Rick G Schnellmann

Affiliations

Department of Pharmacology and Toxicology, College of Pharmacy (E.C.S., N.E.S., K.H.C., R.G.S.), Department of Neurosciences, College of Medicine (E.C.S., R.G.S.), Southwest Environmental Health Science Center (R.G.S.), and Center for Innovation in Brain Science (R.G.S.), University of Arizona, Tucson, Arizona; and Southern Arizona VA Health Care System, Tucson, Arizona (R.G.S.) schnell@pharmacy.arizona.edu.

ORCID: 0000-0001-7518-0876

Publications (37)

5-hydroxytryptamine 1F Receptor Agonist Induces Mitochondrial Biogenesis and Promotes Recovery from Spinal Cord Injury.

The Journal of pharmacology and experimental therapeutics

Avec: Epiphani C Simmons , Natalie E Scholpa , Kristan H Cleveland , Rick G Schnellmann

Repeated Administration of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Attenuates the Chronic Inflammatory Response to Experimental Stroke.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Danielle A Becktel , Jacob C Zbesko , Jennifer B Frye , Amanda G Chung , Megan Hayes , Kylie Calderon , Jeffrey W Grover , Anna Li , Frankie G Garcia , Marco A Tavera-Garcia , Rick G Schnellmann , Hsin-Jung Joyce Wu , Thuy-Vi V Nguyen , Kristian P Doyle

Isolation and monoculture of functional primary astrocytes from the adult mouse spinal cord.

Frontiers in neuroscience

Avec: Ingrid L Peterson , Austin D Thompson , Natalie E Scholpa , Tally Largent-Milnes , Rick G Schnellmann

Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Sanna H Loppi , Marco A Tavera-Garcia , Danielle A Becktel , Boaz K Maiyo , Kristos E Johnson , Thuy-Vi V Nguyen , Rick G Schnellmann , Kristian P Doyle

Pharmacological Stimulation of Mitochondrial Biogenesis Using the Food and Drug Administration-Approved β

Journal of neurotrauma

Avec: Natalie E Scholpa , Hannah Williams , Wenxue Wang , Daniel Corum , Aarti Narang , Stephen Tomlinson , Patrick G Sullivan , Alexander G Rabchevsky , Rick G Schnellmann

Formoterol PLGA-PEG Nanoparticles Induce Mitochondrial Biogenesis in Renal Proximal Tubules.

The AAPS journal

Avec: Ernest L Vallorz , Karen Blohm-Mangone , Rick G Schnellmann , Heidi M Mansour

Measurement of Cell Death in Mammalian Cells.

Current protocols

Avec: Brian S Cummings , Rick G Schnellmann

Design, Development, Physicochemical Characterization, and In Vitro Drug Release of Formoterol PEGylated PLGA Polymeric Nanoparticles.

Pharmaceutics

Avec: Ernest L Vallorz , David Encinas-Basurto , Rick G Schnellmann , Heidi M Mansour

Increased Renal Expression of Complement Components in Patients With Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Kayla L Frost , Joseph L Jilek , Austin D Thompson , Robert R Klein , Shripad Sinari , Elmira Torabzedehkorasani , Dean D Billheimer , Rick G Schnellmann , Nathan J Cherrington

The β

Biochemical pharmacology

Avec: Kristan H Cleveland , Rick G Schnellmann

Serotonin regulation of mitochondria in kidney diseases.

Pharmacological research

Avec: Kevin Hurtado , Natalie E Scholpa , Jennifer G Schnellmann , Rick G Schnellmann

The Journal of pharmacology and experimental therapeutics

Avec: Ingrid L Peterson , Natalie E Scholpa , Kiara J Bachtle , Jennifer B Frye , Sanna H Loppi , Austin D Thompson , Kristian Doyle , Tally Marie Largent-Milnes , Rick G Schnellmann

Elucidation of cGMP-dependent induction of mitochondrial biogenesis through PKG and p38 MAPK in the kidney.

American journal of physiology. Renal physiology

Avec: Pallavi Bhargava , Jaroslav Janda , Rick G Schnellmann

PDE5 inhibition rescues mitochondrial dysfunction and angiogenic responses induced by Akt3 inhibition by promotion of PRC expression.

The Journal of biological chemistry

Avec: Daniel G Corum , Dorea P Jenkins , James A Heslop , Lacey M Tallent , Gyda C Beeson , Jeremy L Barth , Rick G Schnellmann , Robin C Muise-Helmericks

Regulation of mitochondrial dynamics and energetics in the diabetic renal proximal tubule by the β

American journal of physiology. Renal physiology

Avec: Kristan H Cleveland , Frank C Brosius , Rick G Schnellmann

FDA-approved 5-HT

Experimental neurology

Avec: Epiphani C Simmons , Natalie E Scholpa , Rick G Schnellmann

Pharmacological Targeting of Mitochondria in Diabetic Kidney Disease.

Pharmacological reviews

Avec: Kristan H Cleveland , Rick G Schnellmann

Discovering Novel Plasma Biomarkers for Ischemic Stroke: Lipidomic and Metabolomic Analyses in an Aged Mouse Model.

Journal of lipid research

Avec: Danielle A Becktel , Jennifer B Frye , Elizabeth H Le , Susan A Whitman , Rick G Schnellmann , Helena W Morrison , Kristian P Doyle

Extracellular signal-regulated kinase 1/2 regulates NAD metabolism during acute kidney injury through microRNA-34a-mediated NAMPT expression.

Cellular and molecular life sciences : CMLS

Avec: Justin B Collier , Rick G Schnellmann

β

Experimental neurology

Avec: Natalie E Scholpa , Epiphani C Simmons , Douglas G Tilley , Rick G Schnellmann

Post-Stroke Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Attenuates Chronic Changes in Brain Metabolism, Increases Neurotransmitter Levels, and Improves Recovery.

The Journal of pharmacology and experimental therapeutics

Avec: Thuy-Vi V Nguyen , Rachel H Crumpacker , Kylie E Calderon , Frankie G Garcia , Jacob C Zbesko , Jennifer B Frye , Selena Gonzalez , Danielle A Becktel , Tao Yang , Marco A Tavera-Garcia , Helena W Morrison , Rick G Schnellmann , Frank M Longo , Kristian P Doyle

Kidney targeting of formoterol containing polymeric nanoparticles improves recovery from ischemia reperfusion-induced acute kidney injury in mice.

Kidney international

Avec: Ernest L Vallorz , Jaroslav Janda , Heidi M Mansour , Rick G Schnellmann

Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma.

bioRxiv : the preprint server for biology

Avec: Jiawen Yang , James T Lim , Paul Victor , Chen Chen , Hunain Khwaja , Rick G Schnellmann , Denise J Roe , Prafulla C Gokhale , James A DeCaprio , Megha Padi

Boosting Mitochondrial Biogenesis Diminishes Foam Cell Formation in the Post-Stroke Brain.

International journal of molecular sciences

Avec: Sanna H Loppi , Marco A Tavera-Garcia , Natalie E Scholpa , Boaz K Maiyo , Danielle A Becktel , Helena W Morrison , Rick G Schnellmann , Kristian P Doyle

A refined protocol for the isolation and monoculture of primary mouse renal peritubular endothelial cells.

Frontiers in cardiovascular medicine

Avec: Austin D Thompson , Jaroslav Janda , Rick G Schnellmann

5-HT

Frontiers in cellular neuroscience

Avec: Natalie E Scholpa , Epiphani C Simmons , Austin D Thompson , Seth S Carroll , Rick G Schnellmann

Time-to-treatment window and cross-sex potential of β

Toxicology and applied pharmacology

Avec: Natalie E Scholpa , Epiphani C Simmons , Josh D Crossman , Rick G Schnellmann

Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury.

Kidney international

Avec: Ehtesham Arif , Ashish K Solanki , Pankaj Srivastava , Bushra Rahman , Wayne R Fitzgibbon , Peifeng Deng , Milos N Budisavljevic , Catalin F Baicu , Michael R Zile , Judit Megyesi , Michael G Janech , Sang-Ho Kwon , Justin Collier , Rick G Schnellmann , Deepak Nihalani

The 5-hydroxytryptamine receptor 1F stimulates mitochondrial biogenesis and angiogenesis in endothelial cells.

Biochemical pharmacology

Avec: Tess V Dupre , Dorea P Jenkins , Robin C Muise-Helmericks , Rick G Schnellmann

Proximal Tubule

The Journal of pharmacology and experimental therapeutics

Avec: Robert B Cameron , Whitney S Gibbs , Siennah R Miller , Tess V Dupre , Judit Megyesi , Craig C Beeson , Rick G Schnellmann

Author Correction: Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol.

Scientific reports

Avec: Robert B Cameron , Yuri K Peterson , Craig C Beeson , Rick G Schnellmann

Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases.

Experimental neurology

Avec: Epiphani C Simmons , Natalie E Scholpa , Rick G Schnellmann

Formoterol, a β

Neurobiology of disease

Avec: Hemendra J Vekaria , W Brad Hubbard , Natalie E Scholpa , Malinda L Spry , Jennifer L Gooch , Sydney J Prince , Rick G Schnellmann , Patrick G Sullivan

Role of the β

Pharmacological reports : PR

Avec: Ehtesham Arif , Ashish K Solanki , Bushra Rahman , Bethany Wolf , Rick G Schnellmann , Deepak Nihalani , Joshua H Lipschutz

Lasmiditan promotes recovery from acute kidney injury through induction of mitochondrial biogenesis.

American journal of physiology. Renal physiology

Avec: Kevin A Hurtado , Jaroslav Janda , Rick G Schnellmann

Lasmiditan restores mitochondrial quality control mechanisms and accelerates renal recovery after ischemia-reperfusion injury.

Biochemical pharmacology

Avec: Kevin A Hurtado , Jaroslav Janda , Rick G Schnellmann

5-Hydroxytryptamine 1F Receptor Agonist Lasmiditan Differentially Regulates Successful Repair and Failed Repair Genes in a Mouse Model of Acute Kidney Injury.

ACS pharmacology & translational science

Avec: Paul Victor Santiago Raj , Natalie E Scholpa , Kevin A Hurtado , Jaroslav Janda , John Hortareas , Rick G Schnellmann

Réseau de co-auteurs

Natalie E Scholpa 13 collaborations

Epiphani C Simmons 6 collaborations

Jaroslav Janda 6 collaborations

Danielle A Becktel 5 collaborations

Kristian P Doyle 5 collaborations

Austin D Thompson 5 collaborations

Kristan H Cleveland 4 collaborations

Jennifer B Frye 4 collaborations

Marco A Tavera-Garcia 4 collaborations

Thuy-Vi V Nguyen 3 collaborations

Sanna H Loppi 3 collaborations

Ernest L Vallorz 3 collaborations

Heidi M Mansour 3 collaborations

Helena W Morrison 3 collaborations

Kevin A Hurtado 3 collaborations

Jacob C Zbesko 2 collaborations

Frankie G Garcia 2 collaborations

Ingrid L Peterson 2 collaborations

Boaz K Maiyo 2 collaborations

Patrick G Sullivan 2 collaborations

Dorea P Jenkins 2 collaborations

Robin C Muise-Helmericks 2 collaborations

Ehtesham Arif 2 collaborations

Ashish K Solanki 2 collaborations

Bushra Rahman 2 collaborations

Judit Megyesi 2 collaborations

Deepak Nihalani 2 collaborations

Tess V Dupre 2 collaborations

Robert B Cameron 2 collaborations

Craig C Beeson 2 collaborations

Amanda G Chung 1 collaboration

Megan Hayes 1 collaboration

Kylie Calderon 1 collaboration

Jeffrey W Grover 1 collaboration

Anna Li 1 collaboration

Hsin-Jung Joyce Wu 1 collaboration

Tally Largent-Milnes 1 collaboration

Kristos E Johnson 1 collaboration

Hannah Williams 1 collaboration

Wenxue Wang 1 collaboration

Daniel Corum 1 collaboration

Aarti Narang 1 collaboration

Stephen Tomlinson 1 collaboration

Alexander G Rabchevsky 1 collaboration

Karen Blohm-Mangone 1 collaboration

Brian S Cummings 1 collaboration

David Encinas-Basurto 1 collaboration

Kayla L Frost 1 collaboration

Joseph L Jilek 1 collaboration

Robert R Klein 1 collaboration

Shripad Sinari 1 collaboration

Elmira Torabzedehkorasani 1 collaboration

Dean D Billheimer 1 collaboration

Nathan J Cherrington 1 collaboration

Kevin Hurtado 1 collaboration

Jennifer G Schnellmann 1 collaboration

Kiara J Bachtle 1 collaboration

Kristian Doyle 1 collaboration

Tally Marie Largent-Milnes 1 collaboration

Pallavi Bhargava 1 collaboration

Daniel G Corum 1 collaboration

James A Heslop 1 collaboration

Lacey M Tallent 1 collaboration

Gyda C Beeson 1 collaboration

Jeremy L Barth 1 collaboration

Frank C Brosius 1 collaboration

Elizabeth H Le 1 collaboration

Susan A Whitman 1 collaboration

Justin B Collier 1 collaboration

Douglas G Tilley 1 collaboration

Rachel H Crumpacker 1 collaboration

Kylie E Calderon 1 collaboration

Selena Gonzalez 1 collaboration

Tao Yang 1 collaboration

Frank M Longo 1 collaboration

Jiawen Yang 1 collaboration

James T Lim 1 collaboration

Paul Victor 1 collaboration

Chen Chen 1 collaboration

Hunain Khwaja 1 collaboration

Denise J Roe 1 collaboration

Prafulla C Gokhale 1 collaboration

James A DeCaprio 1 collaboration

Megha Padi 1 collaboration

Seth S Carroll 1 collaboration

Josh D Crossman 1 collaboration

Pankaj Srivastava 1 collaboration

Wayne R Fitzgibbon 1 collaboration

Peifeng Deng 1 collaboration

Milos N Budisavljevic 1 collaboration

Catalin F Baicu 1 collaboration

Michael R Zile 1 collaboration

Michael G Janech 1 collaboration

Sang-Ho Kwon 1 collaboration

Justin Collier 1 collaboration

Whitney S Gibbs 1 collaboration

Siennah R Miller 1 collaboration

Yuri K Peterson 1 collaboration

Hemendra J Vekaria 1 collaboration

W Brad Hubbard 1 collaboration

Malinda L Spry 1 collaboration

Jennifer L Gooch 1 collaboration

Sydney J Prince 1 collaboration

Bethany Wolf 1 collaboration

Joshua H Lipschutz 1 collaboration

Paul Victor Santiago Raj 1 collaboration

John Hortareas 1 collaboration