Backbone chemical shift assignment of macrophage infectivity potentiator virulence factor of Trypanosoma cruzi.

FK506 binding protein FKBP-like protein Macrophage infectivity potentiator NMR resonance assignment Prolyl cis trans isomerase TcMIP Trypanosoma cruzi Virulence factor

Journal

Biomolecular NMR assignments
ISSN: 1874-270X
Titre abrégé: Biomol NMR Assign
Pays: Netherlands
ID NLM: 101472371

Informations de publication

Date de publication:
04 2019
Historique:
received: 03 07 2018
accepted: 14 09 2018
pubmed: 20 9 2018
medline: 30 7 2019
entrez: 20 9 2018
Statut: ppublish

Résumé

Chagas disease is a trypanosomiasis disease inflicted by Trypanosoma cruzi parasite. In Latin America, at least 10 million people are infected and annually, 10,000 casualties are deplored. Macrophage infectivity potentiator protein is one of the major virulence factors secreted by T. cruzi (TcMIP) in order to infect its host but little is known about its mechanism of action. Studies confer TcMIP an important role in the extracellular matrix transmigration and basal lamina penetration. Here, we report the backbone

Identifiants

pubmed: 30229449
doi: 10.1007/s12104-018-9844-1
pii: 10.1007/s12104-018-9844-1
doi:

Substances chimiques

Nitrogen Isotopes 0
Nitrogen-15 0
Protons 0
Protozoan Proteins 0
Virulence Factors 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

21-25

Références

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Auteurs

Juan M Lopez (JM)

Centro de Espectroscopia de Resonancia Magnética Nuclear (CERMN), Departamento de Ciencias - Química, Pontificia Universidad Católica del Perú, Lima, Peru. juan.lopez@pucp.edu.pe.

Ricardo Antiparra (R)

Centro de Espectroscopia de Resonancia Magnética Nuclear (CERMN), Departamento de Ciencias - Química, Pontificia Universidad Católica del Perú, Lima, Peru.
Laboratorio de Bioinformática y Biología Molecular, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.

Guy Lippens (G)

LISBP, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France.

Mirko Zimic (M)

Laboratorio de Bioinformática y Biología Molecular, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.

Patricia Sheen (P)

Laboratorio de Bioinformática y Biología Molecular, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.

Helena Maruenda (H)

Centro de Espectroscopia de Resonancia Magnética Nuclear (CERMN), Departamento de Ciencias - Química, Pontificia Universidad Católica del Perú, Lima, Peru.

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