Biochemical characterization of TyrA dehydrogenases from Saccharomyces cerevisiae (Ascomycota) and Pleurotus ostreatus (Basidiomycota).
Arogenate dehydrogenase
Fungi metabolic pathway
Prephenate dehydrogenase
Tyrosine biosynthesis
Journal
Archives of biochemistry and biophysics
ISSN: 1096-0384
Titre abrégé: Arch Biochem Biophys
Pays: United States
ID NLM: 0372430
Informations de publication
Date de publication:
15 04 2019
15 04 2019
Historique:
received:
22
11
2018
revised:
06
02
2019
accepted:
12
02
2019
pubmed:
17
2
2019
medline:
15
2
2020
entrez:
17
2
2019
Statut:
ppublish
Résumé
L-Tyrosine is an aromatic amino acid necessary for protein synthesis in all living organisms and a precursor of secondary (specialized) metabolites. In fungi, tyrosine-derived compounds are associated with virulence and defense (i.e. melanin production). However, how tyrosine is produced in fungi is not fully understood. Generally, tyrosine can be synthesized via two pathways: by prephenate dehydrogenase (TyrA
Identifiants
pubmed: 30771296
pii: S0003-9861(18)30931-7
doi: 10.1016/j.abb.2019.02.005
pii:
doi:
Substances chimiques
Fungal Proteins
0
NAD
0U46U6E8UK
Tyrosine
42HK56048U
Oxidoreductases
EC 1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
12-19Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.