Actively personalized vaccination trial for newly diagnosed glioblastoma.
Adult
Aged
Antigens, Neoplasm
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
Cancer Vaccines
/ immunology
Epitopes, T-Lymphocyte
/ immunology
Female
Glioblastoma
/ diagnosis
HLA-A Antigens
/ immunology
Humans
Immunologic Memory
/ immunology
Male
Middle Aged
Precision Medicine
/ methods
T-Lymphocytes, Helper-Inducer
/ immunology
Treatment Outcome
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
08
05
2018
accepted:
19
11
2018
pubmed:
21
12
2018
medline:
8
5
2019
entrez:
21
12
2018
Statut:
ppublish
Résumé
Patients with glioblastoma currently do not sufficiently benefit from recent breakthroughs in cancer treatment that use checkpoint inhibitors
Identifiants
pubmed: 30568303
doi: 10.1038/s41586-018-0810-y
pii: 10.1038/s41586-018-0810-y
doi:
Substances chimiques
Antigens, Neoplasm
0
Cancer Vaccines
0
Epitopes, T-Lymphocyte
0
HLA-A Antigens
0
Types de publication
Clinical Trial, Phase I
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
240-245Subventions
Organisme : Medical Research Council
ID : MR/P024351/1
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : ErratumIn
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