Propeptide glycosylation and galectin-3 binding decrease proteolytic activation of human proMMP-9/progelatinase B.
Amino Acid Sequence
Blood Proteins
Case-Control Studies
Congenital Disorders of Glycosylation
/ metabolism
Enzyme Activation
Enzyme Precursors
/ metabolism
Galectin 3
/ metabolism
Galectins
Gelatinases
/ metabolism
Glycosylation
Humans
Leukocyte Elastase
/ metabolism
Matrix Metalloproteinase 3
/ metabolism
Matrix Metalloproteinase 9
/ metabolism
Proteolysis
N-linked glycosylation
galectin-3
matrix metalloproteinase-9
propeptide
proteolytic activation
Journal
The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
05
07
2018
revised:
21
09
2018
accepted:
09
11
2018
pubmed:
14
11
2018
medline:
18
12
2019
entrez:
14
11
2018
Statut:
ppublish
Résumé
Matrix metalloproteinases (MMPs) are secreted as proenzymes, containing propeptides that interact with the catalytic zinc, thereby controlling MMP activation. The MMP-9 propeptide is unique in the MMP family because of its post-translational modification with an N-linked oligosaccharide. ProMMP-9 activation by MMP-3 occurs stepwise by cleavage of the propeptide in an aminoterminal (pro-AT) and carboxyterminal (pro-CT) peptide. We chemically synthesized aglycosyl pro-AT and pro-CT and purified recombinant glycosylated pro-AT
Identifiants
pubmed: 30422384
doi: 10.1111/febs.14698
pmc: PMC7379967
doi:
Substances chimiques
Blood Proteins
0
Enzyme Precursors
0
Galectin 3
0
Galectins
0
LGALS3 protein, human
0
Leukocyte Elastase
EC 3.4.21.37
Gelatinases
EC 3.4.24.-
progelatinase
EC 3.4.24.-
MMP3 protein, human
EC 3.4.24.17
Matrix Metalloproteinase 3
EC 3.4.24.17
MMP9 protein, human
EC 3.4.24.35
Matrix Metalloproteinase 9
EC 3.4.24.35
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
930-945Informations de copyright
© 2018 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
Références
Acta Crystallogr D Biol Crystallogr. 2002 Jul;58(Pt 7):1182-92
pubmed: 12077439
World J Biol Chem. 2011 Jan 26;2(1):14-24
pubmed: 21537473
PLoS One. 2010 Jun 16;5(6):e11043
pubmed: 20585385
J Neuroimmunol. 1999 Feb 1;94(1-2):1-14
pubmed: 10376931
Biochemistry. 1994 Nov 29;33(47):14109-14
pubmed: 7947821
Biochemistry. 2008 Feb 26;47(8):2689-99
pubmed: 18237197
Cell. 1998 May 1;93(3):411-22
pubmed: 9590175
J Biol Chem. 2004 Mar 19;279(12):10841-7
pubmed: 14672941
Structure. 2007 Oct;15(10):1227-36
pubmed: 17937912
Eur J Biochem. 1998 Nov 15;258(1):37-43
pubmed: 9851689
PLoS One. 2018 Jan 12;13(1):e0191157
pubmed: 29329315
Nucleic Acids Res. 2014 May;42(9):5518-31
pubmed: 24627221
Biochim Biophys Acta. 1995 Sep 6;1251(2):99-108
pubmed: 7669817
Crit Rev Biochem Mol Biol. 2013 May-Jun;48(3):222-72
pubmed: 23547785
Nat Rev Drug Discov. 2014 Dec;13(12):904-27
pubmed: 25376097
J Biol Chem. 1997 Oct 10;272(41):25628-35
pubmed: 9325284
Nat Methods. 2013 Mar;10(3):211-20
pubmed: 23443633
Microbiol Immunol. 2018 Mar;62(3):168-175
pubmed: 29328525
Sci Transl Med. 2016 Nov 9;8(364):364ra152
pubmed: 27831901
Nat Rev Cancer. 2006 Mar;6(3):227-39
pubmed: 16498445
Cancer Res. 1995 Jun 15;55(12):2548-55
pubmed: 7780967
Brain. 2003 Jun;126(Pt 6):1371-81
pubmed: 12764058
Eur J Biochem. 1998 Apr 1;253(1):67-75
pubmed: 9578462
Cell. 2010 Apr 2;141(1):52-67
pubmed: 20371345
J Biol Chem. 1992 Apr 5;267(10):6776-81
pubmed: 1313021
Cell. 1994 Feb 25;76(4):597-8
pubmed: 8124704
J Biol Chem. 1992 Oct 25;267(30):21712-9
pubmed: 1400481
J Biol Chem. 2012 Aug 10;287(33):27601-13
pubmed: 22730324
Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11109-14
pubmed: 23776237
J Biol Chem. 2006 Jul 7;281(27):18626-37
pubmed: 16672230
Nat Rev Drug Discov. 2007 Jun;6(6):480-98
pubmed: 17541420
J Clin Invest. 2000 Sep;106(5):627-8
pubmed: 10974013
Glycobiology. 2003 Nov;13(11):755-63
pubmed: 12881409
Biochemistry. 1999 Oct 19;38(42):13937-50
pubmed: 10529240
Crit Rev Biochem Mol Biol. 1997;32(1):1-100
pubmed: 9063619
J Invest Dermatol. 2007 May;127(5):1115-25
pubmed: 17195012
Biochem J. 2016 Jun 1;473(11):1471-82
pubmed: 27234584
Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20262-7
pubmed: 18077379
Proc Natl Acad Sci U S A. 1990 Jul;87(14):5578-82
pubmed: 2164689
Mol Med. 2010 May-Jun;16(5-6):159-66
pubmed: 20111696
Biochem Soc Trans. 1997 Nov;25(4):1177-84
pubmed: 9449971
J Inherit Metab Dis. 2017 Jul;40(4):569-586
pubmed: 28484880
Biol Chem. 2003 May;384(5):825-31
pubmed: 12817480
Thromb Haemost. 2001 Jul;86(1):324-33
pubmed: 11487021
J Biol Chem. 1992 Feb 25;267(6):3581-4
pubmed: 1371271
Eur J Biochem. 1997 Sep 1;248(2):369-73
pubmed: 9346290
Traffic. 2015 Oct;16(10):1108-26
pubmed: 26207422
Cancer Cell. 2004 Oct;6(4):409-21
pubmed: 15488763
Oral Oncol. 2017 Aug;71:156-162
pubmed: 28688684
J Cell Physiol. 1993 Dec;157(3):587-93
pubmed: 8253870
Cancer Res. 2000 Sep 1;60(17):4745-51
pubmed: 10987280
Biochim Biophys Acta. 2001 Oct 3;1528(2-3):61-73
pubmed: 11687291
Biochem Biophys Res Commun. 2008 May 16;369(4):1215-20
pubmed: 18355442
J Mol Biol. 2002 Jul 26;320(5):1065-79
pubmed: 12126625
FEBS Lett. 2012 Dec 14;586(24):4264-9
pubmed: 23123160
J Leukoc Biol. 2007 Apr;81(4):870-92
pubmed: 17185359
J Biol Chem. 2017 Oct 27;292(43):17963-17974
pubmed: 28860188
Biochemistry. 1994 Jan 11;33(1):17-22
pubmed: 8286336
Biochemistry. 2000 Dec 26;39(51):15695-704
pubmed: 11123894
Biochemistry. 2006 Dec 26;45(51):15249-58
pubmed: 17176047