Excessive Daytime Sleepiness in Major Dementia Syndromes.
Alzheimer’s disease
dementia with Lewy bodies
excessive daytime sleepiness
frontotemporal dementia
Journal
American journal of Alzheimer's disease and other dementias
ISSN: 1938-2731
Titre abrégé: Am J Alzheimers Dis Other Demen
Pays: United States
ID NLM: 101082834
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
pubmed:
12
2
2019
medline:
22
4
2020
entrez:
12
2
2019
Statut:
ppublish
Résumé
There has been no comparison of excessive daytime sleepiness (EDS) in patients with Alzheimer's disease dementia (AD), dementia with Lewy bodies (DLB), and behavioral variant frontotemporal dementia (bvFTD). We identified patients with mild dementia who met criteria for these disorders who also had the Epworth Sleepiness Scale (ESS) completed. The sample included 17 bvFTD, 111 AD, and 31 DLB. An ESS score ≥10 was considered abnormal and consistent with EDS. Analyses with age and sex as covariates revealed higher mean ESS scores for DLB compared to the other groups (DLB 13.9 [5], bvFTD 9.6 [8], AD 8.8 [5], P < .05). An ESS score ≥10 was significantly more likely to occur in DLB compared to bvFTD or AD (DLB 81% vs bvFTD 47% vs AD 45%, P < .01). In patients with mild dementia, EDS is greatest in DLB and comparably lower in bvFTD and AD.
Identifiants
pubmed: 30740984
doi: 10.1177/1533317519828046
pmc: PMC6709580
mid: NIHMS1044752
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
261-264Subventions
Organisme : NIA NIH HHS
ID : P50 AG016574
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG015866
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG057708
Pays : United States
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