Bilateral Versus Single Internal Mammary Artery Use in Coronary Artery Bypass Grafting: A Propensity Matched Analysis.


Journal

Heart, lung & circulation
ISSN: 1444-2892
Titre abrégé: Heart Lung Circ
Pays: Australia
ID NLM: 100963739

Informations de publication

Date de publication:
May 2019
Historique:
received: 31 12 2017
revised: 18 03 2018
accepted: 23 03 2018
pubmed: 22 8 2018
medline: 13 4 2019
entrez: 22 8 2018
Statut: ppublish

Résumé

Bilateral internal mammary artery (BIMA) grafts have demonstrated superior long-term outcomes compared with single internal mammary artery (SIMA) grafts. Despite this, BIMA remains widely underutilised due to perceived technical challenges and concerns regarding wound healing. We sought to examine the morbidity and mortality associated with BIMA use in a propensity-matched cohort of patients. From 2009 to 2016, 3,594 consecutive patients underwent coronary artery bypass surgery at three affiliated institutions. Thirty-day (30) mortality and morbidity data were collected prospectively. Propensity-score matched analyses were performed for BIMA versus SIMA use controlling for a number of preoperative characteristics. Overall, 29% of procedures were performed off pump, with a greater proportion in the BIMA group (43% vs. 21%, p<0.001). In the propensity-score analysis consisting of 820 matched pairs, there were similar rates of 30-day mortality (1.3% BIMA vs. 0.9% SIMA, p=0.48) and deep sternal wound infection (1.1% BIMA vs. 0.9% SIMA, p=0.84). The rate of superficial sternal wound infection trended towards being higher in the BIMA group (2.6% vs. 1.3%, p=0.077). The rates of red blood cell transfusions (27.4% vs. 27%, p=0.217), other blood product transfusions (18% vs. 20%, p=0.217), and reoperation for bleeding (2.9% vs. 2.1%, p=0.349) were similar. Bilateral internal mammary artery use was associated with similar rates of deep sternal wound infection compared to SIMA use, with a preponderance of superficial sternal wound infections that did not result in increased mortality or transfusion requirements. The use of BIMA should be more widely considered for coronary artery bypass surgery.

Sections du résumé

BACKGROUND BACKGROUND
Bilateral internal mammary artery (BIMA) grafts have demonstrated superior long-term outcomes compared with single internal mammary artery (SIMA) grafts. Despite this, BIMA remains widely underutilised due to perceived technical challenges and concerns regarding wound healing. We sought to examine the morbidity and mortality associated with BIMA use in a propensity-matched cohort of patients.
METHODS METHODS
From 2009 to 2016, 3,594 consecutive patients underwent coronary artery bypass surgery at three affiliated institutions. Thirty-day (30) mortality and morbidity data were collected prospectively. Propensity-score matched analyses were performed for BIMA versus SIMA use controlling for a number of preoperative characteristics.
RESULTS RESULTS
Overall, 29% of procedures were performed off pump, with a greater proportion in the BIMA group (43% vs. 21%, p<0.001). In the propensity-score analysis consisting of 820 matched pairs, there were similar rates of 30-day mortality (1.3% BIMA vs. 0.9% SIMA, p=0.48) and deep sternal wound infection (1.1% BIMA vs. 0.9% SIMA, p=0.84). The rate of superficial sternal wound infection trended towards being higher in the BIMA group (2.6% vs. 1.3%, p=0.077). The rates of red blood cell transfusions (27.4% vs. 27%, p=0.217), other blood product transfusions (18% vs. 20%, p=0.217), and reoperation for bleeding (2.9% vs. 2.1%, p=0.349) were similar.
CONCLUSIONS CONCLUSIONS
Bilateral internal mammary artery use was associated with similar rates of deep sternal wound infection compared to SIMA use, with a preponderance of superficial sternal wound infections that did not result in increased mortality or transfusion requirements. The use of BIMA should be more widely considered for coronary artery bypass surgery.

Identifiants

pubmed: 30126790
pii: S1443-9506(18)30138-0
doi: 10.1016/j.hlc.2018.03.022
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

807-813

Informations de copyright

Crown Copyright © 2018. Published by Elsevier B.V. All rights reserved.

Auteurs

Ying Yan Zhu (YY)

The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia. Electronic address: yingyan.zhu@gmail.com.

Michael Seco (M)

Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Stella R Harris (SR)

Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia.

Michalis Koullouros (M)

Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia.

Fabio Ramponi (F)

The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Michael Wilson (M)

The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Royal Prince Alfred Institute of Academic Surgery, Sydney, NSW, Australia.

Paul G Bannon (PG)

The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Royal Prince Alfred Institute of Academic Surgery, Sydney, NSW, Australia.

Michael P Vallely (MP)

The Baird Institute of Applied Heart & Lung Surgical Research, Sydney, NSW, Australia; Cardiothoracic Surgery Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Australian School of Advanced Medicine, Macquarie University, Sydney, NSW, Australia.

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