Laboratory of Growth Regulators, Institute of Experimental Botany of the Czech Academy of Sciences & Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, University of Chemistry and Technology in Prague, Technická 5, Prague, Czech Republic.
Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Protein Biochemistry and Proteomics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Protein Biochemistry and Proteomics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Molecular Biology, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Chemical Biology and Genetics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelů 27, Olomouc, Czech Republic.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Otolaryngology, Head and Neck Surgery, and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Otolaryngology, Head and Neck Surgery, and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Otolaryngology, Guangdong Women and Children Hospital, Guangzhou, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Otolaryngology, Head and Neck Surgery, and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Otolaryngology, Head and Neck Surgery, and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Department of Otolaryngology, Head and Neck Surgery, and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China.
University of Chinese Academy of Sciences, CAS, Beijing, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China.
University of Chinese Academy of Sciences, CAS, Beijing, China.
School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China.
University of Chinese Academy of Sciences, CAS, Beijing, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China.
University of Chinese Academy of Sciences, CAS, Beijing, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai, China.
University of Chinese Academy of Sciences, CAS, Beijing, China.
School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing, China.
Publications dans "Inhibiteurs de l'acétaldéhyde déshydrogénase" :
Cholangiocarcinoma (CCA) is the most recurrent malignant tumor found in the biliary system. It originates from the bile duct epithelial cells characterized by easy metastasis, high intermittent rate, ...
Aldehyde dehydrogenase (ALDH) is widely distributed in nature and its characteristics have been examined. ALDH plays an important role in aldehyde detoxification. Sources of aldehydes include incomple...
Acetaldehyde dehydrogenase 2 (ALDH2) is the second enzyme involved in the breakdown of acetaldehyde into acetic acid during the process of alcohol metabolism. Roughly 40% of East Asians carry one or t...
Lactate dehydrogenase (LDH) is a crucial enzyme involved in energy metabolism and present in various cells throughout the body. Its diverse physiological functions encompass glycolysis, and its abnorm...
Protective effect of quercetin against acetaldehyde was evaluated using the cultured hepatocyte models with aldehyde dehydrogenase (ALDH) isozyme deficiency (aldh2-kd and aldh1a1-kd). The quercetin-in...
Asymmetric organocatalyzed multicomponent reactions represent an important toolbox in the field of organic synthesis to build complex scaffolds starting from simple starting materials. The Enders thre...
Lactate dehydrogenase (LDH) is a key enzyme in glycolysis responsible for the conversion of pyruvate into lactate and vice versa. Lactate plays a crucial role in tumor progression and metastasis; ther...
This review covers patents published since 2014 up to the present in the Espacenet database, concerning LDH inhibitors and their potential therapeutic applications....
Over the past ten years, different compounds have been identified as LDH inhibitors. Some of them are derived from the chemical optimization of already known LDH inhibitors (e.g. pyrazolyl derivatives...
Isocitrate dehydrogenase (IDH) mutant gliomas are a primary malignancy of the central nervous system (CNS) malignancies, most commonly affecting adults under the age of 55. Standard of care therapy fo...