Utility of Electronic Medical Record Alerts to Prevent Drug Nephrotoxicity.
Acute Kidney Injury
Alert
Clinical Decision Support
Drug Prescriptions
Electronic Health Records
Humans
Iatrogenic Disease
Inappropriate Prescribing
acute renal failure
drug nephrotoxicity
nephrotoxicity
pharmacokinetics
Journal
Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570
Informations de publication
Date de publication:
07 01 2019
07 01 2019
Historique:
pubmed:
7
4
2018
medline:
4
3
2020
entrez:
7
4
2018
Statut:
ppublish
Résumé
Nephrotoxin-induced AKI is an iatrogenic form of AKI that can be potentially avoided or ameliorated by prompt recognition and appropriate prescriber actions. Drug-targeted alerts, either for patients at risk of AKI or patients with existing AKI, may lead to more appropriate drug dosing and management and improved clinical outcomes. However, alerts of this type are complicated to create, have a high potential for error and off-target effects, and may be difficult to evaluate. Although many studies have shown that these alerts can reduce the rate of inappropriate prescribing, few studies have examined the utility of such alerts in terms of patient benefit. In this review, we examine the current state of the literature in this area, identify key technical challenges, and suggest methods of evaluation for drug-targeted AKI alerts.
Identifiants
pubmed: 29622668
pii: 01277230-201901000-00019
doi: 10.2215/CJN.13841217
pmc: PMC6364537
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
115-123Subventions
Organisme : NIDDK NIH HHS
ID : K23 DK097201
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK079310
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK113191
Pays : United States
Informations de copyright
Copyright © 2019 by the American Society of Nephrology.
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