Expression polymorphism at the ARPC4 locus links the actin cytoskeleton with quantitative disease resistance to Sclerotinia sclerotiorum in Arabidopsis thaliana.
Arabidopsis thaliana
Sclerotinia sclerotiorum
actin cytoskeleton
callose
expression polymorphism
fungal pathogen
genome-wide association mapping
quantitative disease resistance
Journal
The New phytologist
ISSN: 1469-8137
Titre abrégé: New Phytol
Pays: England
ID NLM: 9882884
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
13
09
2018
accepted:
25
10
2018
pubmed:
6
11
2018
medline:
28
2
2020
entrez:
6
11
2018
Statut:
ppublish
Résumé
Quantitative disease resistance (QDR) is a form of plant immunity widespread in nature, and the only one active against broad host range fungal pathogens. The genetic determinants of QDR are complex and largely unknown, and are thought to rely partly on genes controlling plant morphology and development. We used genome-wide association mapping in Arabidopsis thaliana to identify ARPC4 as associated with QDR against the necrotrophic fungal pathogen Sclerotinia sclerotiorum. Mutants impaired in ARPC4 showed enhanced susceptibility to S. sclerotiorum, defects in the structure of the actin filaments and in their responsiveness to S. sclerotiorum. Disruption of ARPC4 also alters callose deposition and the expression of defense-related genes upon S. sclerotiorum infection. Analysis of ARPC4 diversity in A. thaliana identified one haplotype (ARPC4
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
480-496Subventions
Organisme : FP7 Ideas: European Research Council
ID : ERC-StG-336808
Pays : International
Organisme : Agence Nationale de la Recherche
ID : ANR-10-KBBE-0005
Pays : International
Organisme : Laboratory of Excellence project TULIP
ID : ANR-10-LABX-41
Pays : International
Organisme : Laboratory of Excellence project TULIP
ID : ANR-11-IDEX-0002-02
Pays : International
Informations de copyright
© 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.