A Systematic Review of Patient- and Family-Level Inhaled Corticosteroid Adherence Interventions in Black/African Americans.


Journal

The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201
Titre abrégé: J Allergy Clin Immunol Pract
Pays: United States
ID NLM: 101597220

Informations de publication

Date de publication:
04 2019
Historique:
received: 24 12 2017
revised: 03 10 2018
accepted: 24 10 2018
pubmed: 6 11 2018
medline: 25 7 2020
entrez: 6 11 2018
Statut: ppublish

Résumé

Inhaled corticosteroid (ICS) adherence rates are suboptimal among adult black/African Americans. Comprehensive studies characterizing the effectiveness and the methodological approaches to the development of interventions to improve ICS adherence in adult black/African Americans have not been performed. Conduct a systematic review of patient/family-level interventions to improve ICS adherence in adult black/African Americans. We searched MEDLINE, EMBASE, Web of Science, and CINAHL from inception to August 2017 for English-language US studies enrolling at least 30% black/African Americans comparing patient/family-level ICS adherence interventions with any comparator. Two investigators independently selected, extracted data from, and rated risk of bias. We collected information on intervention characteristics and outcomes, and assessed whether studies were informed by behavior theory, stakeholder engagement, or both. Among 1661 abstracts identified, we reviewed 230 full-text articles and identified 4 randomized controlled trials (RCTs) and 1 quasi-experimental (pre-post design) study meeting criteria. Study participants (N range, 17-333) varied in mean age (22-47 years), proportion black/African Americans studied (71%-93%), and sex (69%-82% females). RCTs evaluated problem-solving classes, self-efficacy training, technology-based motivational interviewing program, and the use of patient advocates. The RCT testing self-efficacy training was the only intervention informed by both behavior theory and stakeholder engagement. All 4 RCTs compared interventions with active control and rated as medium risk of bias. No RCTs found a statistically significant improvement in adherence. Few studies assessing asthma adherence interventions focused on adult black/African-American populations. No RCTs demonstrated improved ICS adherence in participants. Future studies that are informed by behavior change theory and stakeholder engagement are needed.

Sections du résumé

BACKGROUND
Inhaled corticosteroid (ICS) adherence rates are suboptimal among adult black/African Americans. Comprehensive studies characterizing the effectiveness and the methodological approaches to the development of interventions to improve ICS adherence in adult black/African Americans have not been performed.
OBJECTIVES
Conduct a systematic review of patient/family-level interventions to improve ICS adherence in adult black/African Americans.
METHODS
We searched MEDLINE, EMBASE, Web of Science, and CINAHL from inception to August 2017 for English-language US studies enrolling at least 30% black/African Americans comparing patient/family-level ICS adherence interventions with any comparator. Two investigators independently selected, extracted data from, and rated risk of bias. We collected information on intervention characteristics and outcomes, and assessed whether studies were informed by behavior theory, stakeholder engagement, or both.
RESULTS
Among 1661 abstracts identified, we reviewed 230 full-text articles and identified 4 randomized controlled trials (RCTs) and 1 quasi-experimental (pre-post design) study meeting criteria. Study participants (N range, 17-333) varied in mean age (22-47 years), proportion black/African Americans studied (71%-93%), and sex (69%-82% females). RCTs evaluated problem-solving classes, self-efficacy training, technology-based motivational interviewing program, and the use of patient advocates. The RCT testing self-efficacy training was the only intervention informed by both behavior theory and stakeholder engagement. All 4 RCTs compared interventions with active control and rated as medium risk of bias. No RCTs found a statistically significant improvement in adherence.
CONCLUSIONS
Few studies assessing asthma adherence interventions focused on adult black/African-American populations. No RCTs demonstrated improved ICS adherence in participants. Future studies that are informed by behavior change theory and stakeholder engagement are needed.

Identifiants

pubmed: 30395992
pii: S2213-2198(18)30707-4
doi: 10.1016/j.jaip.2018.10.036
pmc: PMC7957831
mid: NIHMS1664413
pii:
doi:

Substances chimiques

Adrenal Cortex Hormones 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1184-1193.e3

Subventions

Organisme : NIMHD NIH HHS
ID : U54 MD012530
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2018 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

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Auteurs

Isaretta L Riley (IL)

Duke University School of Medicine, Durham, NC. Electronic address: isaretta.riley@duke.edu.

Beverly Murphy (B)

Duke University School of Medicine, Durham, NC.

Zayd Razouki (Z)

Mayo School of Medicine, Rochester, Minn.

Jerry A Krishnan (JA)

University of Illinois Hospital & Health Sciences System, Chicago, Ill.

Andrea Apter (A)

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.

Sande Okelo (S)

The David Geffen School of Medicine at UCLA, Los Angeles, Calif.

Monica Kraft (M)

University of Arizona School of Medicine, Tuscson, Ariz.

Cindy Feltner (C)

University of North Carolina at Chapel Hill, Chapel Hill, NC.

Loretta G Que (LG)

Duke University School of Medicine, Durham, NC.

L Ebony Boulware (LE)

Duke University School of Medicine, Durham, NC.

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