Impedimetric mechanism study of horseradish peroxidase at low and high concentrations of hydrogen peroxide based on graphene/sol-gel/horseradish peroxidase.


Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
15 Feb 2019
Historique:
received: 09 10 2018
revised: 09 11 2018
accepted: 11 11 2018
pubmed: 16 11 2018
medline: 19 4 2019
entrez: 16 11 2018
Statut: ppublish

Résumé

A novel electrochemical modified electrode for the impedimetric mechanism study of horseradish peroxidase and hydrogen peroxide was proposed based on immobilizing horseradish peroxidase/3‑(trimethoxysilyl) propylamine/graphene on glassy carbon electrode (HRP/TMSPA/Gr/GCE). Cyclic voltammetry and SEM were utilized to corroborate the successful stepwise assemblage procedure of the electrode. The electrochemical impedance spectroscopy measurements revealed that the charge transfer resistance increases at low concentrations and significantly decreases at high concentrations after enzymatic reaction with hydrogen peroxide. The mechanism study of the horseradish peroxidase and hydrogen peroxide were also investigated by electrochemical impedance spectroscopy.

Identifiants

pubmed: 30439427
pii: S0141-8130(18)35407-2
doi: 10.1016/j.ijbiomac.2018.11.091
pii:
doi:

Substances chimiques

Enzymes, Immobilized 0
Nanotubes, Carbon 0
Graphite 7782-42-5
Hydrogen Peroxide BBX060AN9V
Horseradish Peroxidase EC 1.11.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

677-681

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Nader Amini (N)

Environmental Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran; Department of Analytical Chemistry, Razi University, Kermanshah, Iran. Electronic address: naderamini95@yahoo.com.

Mojtaba Shamsipur (M)

Department of Analytical Chemistry, Razi University, Kermanshah, Iran. Electronic address: mshamsipur@yahoo.com.

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Classifications MeSH