Macular edema after cataract surgery in eyes with and without pseudoexfoliation syndrome.
Aged
Aged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal
/ administration & dosage
Dexamethasone
/ administration & dosage
Diclofenac
/ administration & dosage
Double-Blind Method
Exfoliation Syndrome
/ complications
Female
Glaucoma, Open-Angle
/ complications
Glucocorticoids
/ administration & dosage
Humans
Intraocular Pressure
/ physiology
Macular Edema
/ etiology
Male
Middle Aged
Phacoemulsification
/ adverse effects
Postoperative Complications
Prospective Studies
Retina
/ diagnostic imaging
Tomography, Optical Coherence
Visual Acuity
/ physiology
Aqueous flare
cataract
central retinal thickness
macular edema
phacoemulsification
pseudoexfoliation syndrome
Journal
European journal of ophthalmology
ISSN: 1724-6016
Titre abrégé: Eur J Ophthalmol
Pays: United States
ID NLM: 9110772
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
pubmed:
13
9
2018
medline:
23
11
2019
entrez:
13
9
2018
Statut:
ppublish
Résumé
The purpose of the study was to identify macular edema after cataract surgery in eyes with and without pseudoexfoliation syndrome. The study was a post-hoc analysis of a randomized, double-blind, prospective single-center study. Patients were enrolled between January 2016 and October 2016 as per the national guidelines for the management of cataract in the Department of Ophthalmology, Kymenlaakso Central Hospital, Kotka, Finland. One hundred and fifty-six eyes of 149 patients undergoing routine cataract surgery. Postoperatively anti-inflammatory medication was either dexamethasone (N = 78) or diclofenac (N = 78). Spectral domain optical coherence tomography imaging and laser flare meter measurement of the anterior chamber were conducted before surgery and at the control visit 28 days postoperatively. Baseline variables were comparable between eyes with pseudoexfoliation syndrome (N = 32) and those without (N = 124), except for intraocular pressure ( Eyes with pseudoexfoliation syndrome may be predisposed to an increased aqueous flare and macular edema after cataract surgery. This study outlines the need to determine the optimal anti-inflammatory medication after cataract surgery in patients with pseudoexfoliation syndrome.
Sections du résumé
BACKGROUND
BACKGROUND
The purpose of the study was to identify macular edema after cataract surgery in eyes with and without pseudoexfoliation syndrome. The study was a post-hoc analysis of a randomized, double-blind, prospective single-center study. Patients were enrolled between January 2016 and October 2016 as per the national guidelines for the management of cataract in the Department of Ophthalmology, Kymenlaakso Central Hospital, Kotka, Finland.
METHODS
METHODS
One hundred and fifty-six eyes of 149 patients undergoing routine cataract surgery. Postoperatively anti-inflammatory medication was either dexamethasone (N = 78) or diclofenac (N = 78). Spectral domain optical coherence tomography imaging and laser flare meter measurement of the anterior chamber were conducted before surgery and at the control visit 28 days postoperatively.
RESULTS
RESULTS
Baseline variables were comparable between eyes with pseudoexfoliation syndrome (N = 32) and those without (N = 124), except for intraocular pressure (
CONCLUSION
CONCLUSIONS
Eyes with pseudoexfoliation syndrome may be predisposed to an increased aqueous flare and macular edema after cataract surgery. This study outlines the need to determine the optimal anti-inflammatory medication after cataract surgery in patients with pseudoexfoliation syndrome.
Identifiants
pubmed: 30205708
doi: 10.1177/1120672118799622
doi:
Substances chimiques
Anti-Inflammatory Agents, Non-Steroidal
0
Glucocorticoids
0
Diclofenac
144O8QL0L1
Dexamethasone
7S5I7G3JQL
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM