Jennifer Vandooren

Affiliations

Department of Microbiology and Immunology, Laboratory of Immunobiology, Rega Institute, Katholieke Universiteit (KU) Leuven, 3000 Leuven, Belgium.

Publications (22)

Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Evelien Houben , Kris Janssens , Doryssa Hermans , Jennifer Vandooren , Chris Van den Haute , Melissa Schepers , Tim Vanmierlo , Ivo Lambrichts , Jack van Horssen , Veerle Baekelandt , Ghislain Opdenakker , Wia Baron , Bieke Broux , Helena Slaets , Niels Hellings

Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019.

Clinical & translational immunology

Avec: Mieke Metzemaekers , Seppe Cambier , Marfa Blanter , Jennifer Vandooren , Ana Carolina de Carvalho , Bert Malengier-Devlies , Lore Vanderbeke , Cato Jacobs , Sofie Coenen , Erik Martens , Noëmie Pörtner , Lotte Vanbrabant , Pierre Van Mol , Yannick Van Herck , Nathalie Van Aerde , Greet Hermans , Jan Gunst , Alexandre Borin , Bruna Toledo N Pereira , Arilson Bernardo Dos Sp Gomes , Stéfanie Primon Muraro , Gabriela Fabiano de Souza , Alessandro S Farias , José Luiz Proenca-Modena , Marco Aurélio R Vinolo , Auteur inconnu , Pedro Elias Marques , Carine Wouters , Els Wauters , Sofie Struyf , Patrick Matthys , Ghislain Opdenakker , Rafael Elias Marques , Joost Wauters , Mieke Gouwy , Paul Proost

Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases.

Frontiers in immunology

Avec: Jennifer Vandooren , Rafaela Vaz Sousa Pereira , Estefania Ugarte-Berzal , Vasily Rybakin , Sam Noppen , Melissa R Stas , Eline Bernaerts , Eva Ganseman , Mieke Metzemaekers , Dominique Schols , Paul Proost , Ghislain Opdenakker

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Avec: Elisa Nuti , Armando Rossello , Doretta Cuffaro , Caterina Camodeca , Jens Van Bael , Dries van der Maat , Erik Martens , Pierre Fiten , Rafaela Vaz Sousa Pereira , Estefania Ugarte-Berzal , Mieke Gouwy , Ghislain Opdenakker , Jennifer Vandooren

Gelatinase B/matrix metalloproteinase-9 and other neutrophil proteases switch off interleukin-2 activity.

The Biochemical journal

Avec: Vasily Rybakin , Melissa Stas , Estefania Ugarte-Berzal , Sam Noppen , Jennifer Vandooren , Ilse Van Aelst , Sandra Liekens , Paul Proost , Ghislain Opdenakker

HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.

Antiviral research

Avec: Caroline S Foo , Rana Abdelnabi , Suzanne J F Kaptein , Xin Zhang , Sebastiaan Ter Horst , Raf Mols , Leen Delang , Joana Rocha-Pereira , Lotte Coelmont , Pieter Leyssen , Kai Dallmeier , Valentijn Vergote , Elisabeth Heylen , Laura Vangeel , Arnab K Chatterjee , Pieter P Annaert , Patrick F Augustijns , Steven De Jonghe , Dirk Jochmans , Mieke Gouwy , Seppe Cambier , Jennifer Vandooren , Paul Proost , Christine van Laer , Birgit Weynand , Johan Neyts

Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing.

Frontiers in immunology

Avec: Rafaela Vaz Sousa Pereira , Mostafa EzEldeen , Estefania Ugarte-Berzal , Erik Martens , Bert Malengier-Devlies , Jennifer Vandooren , Jan Jeroen Vranckx , Patrick Matthys , Ghislain Opdenakker

Novel high-yield potato protease inhibitor panels block a wide array of proteases involved in viral infection and crucial tissue damage.

Journal of molecular medicine (Berlin, Germany)

Avec: Nienke Visser , Laure C M Herreman , Jennifer Vandooren , Rafaela Vaz Sousa Pereira , Ghislain Opdenakker , Robin E J Spelbrink , Maarten H Wilbrink , Edwin Bremer , Reinoud Gosens , Martijn C Nawijn , Heidi H van der Ende-Metselaar , Jolanda M Smit , Marc C Laus , Jon D Laman

Homotrimeric MMP-9 is an active hitchhiker on alpha-2-macroglobulin partially escaping protease inhibition and internalization through LRP-1.

Cellular and molecular life sciences : CMLS

Avec: Xena Serifova , Estefania Ugarte-Berzal , Ghislain Opdenakker , Jennifer Vandooren

EDTA/gelatin zymography method to identify C1s versus activated MMP-9 in plasma and immune complexes of patients with systemic lupus erythematosus.

Journal of cellular and molecular medicine

Avec: Estefania Ugarte-Berzal , Erik Martens , Lise Boon , Jennifer Vandooren , Daniel Blockmans , Paul Proost , Ghislain Opdenakker

Zinc-Calcium-Fluoride Bioglass-Based Innovative Multifunctional Dental Adhesive with Thick Adhesive Resin Film Thickness.

ACS applied materials & interfaces

Avec: Chenmin Yao , Mohammed H Ahmed , Xin Li , Ivana Nedeljkovic , Jennifer Vandooren , Ben Mercelis , Fei Zhang , Kirsten L Van Landuyt , Cui Huang , Bart Van Meerbeek

Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza.

JCI insight

Avec: Seppe Cambier , Mieke Metzemaekers , Ana Carolina de Carvalho , Amber Nooyens , Cato Jacobs , Lore Vanderbeke , Bert Malengier-Devlies , Mieke Gouwy , Elisabeth Heylen , Philippe Meersseman , Greet Hermans , Els Wauters , Alexander Wilmer , Auteur inconnu , Dominique Schols , Patrick Matthys , Ghislain Opdenakker , Rafael Elias Marques , Joost Wauters , Jennifer Vandooren , Paul Proost

Citrullination as a novel posttranslational modification of matrix metalloproteinases.

Matrix biology : journal of the International Society for Matrix Biology

Avec: Lise Boon , Estefania Ugarte-Berzal , Erik Martens , Pierre Fiten , Jennifer Vandooren , Rik Janssens , Marfa Blanter , Karen Yu , Mieke Boon , Sofie Struyf , Paul Proost , Ghislain Opdenakker

Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer's Disease.

Pharmaceuticals (Basel, Switzerland)

Avec: Lidia Ciccone , Jennifer Vandooren , Susanna Nencetti , Elisabetta Orlandini

Protease propeptide structures, mechanisms of activation, and functions.

Critical reviews in biochemistry and molecular biology

Avec: Lise Boon , Estefania Ugarte-Berzal , Jennifer Vandooren , Ghislain Opdenakker

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus.

Frontiers in immunology

Avec: Estefania Ugarte-Berzal , Lise Boon , Erik Martens , Vasily Rybakin , Daniel Blockmans , Jennifer Vandooren , Paul Proost , Ghislain Opdenakker

Propeptide glycosylation and galectin-3 binding decrease proteolytic activation of human proMMP-9/progelatinase B.

The FEBS journal

Avec: Lise Boon , Estefania Ugarte-Berzal , Erik Martens , Jennifer Vandooren , Vasily Rybakin , Didier Colau , Monica Gordon-Alonso , Pierre van der Bruggen , Walter Stöcker , Christoph Becker-Pauly , Peter Witters , Eva Morava , Jaak Jaeken , Paul Proost , Ghislain Opdenakker

From ELISA to Immunosorbent Tandem Mass Spectrometry Proteoform Analysis: The Example of CXCL8/Interleukin-8.

Frontiers in immunology

Avec: Mieke Metzemaekers , Sara Abouelasrar Salama , Jennifer Vandooren , Anneleen Mortier , Rik Janssens , Sofie Vandendriessche , Eva Ganseman , Erik Martens , Mieke Gouwy , Barbara Neerinckx , Patrick Verschueren , Lien De Somer , Carine Wouters , Sofie Struyf , Ghislain Opdenakker , Jo Van Damme , Paul Proost

Alpha-2-Macroglobulin in Inflammation, Immunity and Infections.

Frontiers in immunology

Avec: Jennifer Vandooren , Yoshifumi Itoh

Proteoform Analysis of Matrix Metalloproteinase-9/Gelatinase B and Discovery of Its Citrullination in Rheumatoid Arthritis Synovial Fluids.

Frontiers in immunology

Avec: Bernard Grillet , Karen Yu , Estefania Ugarte-Berzal , Rik Janssens , Rafaela Vaz Sousa Pereira , Lise Boon , Erik Martens , Nele Berghmans , Isabelle Ronsse , Ilse Van Aelst , Pierre Fiten , René Conings , Jennifer Vandooren , Patrick Verschueren , Jo Van Damme , Paul Proost , Ghislain Opdenakker

Chlorite-Oxidized Oxyamylose (COAM) Has Antibacterial Activity and Positively Affects Skin Wound Healing.

Journal of inflammation research

Avec: Rafaela Vaz Sousa Pereira , Estefania Ugarte-Berzal , Jennifer Vandooren , Karin Nylander , Erik Martens , Lieve Van Mellaert , Jo Van Damme , Jan Jeroen Vranckx , Patrick Matthys , Tiina Alamäe , Mia Phillipson , Triinu Visnapuu , Ghislain Opdenakker

Protection of stromal cell-derived factor-1 SDF-1/CXCL12 against proteases yields improved skin wound healing.

Frontiers in immunology

Avec: Rafaela Vaz Sousa Pereira , Mostafa EzEldeen , Estefania Ugarte-Berzal , Jennifer Vandooren , Erik Martens , Mieke Gouwy , Eva Ganseman , Jo Van Damme , Patrick Matthys , Jan Jeroen Vranckx , Paul Proost , Ghislain Opdenakker

Réseau de co-auteurs

Ghislain Opdenakker 18 collaborations

Estefania Ugarte-Berzal 13 collaborations

Paul Proost 12 collaborations

Erik Martens 11 collaborations

Rafaela Vaz Sousa Pereira 7 collaborations

Mieke Gouwy 6 collaborations

Lise Boon 6 collaborations

Patrick Matthys 5 collaborations

Mieke Metzemaekers 4 collaborations

Vasily Rybakin 4 collaborations

Jo Van Damme 4 collaborations

Seppe Cambier 3 collaborations

Bert Malengier-Devlies 3 collaborations

Sofie Struyf 3 collaborations

Eva Ganseman 3 collaborations

Pierre Fiten 3 collaborations

Jan Jeroen Vranckx 3 collaborations

Rik Janssens 3 collaborations

Marfa Blanter 2 collaborations

Ana Carolina de Carvalho 2 collaborations

Lore Vanderbeke 2 collaborations

Cato Jacobs 2 collaborations

Greet Hermans 2 collaborations

None None 2 collaborations

Carine Wouters 2 collaborations

Els Wauters 2 collaborations

Rafael Elias Marques 2 collaborations

Joost Wauters 2 collaborations

Sam Noppen 2 collaborations

Dominique Schols 2 collaborations

Ilse Van Aelst 2 collaborations

Elisabeth Heylen 2 collaborations

Mostafa EzEldeen 2 collaborations

Daniel Blockmans 2 collaborations

Karen Yu 2 collaborations

Patrick Verschueren 2 collaborations

Evelien Houben 1 collaboration

Kris Janssens 1 collaboration

Doryssa Hermans 1 collaboration

Chris Van den Haute 1 collaboration

Melissa Schepers 1 collaboration

Tim Vanmierlo 1 collaboration

Ivo Lambrichts 1 collaboration

Jack van Horssen 1 collaboration

Veerle Baekelandt 1 collaboration

Wia Baron 1 collaboration

Bieke Broux 1 collaboration

Helena Slaets 1 collaboration

Niels Hellings 1 collaboration

Sofie Coenen 1 collaboration

Noëmie Pörtner 1 collaboration

Lotte Vanbrabant 1 collaboration

Pierre Van Mol 1 collaboration

Yannick Van Herck 1 collaboration

Nathalie Van Aerde 1 collaboration

Jan Gunst 1 collaboration

Alexandre Borin 1 collaboration

Bruna Toledo N Pereira 1 collaboration

Arilson Bernardo Dos Sp Gomes 1 collaboration

Stéfanie Primon Muraro 1 collaboration

Gabriela Fabiano de Souza 1 collaboration

Alessandro S Farias 1 collaboration

José Luiz Proenca-Modena 1 collaboration

Marco Aurélio R Vinolo 1 collaboration

Pedro Elias Marques 1 collaboration

Melissa R Stas 1 collaboration

Eline Bernaerts 1 collaboration

Elisa Nuti 1 collaboration

Armando Rossello 1 collaboration

Doretta Cuffaro 1 collaboration

Caterina Camodeca 1 collaboration

Jens Van Bael 1 collaboration

Dries van der Maat 1 collaboration

Melissa Stas 1 collaboration

Sandra Liekens 1 collaboration

Caroline S Foo 1 collaboration

Rana Abdelnabi 1 collaboration

Suzanne J F Kaptein 1 collaboration

Xin Zhang 1 collaboration

Sebastiaan Ter Horst 1 collaboration

Raf Mols 1 collaboration

Leen Delang 1 collaboration

Joana Rocha-Pereira 1 collaboration

Lotte Coelmont 1 collaboration

Pieter Leyssen 1 collaboration

Kai Dallmeier 1 collaboration

Valentijn Vergote 1 collaboration

Laura Vangeel 1 collaboration

Arnab K Chatterjee 1 collaboration

Pieter P Annaert 1 collaboration

Patrick F Augustijns 1 collaboration

Steven De Jonghe 1 collaboration

Dirk Jochmans 1 collaboration

Christine van Laer 1 collaboration

Birgit Weynand 1 collaboration

Johan Neyts 1 collaboration

Nienke Visser 1 collaboration

Laure C M Herreman 1 collaboration

Robin E J Spelbrink 1 collaboration

Maarten H Wilbrink 1 collaboration

Edwin Bremer 1 collaboration

Reinoud Gosens 1 collaboration

Martijn C Nawijn 1 collaboration

Heidi H van der Ende-Metselaar 1 collaboration

Jolanda M Smit 1 collaboration

Marc C Laus 1 collaboration

Jon D Laman 1 collaboration

Xena Serifova 1 collaboration

Chenmin Yao 1 collaboration

Mohammed H Ahmed 1 collaboration

Xin Li 1 collaboration

Ivana Nedeljkovic 1 collaboration

Ben Mercelis 1 collaboration

Fei Zhang 1 collaboration

Kirsten L Van Landuyt 1 collaboration

Cui Huang 1 collaboration

Bart Van Meerbeek 1 collaboration

Amber Nooyens 1 collaboration

Philippe Meersseman 1 collaboration

Alexander Wilmer 1 collaboration

Mieke Boon 1 collaboration

Lidia Ciccone 1 collaboration

Susanna Nencetti 1 collaboration

Elisabetta Orlandini 1 collaboration

Didier Colau 1 collaboration

Monica Gordon-Alonso 1 collaboration

Pierre van der Bruggen 1 collaboration

Walter Stöcker 1 collaboration

Christoph Becker-Pauly 1 collaboration

Peter Witters 1 collaboration

Eva Morava 1 collaboration

Jaak Jaeken 1 collaboration

Sara Abouelasrar Salama 1 collaboration

Anneleen Mortier 1 collaboration

Sofie Vandendriessche 1 collaboration

Barbara Neerinckx 1 collaboration

Lien De Somer 1 collaboration

Yoshifumi Itoh 1 collaboration

Bernard Grillet 1 collaboration

Nele Berghmans 1 collaboration

Isabelle Ronsse 1 collaboration

René Conings 1 collaboration

Karin Nylander 1 collaboration

Lieve Van Mellaert 1 collaboration

Tiina Alamäe 1 collaboration

Mia Phillipson 1 collaboration

Triinu Visnapuu 1 collaboration