"url": "https://questionsmedicales.fr/author/William%20A%20Catterall",
"affiliation": {
"@type": "Organization",
"name": "Department of Pharmacology, University of Washington, Seattle, WA 98195, USA. Electronic address: wcatt@uw.edu."
}
},
{
"@type": "Person",
"name": "Piyasuda Pukkanasut",
"url": "https://questionsmedicales.fr/author/Piyasuda%20Pukkanasut",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA."
}
},
{
"@type": "Person",
"name": "Sadanandan E Velu",
"url": "https://questionsmedicales.fr/author/Sadanandan%20E%20Velu",
"affiliation": {
"@type": "Organization",
"name": "Department of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA."
}
},
{
"@type": "Person",
"name": "Tamer M Gamal El-Din",
"url": "https://questionsmedicales.fr/author/Tamer%20M%20Gamal%20El-Din",
"affiliation": {
"@type": "Organization",
"name": "Department of Pharmacology, University of Washington, Seattle, WA, United States."
}
},
{
"@type": "Person",
"name": "Christopher L-H Huang",
"url": "https://questionsmedicales.fr/author/Christopher%20L-H%20Huang",
"affiliation": {
"@type": "Organization",
"name": "Department of Biochemistry, Hopkins Building, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Nerve entry points - The anatomy beneath trigger points.",
"datePublished": "2023-05-03",
"url": "https://questionsmedicales.fr/article/37330756",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jbmt.2023.04.083"
}
},
{
"@type": "ScholarlyArticle",
"name": "Device for Dual Ultrasound and Dry Needling Trigger Points Treatment.",
"datePublished": "2023-01-04",
"url": "https://questionsmedicales.fr/article/36679375",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3390/s23020580"
}
},
{
"@type": "ScholarlyArticle",
"name": "Association between myofascial trigger point therapy and conditioned pain modulation.",
"datePublished": "2023-12-28",
"url": "https://questionsmedicales.fr/article/38763618",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jbmt.2023.12.005"
}
},
{
"@type": "ScholarlyArticle",
"name": "Abdominal Wall Pain and Primary Dysmenorrhea: The Importance of Myofascial Trigger Points.",
"datePublished": "2023-03-14",
"url": "https://questionsmedicales.fr/article/36893743",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1159/000530035"
}
},
{
"@type": "ScholarlyArticle",
"name": "Hair Follicle Melanocytes Initiate Autoimmunity in Alopecia Areata: a Trigger Point.",
"datePublished": "2022-09-19",
"url": "https://questionsmedicales.fr/article/36121544",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1007/s12016-022-08954-w"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Actions chimiques et utilisations",
"item": "https://questionsmedicales.fr/mesh/D020164"
},
{
"@type": "ListItem",
"position": 3,
"name": "Actions pharmacologiques",
"item": "https://questionsmedicales.fr/mesh/D020228"
},
{
"@type": "ListItem",
"position": 4,
"name": "Utilisations thérapeutiques",
"item": "https://questionsmedicales.fr/mesh/D045506"
},
{
"@type": "ListItem",
"position": 5,
"name": "Agents cardiovasculaires",
"item": "https://questionsmedicales.fr/mesh/D002317"
},
{
"@type": "ListItem",
"position": 6,
"name": "Bloqueurs de canaux sodiques",
"item": "https://questionsmedicales.fr/mesh/D026941"
},
{
"@type": "ListItem",
"position": 7,
"name": "Bloqueurs de canaux sodiques voltage-dépendants",
"item": "https://questionsmedicales.fr/mesh/D061567"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Bloqueurs de canaux sodiques voltage-dépendants - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-12",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Comment diagnostiquer une intoxication aux bloqueurs de canaux sodiques ?\nQuels tests sont utilisés pour évaluer l'effet des bloqueurs ?\nQuels symptômes indiquent une surdose de bloqueurs ?\nComment différencier les types de bloqueurs de canaux ?\nQuels antécédents médicaux sont pertinents pour le diagnostic ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Quels sont les symptômes d'une intoxication aiguë ?\nComment se manifestent les effets secondaires des bloqueurs ?\nQuels signes indiquent une réaction allergique ?\nLes bloqueurs affectent-ils la respiration ?\nQuels symptômes neurologiques peuvent apparaître ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Comment prévenir les effets indésirables des bloqueurs ?\nQuelles précautions doivent être prises avant la prescription ?\nLes patients doivent-ils être informés des risques ?\nComment éviter les interactions médicamenteuses ?\nQuelles sont les recommandations pour les patients à risque ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Quel est le traitement d'une surdose de bloqueurs ?\nComment gérer les effets secondaires des bloqueurs ?\nQuels médicaments peuvent interagir avec les bloqueurs ?\nLes bloqueurs sont-ils utilisés en anesthésie ?\nQuelle est l'importance de la surveillance pendant le traitement ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Quelles complications peuvent survenir avec les bloqueurs ?\nComment les complications sont-elles gérées ?\nLes complications sont-elles fréquentes ?\nQuels facteurs augmentent le risque de complications ?\nLes complications peuvent-elles être évitées ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Bloqueurs de canaux sodiques voltage-dépendants",
"description": "Quels sont les principaux facteurs de risque ?\nComment l'âge influence-t-il le risque ?\nLes antécédents familiaux jouent-ils un rôle ?\nL'usage de drogues illicites est-il un facteur de risque ?\nLes maladies neurologiques augmentent-elles le risque ?",
"url": "https://questionsmedicales.fr/mesh/D061567?mesh_terms=Trigger+Points#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une intoxication aux bloqueurs de canaux sodiques ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un diagnostic repose sur l'historique médical, les symptômes cliniques et des tests sanguins."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'effet des bloqueurs ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des électrocardiogrammes et des tests de conduction nerveuse peuvent être utilisés."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une surdose de bloqueurs ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des convulsions, une arythmie cardiaque et une dépression respiratoire peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment différencier les types de bloqueurs de canaux ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'analyse des effets cliniques et des mécanismes d'action aide à les différencier."
}
},
{
"@type": "Question",
"name": "Quels antécédents médicaux sont pertinents pour le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents de maladies cardiaques ou neurologiques sont cruciaux pour le diagnostic."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une intoxication aiguë ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des vertiges, des nausées, des troubles de la vision et des convulsions."
}
},
{
"@type": "Question",
"name": "Comment se manifestent les effets secondaires des bloqueurs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent provoquer des étourdissements, des maux de tête et des troubles de la coordination."
}
},
{
"@type": "Question",
"name": "Quels signes indiquent une réaction allergique ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des éruptions cutanées, des démangeaisons et un gonflement peuvent signaler une allergie."
}
},
{
"@type": "Question",
"name": "Les bloqueurs affectent-ils la respiration ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent entraîner une dépression respiratoire dans les cas graves."
}
},
{
"@type": "Question",
"name": "Quels symptômes neurologiques peuvent apparaître ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des convulsions, des troubles de la conscience et des paralysies peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment prévenir les effets indésirables des bloqueurs ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une prescription appropriée et une éducation du patient sont essentielles pour prévenir les effets indésirables."
}
},
{
"@type": "Question",
"name": "Quelles précautions doivent être prises avant la prescription ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évaluer les antécédents médicaux et les allergies du patient est crucial avant la prescription."
}
},
{
"@type": "Question",
"name": "Les patients doivent-ils être informés des risques ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, informer les patients des risques et des signes d'intoxication est essentiel."
}
},
{
"@type": "Question",
"name": "Comment éviter les interactions médicamenteuses ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un examen minutieux des médicaments prescrits et des antécédents est nécessaire pour éviter les interactions."
}
},
{
"@type": "Question",
"name": "Quelles sont les recommandations pour les patients à risque ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les patients à risque doivent être suivis de près et éduqués sur les signes d'alerte."
}
},
{
"@type": "Question",
"name": "Quel est le traitement d'une surdose de bloqueurs ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement inclut des soins de soutien, l'administration de charbon actif et des antidotes si disponibles."
}
},
{
"@type": "Question",
"name": "Comment gérer les effets secondaires des bloqueurs ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion implique l'ajustement de la dose ou le changement de médicament selon les symptômes."
}
},
{
"@type": "Question",
"name": "Quels médicaments peuvent interagir avec les bloqueurs ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme les antidépresseurs et les anesthésiques peuvent interagir."
}
},
{
"@type": "Question",
"name": "Les bloqueurs sont-ils utilisés en anesthésie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains bloqueurs de canaux sodiques sont utilisés pour induire une anesthésie locale."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance de la surveillance pendant le traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "La surveillance est cruciale pour détecter les effets indésirables et ajuster le traitement."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les bloqueurs ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des arythmies, des convulsions et des défaillances respiratoires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Comment les complications sont-elles gérées ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une intervention rapide et un traitement symptomatique."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications sont rares mais peuvent survenir, surtout en cas de surdose ou d'interactions."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de complications ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs comme l'âge avancé, les maladies cardiaques et l'utilisation concomitante d'autres médicaments augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les complications peuvent-elles être évitées ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surveillance attentive et une éducation adéquate peuvent aider à prévenir certaines complications."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents de maladies cardiaques, l'âge et l'utilisation d'autres médicaments sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Comment l'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes âgées ont un risque accru de complications en raison de la polypharmacie et de la fragilité."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies cardiaques ou neurologiques peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "L'usage de drogues illicites est-il un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'usage de certaines drogues peut interagir avec les bloqueurs et augmenter le risque d'effets indésirables."
}
},
{
"@type": "Question",
"name": "Les maladies neurologiques augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients ayant des maladies neurologiques peuvent être plus sensibles aux effets des bloqueurs."
}
}
]
}
]
}
Myofascial trigger points (MTrPs) have been the subject of considerable scientific research for almost forty years. In their seminal paper, Travell and Simons described a model based on the presence o...
Literature search of digital databases....
A total of 4631 abstracts were screened; 72 were selected for further review. Four articles made a direct connection between MTrPs and NEPs. Another fifteen articles provided high-quality data regardi...
There is sufficient evidence to hypothesise that NEPs are the anatomical basis for MTrPs. This presented hypothesis addresses one of the crucial issues in diagnosing trigger points, which is the lack ...
Ultrasound is a well-known tool to produce thermal and non-thermal effects on cells and tissues. These effects require an appropriate application of ultrasound in terms of localization and acoustic en...
Myofascial trigger point therapy (MTrP) is a widely used therapeutic approach, although the underlying mechanisms remain unclear. Mechanisms discussed include peripheral involvement of muscles as well...
Both, CPM and MTrP protocols consisted of heat-based test stimuli (heat pain thresholds before and after the intervention) and pressure-based (conditioning) stimuli. Asymptomatic participants (n = 94)...
A significant correlation was shown between the analgesic effect of CPM and MTrP therapy for mild (r = 0.53, p = 0.002) and intensive stimuli (r = 0.73, p < 0.001). 17.3% of the variance of the MTrP e...
Between the analgesic responses following MTrP and CPM paradigms, a moderate to strong correlation was observed, suggesting shared underlying mechanisms....
Myofascial trigger points are among the often-overlooked causes of anterior abdominal wall pain and primer dysmenorrhea. It is crucial to evaluate patients with a myofascial perspective in addition to...
Alopecia areata (AA) is characterized by common non-scarring alopecia due to autoimmune disorders. To date, the specific pathogenesis underlying AA remains unknown. Thus, AA treatment in the dermatolo...
Myofascial pain syndrome is a painful local or regional disease caused by myofascial trigger points. Trigger point injection (TPI) is a frequently used method for the treatment of myofascial pain. Maj...
A 24-year-old woman, without medical history of any disease, was diagnosed with myofascial syndrome based on the presence of long-standing neck and right arm pain, and TPI with lidocaine was applied t...
The reported patient is the first in the literature who suffered from ischemic stroke after TPI. The use of ultrasound for injections into the neck muscles could avoid serious complications....
Ultrasonographic evaluation of trigger points detected by physical examination in patients with myofascial pain syndrome is being used more frequently in clinical care. However, the sonographic appear...
To reveal the presence of trigger points with ultrasonography in those with myofascial pain syndrome and to determine if ultrasound images can help discriminate between demographic and disease charact...
Fifty-two participants with chronic neck pain (NP) were in this cross-sectional study. The pain intensity was evaluated using a 0-10 cm visual analog scale (VAS). The neck disability index measured th...
There was a positive correlation between the VAS scores of the participants and the ultrasonographic detection of myofascial trigger points (MTPs) in the multifidus and middle trapezius muscles (right...
The detection of MTPs with ultrasonography is associated with the severity of pain and disability in those with chronic NP. Features on ultrasound include hypoechoic changes within muscle and reduced ...
To observe the effect of the acupuncture of myofascial trigger points (MTrPs) in the treatment of lower extremity varicose veins (LEVVs)....
Overall, 260 patients with LEVVs participated in this study. LEVVs were selected based on diagnostic criteria of Clinical, Etiology, Anatomy, and Pathophysiology levels 2-5 and classified into six typ...
The mean evaluation score of LEVVs before the treatment course was 3.66 ± 1.19. After the course, this reduced to 1.18 ± 0.97, with the following response rates: 85% for excellent and good and 15% for...
In some patients, MTrP acupuncture could cure LEVVs and its accompanying symptoms. These LEVVs are probably caused by fascia tension as a pre-pathology induced by the MTrPs....
The etiology of plantar heel pain is multifactorial. Myofascial trigger points of abductor hallucis muscle one of the muscles that should be carefully evaluated and treated in patients diagnosed with ...
Temporomandibular disorder (TMD) is an umbrella term encompassing various clinical complaints involving the temporomandibular joints, masticatory muscles, and/or associated orofacial structures. Myoge...
To investigate muscle oxygenation and pain immediately after DN application on an MTP in the masseter muscle of patients with myogenous TMDs....
Masseter muscle oxygen tissue saturation indices (TSI%) were assessed by near-infrared spectroscopy (NIRS) pre- and post-interventions by a randomized, controlled, double-blind, crossover DN/Sham clin...
We found a significant difference (2,108% vs. 0,142%) between masseter muscle TSI% deltas after the DN and Sham interventions, respectively (n=24). We only evaluated women since men refused to follow ...
These findings show an increase in tissue oxygen saturation in the evaluated sample immediately after the DN intervention on the MTP of patients' masseter muscle. Pain may have increased immediately a...
