Influenza B virus infection complicated by life-threatening pericarditis: a unique case-report and literature review.
Congenital heart disease with pulmonary hyper flow
Down syndrome
Pericardial effusion
Pericarditis
Type B influenza virus
Vaccination
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
10 Jan 2019
10 Jan 2019
Historique:
received:
05
03
2018
accepted:
10
12
2018
entrez:
12
1
2019
pubmed:
12
1
2019
medline:
26
2
2019
Statut:
epublish
Résumé
Acute pericarditis may occur frequently after viral infections. To our knowledge, influenza B virus infection complicated by pericarditis without myocardial involvement has never been reported. We report the first case of life-threatening pericarditis caused by influenza B virus infection. A 48-years-old woman with trisomy 21 and ostium primum atrial septal defect was transferred from Cardiology to our Internal Medicine Department for severe pericardial effusion unresponsive to ibuprofen and colchicine. Based on the recent patient history of flu-like syndrome, and presence of pleuro-pericardial effusion, a viral etiology was suspected. Laboratory evaluation and molecular assay of tracheal aspirate identified influenza B virus. Therefore, the ongoing metilprednisolone and colchicine therapy was implemented with oseltamivir with progressive patient improvement and no evidence of pericardial effusion recurrence during follow-up. Especially in autumn and winter periods, clinicians should include Influenza B virus infection on differential diagnosis of pericarditis with large pericardial effusion.
Sections du résumé
BACKGROUND
BACKGROUND
Acute pericarditis may occur frequently after viral infections. To our knowledge, influenza B virus infection complicated by pericarditis without myocardial involvement has never been reported. We report the first case of life-threatening pericarditis caused by influenza B virus infection.
CASE PRESENTATION
METHODS
A 48-years-old woman with trisomy 21 and ostium primum atrial septal defect was transferred from Cardiology to our Internal Medicine Department for severe pericardial effusion unresponsive to ibuprofen and colchicine. Based on the recent patient history of flu-like syndrome, and presence of pleuro-pericardial effusion, a viral etiology was suspected. Laboratory evaluation and molecular assay of tracheal aspirate identified influenza B virus. Therefore, the ongoing metilprednisolone and colchicine therapy was implemented with oseltamivir with progressive patient improvement and no evidence of pericardial effusion recurrence during follow-up.
CONCLUSIONS
CONCLUSIONS
Especially in autumn and winter periods, clinicians should include Influenza B virus infection on differential diagnosis of pericarditis with large pericardial effusion.
Identifiants
pubmed: 30630424
doi: 10.1186/s12879-018-3606-7
pii: 10.1186/s12879-018-3606-7
pmc: PMC6327550
doi:
Substances chimiques
Antiviral Agents
0
Oseltamivir
20O93L6F9H
Ibuprofen
WK2XYI10QM
Methylprednisolone
X4W7ZR7023
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
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