Proximal Tubule

Animals Formoterol Fumarate / pharmacology Kidney Tubules, Proximal / drug effects Male Mice Mitochondria / drug effects Receptors, Adrenergic, beta-2 / metabolism Recovery of Function / drug effects Reperfusion Injury / metabolism Signal Transduction / drug effects

Journal

The Journal of pharmacology and experimental therapeutics
ISSN: 1521-0103
Titre abrégé: J Pharmacol Exp Ther
Pays: United States
ID NLM: 0376362

Informations de publication

Date de publication:
04 2019
Historique:
received: 10 08 2018
accepted: 04 01 2019
pubmed: 3 2 2019
medline: 27 12 2019
entrez: 3 2 2019
Statut: ppublish

Résumé

Acute kidney injury (AKI) is the rapid loss of renal function after an insult, and renal proximal tubule cells (RPTCs) are central to the pathogenesis of AKI. The

Identifiants

DOI: 10.1124/jpet.118.252833 PMID: 30709866
pubmed: 30709866
pii: jpet.118.252833
doi: 10.1124/jpet.118.252833
doi:

Substances chimiques

Receptors, Adrenergic, beta-2 0
Formoterol Fumarate W34SHF8J2K

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

173-180

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES006694
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM084147
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007249
Pays : United States
Organisme : NIDDK NIH HHS
ID : F30 DK104550
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103542
Pays : United States

Informations de copyright

U.S. Government work not protected by U.S. copyright.

Auteurs

Robert B Cameron (RB)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Whitney S Gibbs (WS)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Siennah R Miller (SR)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Tess V Dupre (TV)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Judit Megyesi (J)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Craig C Beeson (CC)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.).

Rick G Schnellmann (RG)

Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (R.B.C., W.S.G., C.C.B.); College of Pharmacy, University of Arizona (R.B.C., W.S.G., S.R.M., T.V.D., R.G.S.), and Southern Arizona VA Healthcare System (R.G.S.), Tuscon, Arizona; and Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (J.M.) schnell@pharmacy.arizona.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Proximal Tubule
questionsmedicales.fr › Composés chimiques organiques › Amines › Aminoalcools › Éthanolamines › Fumarate de formotérol › Proximal Tubule
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Néphrons › Tubules rénaux › Tubules contournés proximaux › Proximal Tubule
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Proximal Tubule
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › Proximal Tubule
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs catécholaminergiques › Récepteurs adrénergiques › Récepteurs bêta-adrénergiques › Récepteurs bêta-2 adrénergiques › Proximal Tubule
questionsmedicales.fr › Phénomènes biologiques › Récupération fonctionnelle › Proximal Tubule
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Complications postopératoires › Lésion d'ischémie-reperfusion › Proximal Tubule
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Proximal Tubule