Molecular conformation affects the interaction of the

Pseudomonas aeruginosa (P. aeruginosa) cell communication hydrogen bond lipid A membrane dynamics molecular dynamics outer membrane outer membrane vesicle biogenesis quorum sensing small molecule

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
25 01 2019
Historique:
received: 28 11 2018
revised: 10 12 2018
pubmed: 20 12 2018
medline: 9 5 2019
entrez: 20 12 2018
Statut: ppublish

Résumé

Gram-negative bacteria produce outer-membrane vesicles (OMVs) that package genetic elements, virulence factors, and cell-to-cell communication signaling compounds. Despite their importance in many disease-related processes, how these versatile structures are formed is incompletely understood. A self-produced secreted small molecule, the

Identifiants

pubmed: 30563840
pii: S0021-9258(20)38848-7
doi: 10.1074/jbc.AC118.006844
pmc: PMC6349108
pii:
doi:

Substances chimiques

Bacterial Outer Membrane Proteins 0
Quinolones 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1089-1094

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI121848
Pays : United States

Informations de copyright

© 2019 Li et al.

Références

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Auteurs

Ao Li (A)

Departments of Mechanical Engineering, Binghamton, New York 13902.

Jeffrey W Schertzer (JW)

Biological Sciences, Binghamton, New York 13902; Binghamton Biofilm Research Center, Binghamton University, The State University of New York, Binghamton, New York 13902.

Xin Yong (X)

Departments of Mechanical Engineering, Binghamton, New York 13902; Binghamton Biofilm Research Center, Binghamton University, The State University of New York, Binghamton, New York 13902. Electronic address: xyong@binghamton.edu.

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Classifications MeSH