questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Cytochromes
Cytochrome P-450 enzyme system
Famille-2 de cytochromes P450
Limonène hydroxylases
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2C9 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Tests génétiques
Polymorphisme génétique
Effets indésirables
Réponse au traitement
Interactions médicamenteuses
Profil métabolique
Métabolisme hépatique
Analyses sanguines
Symptômes
5
Nausées
Réactions allergiques
Surdose
Douleurs abdominales
Effets secondaires
Efficacité des médicaments
Carence enzymatique
Effets indésirables
Toxicité médicamenteuse
Éruptions cutanées
Prévention
5
Prévention
Suivi régulier
Anticoagulants
Saignement
Interactions médicamenteuses
Information médicale
Tests préventifs
Complications
Sensibilisation
Tests génétiques
Traitements
5
Ajustement de dose
Tests génétiques
Gestion des interactions
Surveillance thérapeutique
Traitements alternatifs
Médicaments
Surdose
Soins symptomatiques
Complications
5
Complications
Réactions allergiques
Surdose
Dommages organiques
Gestion des complications
Surveillance étroite
Déficience enzymatique
Maladies chroniques
Interactions médicamenteuses
Hospitalisations
Facteurs de risque
5
Facteurs de risque
Génétique
Alimentation
Inhibition enzymatique
Antifongiques
Inhibition enzymatique
Maladies hépatiques
Métabolisme des médicaments
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"name": "Quels signes d'une interaction médicamenteuse ?",
"position": 8,
"acceptedAnswer": {
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}
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"position": 9,
"acceptedAnswer": {
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"name": "Quels symptômes d'une toxicité médicamenteuse ?",
"position": 10,
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}
},
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"name": "Comment prévenir les effets indésirables ?",
"position": 11,
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"name": "Quels conseils pour les patients sous anticoagulants ?",
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}
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"position": 13,
"acceptedAnswer": {
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"name": "Quels tests préventifs pour CYP2C9 ?",
"position": 14,
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"position": 15,
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"name": "Comment ajuster les doses pour CYP2C9 ?",
"position": 16,
"acceptedAnswer": {
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"@type": "Question",
"name": "Quels médicaments sont métabolisés par CYP2C9 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme la warfarine, le phénytoïne et certains AINS sont métabolisés par CYP2C9."
}
},
{
"@type": "Question",
"name": "Comment gérer les interactions médicamenteuses ?",
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"acceptedAnswer": {
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}
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"name": "Quels traitements alternatifs pour les déficients ?",
"position": 19,
"acceptedAnswer": {
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"@type": "Question",
"name": "Comment traiter une surdose liée à CYP2C9 ?",
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"position": 21,
"acceptedAnswer": {
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}
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"@type": "Question",
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"position": 22,
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"position": 23,
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"@type": "Question",
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"position": 24,
"acceptedAnswer": {
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"text": "Une déficience peut entraîner des effets à long terme sur la santé, comme des maladies chroniques."
}
},
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"name": "Quelles complications liées aux interactions ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les interactions peuvent provoquer des complications comme des hospitalisations ou des traitements prolongés."
}
},
{
"@type": "Question",
"name": "Quels facteurs influencent CYP2C9 ?",
"position": 26,
"acceptedAnswer": {
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"text": "Des facteurs comme la génétique, l'âge et l'alimentation influencent l'activité de CYP2C9."
}
},
{
"@type": "Question",
"name": "Comment l'âge affecte CYP2C9 ?",
"position": 27,
"acceptedAnswer": {
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"text": "L'âge avancé peut réduire l'activité de CYP2C9, augmentant le risque d'effets indésirables."
}
},
{
"@type": "Question",
"name": "Quel rôle de l'alimentation sur CYP2C9 ?",
"position": 28,
"acceptedAnswer": {
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"text": "Certaines substances alimentaires peuvent inhiber ou induire l'activité de CYP2C9."
}
},
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"name": "Quels médicaments augmentent le risque ?",
"position": 29,
"acceptedAnswer": {
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"text": "Des médicaments comme les antifongiques peuvent inhiber CYP2C9, augmentant le risque d'effets indésirables."
}
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"@type": "Question",
"name": "Comment les maladies hépatiques affectent CYP2C9 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les maladies hépatiques peuvent réduire l'activité de CYP2C9, affectant le métabolisme des médicaments."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 29/03/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary. Electronic address: poor.miklos@pte.hu.
Publications dans "Cytochrome P-450 CYP2C9" :
In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2021-12-13
Interaction of myricetin, ampelopsin (dihydromyricetin), and their sulfate metabolites with serum albumin, cytochrome P450 (CYP2C9, 2C19, and 3A4) enzymes, and organic anion-transporting polypeptides (OATP1B1 and OATP2B1).
Pharmacology research & perspectives
Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2022-12-05
3 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Federal University of Minas Gerais, Av. Presidente Antonio Carlos, 667, Campus Pampulha, Belo Horizonte-MG, CEP: 31270-901, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Drug Resistance Research Group, Institute of Molecular Life Sciences, Research Centre for Natural Sciences, HUN-REN, Budapest, Hungary.
Doctoral School of Biology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Drug Resistance Research Group, Institute of Molecular Life Sciences, Research Centre for Natural Sciences, HUN-REN, Budapest, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
Individual variability in dispersal and reproduction abilities can lead to evolutionary processes that may have significant effects on the speed and shape of biological invasions. Spatial sorting, an ...
Differential sensitivity analysis is indispensable in fitting parameters, understanding uncertainty, and forecasting the results of both thought and lab experiments. Although there are many methods cu...
In this paper we study an important global regulation mechanism of transcription of biological cells using specific macro-molecules, 6S RNAs. The functional property of 6S RNAs is of blocking the tran...
Nanoconstructs developed for biomedical purposes must overcome diverse biological barriers before reaching the target where playing their therapeutic or diagnostic function. In vivo models are very co...
The Turing model (or reaction-diffusion model), first published in 1952, is a mathematical model that can account for autonomy in the morphogenesis of organisms. Although initially controversial, the ...
Spatial simulations are becoming an increasingly ubiquitous component in the cycle of discovery, experimentation, and communication across the sciences. In cell biology, many researchers share a visio...
The Biology System Description Language (BiSDL) is an accessible, easy-to-use computational language for multicellular synthetic biology. It allows synthetic biologists to represent spatiality and mul...
BiSDL's effectiveness is showcased through three case studies on complex multicellular systems: a bacterial consortium, a synthetic morphogen system and a conjugative plasmid transfer process. These s...
BiSDL represents a significant step forward in computational languages for synthetic biology, providing a sophisticated yet user-friendly tool for designing and simulating complex biological systems w...
Dynamical systems modeling, particularly via systems of ordinary differential equations, has been used to effectively capture the temporal behavior of different biochemical components in signal transd...
Estimating model parameters is a crucial step in mathematical modelling and typically involves minimizing the disagreement between model predictions and experimental data. This calibration data can ch...
Certain emerging pollutants are among the most widely used chemicals globally, causing widespread concern in relation to their use in products devoted to cleaniness and asepsis. Nonylphenol ethoxylate...