Methadone therapy modulate the dendritic cells of heroin addicts.
Adult
CD11c Antigen
/ metabolism
Cell Separation
Dendritic Cells
/ drug effects
Down-Regulation
/ drug effects
Flow Cytometry
HLA-DR Antigens
/ metabolism
Heroin Dependence
/ drug therapy
Humans
Immunomodulation
Interleukin-3 Receptor alpha Subunit
/ metabolism
Male
Methadone
/ therapeutic use
Opiate Substitution Treatment
Young Adult
Dendritic cells
Detoxification drugs
Heroin
Methadone
Journal
International immunopharmacology
ISSN: 1878-1705
Titre abrégé: Int Immunopharmacol
Pays: Netherlands
ID NLM: 100965259
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
24
09
2018
revised:
13
11
2018
accepted:
27
11
2018
pubmed:
7
12
2018
medline:
6
5
2019
entrez:
7
12
2018
Statut:
ppublish
Résumé
Evidence from various studies suggests that narcotics abuse may exert adverse immunomodulatory effects on immune responses. The aim of this research was to understand the effects of detoxification with methadone on the percentage of dendritic cells (DCs) and expression of its markers in heroin addicts. In this study, myeloid DCs (CD11c
Identifiants
pubmed: 30521961
pii: S1567-5769(18)30723-9
doi: 10.1016/j.intimp.2018.11.047
pii:
doi:
Substances chimiques
CD11c Antigen
0
HLA-DR Antigens
0
Interleukin-3 Receptor alpha Subunit
0
Methadone
UC6VBE7V1Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
330-335Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.