Reply to Comment on 'Linear energy transfer incorporated intensity modulated proton therapy optimization'.


Journal

Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220

Informations de publication

Date de publication:
27 02 2019
Historique:
entrez: 28 2 2019
pubmed: 28 2 2019
medline: 9 11 2019
Statut: epublish

Résumé

In this reply we present additional description of our linear model for LET optimization in response to the comments by Dr Gorissen. We clarify that this model cannot guarantee global optimal solutions to the sum-of-fractions problem. Based on our data, it could be used to optimize LET efficiently while dose constraints are maintained.

Identifiants

pubmed: 30811349
doi: 10.1088/1361-6560/aaff72
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

058002

Commentaires et corrections

Type : CommentOn
Type : CommentOn

Auteurs

Wenhua Cao (W)

Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America. Author to whom any correspondence should be addressed.

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Classifications MeSH