Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
22 02 2019
22 02 2019
Historique:
received:
30
11
2018
accepted:
18
01
2019
entrez:
24
2
2019
pubmed:
24
2
2019
medline:
12
9
2020
Statut:
epublish
Résumé
Moraxella catarrhalis is a host-adapted bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease. This study characterises the conserved M. catarrhalis extracellular nuclease, a member of the ββα metal finger family of nucleases, that we have named NucM. NucM shares conserved sequence motifs from the ββα nuclease family, including the DRGH catalytic core and Mg
Identifiants
pubmed: 30796312
doi: 10.1038/s41598-019-39374-0
pii: 10.1038/s41598-019-39374-0
pmc: PMC6384898
doi:
Substances chimiques
Bacterial Proteins
0
DNA, Bacterial
0
RNA, Bacterial
0
Deoxyribonucleases
EC 3.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2579Références
J Mol Biol. 1999 May 21;288(5):975-87
pubmed: 10329193
Science. 1999 May 21;284(5418):1318-22
pubmed: 10334980
J Bacteriol. 2000 Nov;182(21):6192-202
pubmed: 11029442
Mol Microbiol. 2001 May;40(3):634-44
pubmed: 11359569
Clin Microbiol Rev. 2002 Jan;15(1):125-44
pubmed: 11781271
Science. 2002 Feb 22;295(5559):1487
pubmed: 11859186
Nat Rev Microbiol. 2004 Mar;2(3):241-9
pubmed: 15083159
Curr Opin Otolaryngol Head Neck Surg. 2004 Jun;12(3):185-90
pubmed: 15167027
Infect Immun. 2004 Nov;72(11):6262-70
pubmed: 15501752
J Bacteriol. 2005 May;187(10):3421-30
pubmed: 15866928
J Biol Chem. 2005 Jul 29;280(30):27990-7
pubmed: 15897201
Infect Immun. 2005 Jun;73(6):3693-701
pubmed: 15908399
Mol Microbiol. 2006 Jan;59(2):376-85
pubmed: 16390436
Curr Biol. 2006 Feb 21;16(4):401-7
pubmed: 16488875
Plasmid. 2006 Sep;56(2):133-7
pubmed: 16757025
FEMS Microbiol Lett. 2006 Sep;262(1):72-6
pubmed: 16907741
J Infect Dis. 2007 Jun 1;195(11):1661-70
pubmed: 17471436
Genome Res. 2007 Nov;17(11):1647-56
pubmed: 17895425
Appl Environ Microbiol. 2008 Feb;74(4):1198-208
pubmed: 18156329
J Bacteriol. 2008 Nov;190(21):7232-40
pubmed: 18757542
Microbes Infect. 2009 Apr;11(5):545-53
pubmed: 19306940
Clin Infect Dis. 2009 Jul 1;49(1):124-31
pubmed: 19480579
J Bacteriol. 2010 Jul;192(14):3574-83
pubmed: 20453089
Bioinformatics. 2010 Jul 1;26(13):1608-15
pubmed: 20472543
Nat Protoc. 2010 Jul;5(7):1236-54
pubmed: 20595953
MBio. 2010 Jul 06;1(3):null
pubmed: 20802829
J Innate Immun. 2010;2(6):576-86
pubmed: 20829609
Nucleic Acids Res. 2011 Jan;39(2):623-34
pubmed: 20846957
Nucleic Acids Res. 2011 Apr;39(7):2943-53
pubmed: 21113026
Mol Microbiol. 2011 Mar;79(6):1629-42
pubmed: 21231972
Infect Immun. 2011 Apr;79(4):1504-11
pubmed: 21300774
Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4494-9
pubmed: 21368196
Antimicrob Agents Chemother. 2011 Aug;55(8):3845-53
pubmed: 21576428
Nat Methods. 2011 Sep 29;8(10):785-6
pubmed: 21959131
Mol Microbiol. 2011 Nov;82(4):1015-37
pubmed: 22032623
PLoS One. 2011;6(11):e26714
pubmed: 22096493
FEMS Microbiol Rev. 2013 May;37(3):336-63
pubmed: 22928673
Nucleic Acids Res. 2013 Jan;41(Database issue):D344-7
pubmed: 23161676
PLoS One. 2013;8(2):e53837
pubmed: 23393551
Antimicrob Agents Chemother. 2013 May;57(5):2352-61
pubmed: 23478967
J Mol Biol. 1990 Jun 20;213(4):727-38
pubmed: 2359120
Lett Appl Microbiol. 2013 Dec;57(6):467-75
pubmed: 23848166
Environ Microbiol. 2013 Nov;15(11):2879-93
pubmed: 23869714
J Infect Dis. 1990 Sep;162(3):685-94
pubmed: 2387994
PLoS Pathog. 2013;9(9):e1003596
pubmed: 24039578
PLoS Pathog. 2013;9(9):e1003614
pubmed: 24039581
Crit Rev Microbiol. 2015;41(3):341-52
pubmed: 24303798
Pathog Dis. 2014 Apr;70(3):280-8
pubmed: 24391058
J Bacteriol. 2014 Apr;196(8):1471-83
pubmed: 24488316
Nat Rev Microbiol. 2014 Mar;12(3):181-96
pubmed: 24509783
PLoS One. 2014 Aug 01;9(8):e103125
pubmed: 25084357
FASEB J. 2014 Dec;28(12):5197-207
pubmed: 25183669
Curr Opin Biotechnol. 2015 Jun;33:73-80
pubmed: 25528382
Infect Immun. 2015 Mar;83(3):950-7
pubmed: 25547799
J Infect Dis. 2015 Jul 15;212(2):316-24
pubmed: 25605868
Nat Protoc. 2015 Jun;10(6):845-58
pubmed: 25950237
Mol Microbiol. 2015 Sep;97(5):881-97
pubmed: 26036301
Nucleic Acids Res. 2016 Jan 4;44(D1):D279-85
pubmed: 26673716
Sci Rep. 2016 Jan 08;6:19033
pubmed: 26742696
PLoS One. 2016 Mar 08;11(3):e0150949
pubmed: 26953891
Mol Biol Evol. 2016 Jul;33(7):1870-4
pubmed: 27004904
PLoS Pathog. 2016 Jun 23;12(6):e1005686
pubmed: 27336156
Nat Rev Dis Primers. 2016 Sep 08;2:16063
pubmed: 27604644
Philos Trans R Soc Lond B Biol Sci. 2016 Oct 19;371(1706):
pubmed: 27619692
Vaccine. 2017 Feb 6;:
pubmed: 28185742
Microbiology. 2017 Oct;163(10):1371-1384
pubmed: 28893369
Nat Rev Microbiol. 2018 Jul;16(7):397-409
pubmed: 29720707
Genome Biol Evol. 2018 Nov 1;10(11):2932-2946
pubmed: 30335144
Drugs. 1986;31 Suppl 3:55-63
pubmed: 3488198
Appl Environ Microbiol. 1986 Sep;52(3):546-51
pubmed: 3767360
Proc Natl Acad Sci U S A. 1974 Jun;71(6):2305-9
pubmed: 4152205
J Bacteriol. 1984 Mar;157(3):733-8
pubmed: 6421799
Am J Otol. 1993 Nov;14(6):601-4
pubmed: 7507647
Mol Microbiol. 1995 Jan;15(2):213-23
pubmed: 7746143
Nucleic Acids Res. 1996 Jul 15;24(14):2632-9
pubmed: 8758988
Microb Pathog. 1995 Dec;19(6):391-407
pubmed: 8852280
Nucleic Acids Res. 1997 Sep 1;25(17):3389-402
pubmed: 9254694