Ferulic Acid Esters and Withanolides: In Search of Withania somnifera GABA
Animals
Coumaric Acids
/ chemical synthesis
Esters
/ chemical synthesis
GABA Modulators
/ chemical synthesis
In Vitro Techniques
Inhibitory Postsynaptic Potentials
/ drug effects
Magnetic Resonance Spectroscopy
Male
Molecular Structure
Plant Extracts
/ chemistry
Plant Roots
/ chemistry
Rats
Rats, Sprague-Dawley
Receptors, GABA-A
/ drug effects
Withania
/ chemistry
Withanolides
/ chemical synthesis
Xenopus
Journal
Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882
Informations de publication
Date de publication:
24 05 2019
24 05 2019
Historique:
pubmed:
19
4
2019
medline:
29
8
2020
entrez:
19
4
2019
Statut:
ppublish
Résumé
Nine compounds, including two undescribed withanolides, withasomniferolides A and B (1 and 2), three known withanolides (3-5), a ferulic acid dimeric ester (6), and an inseparable mixture of three long alkyl chain ferulic acid esters (7-9), were isolated from a GABA
Identifiants
pubmed: 30998355
doi: 10.1021/acs.jnatprod.8b01023
doi:
Substances chimiques
Coumaric Acids
0
Esters
0
GABA Modulators
0
Plant Extracts
0
Receptors, GABA-A
0
Withanolides
0
ferulic acid
AVM951ZWST
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM