Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.

Aged Antigens, Neoplasm / genetics Calreticulin / genetics Female Humans Immunotherapy / methods Male Middle Aged Mutation Myeloproliferative Disorders / genetics Receptors, Thrombopoietin / genetics Sequence Analysis, RNA / methods Transcriptome

Journal

Blood

ISSN: 1528-0020

Titre abrégé: Blood

Pays: United States

ID NLM: 7603509

Informations de publication

Date de publication:
11 07 2019

Historique:

received: 29 10 2018

accepted: 19 04 2019

pubmed: 9 5 2019

medline: 4 1 2020

entrez: 9 5 2019

Statut: ppublish

Résumé

Ph-negative myeloproliferative neoplasms (MPNs) are hematological cancers that can be subdivided into entities with distinct clinical features. Somatic mutations in

Identifiants

DOI: 10.1182/blood.2019000519 PMID: 31064751 PMC: PMC6624966

pubmed: 31064751

pii: S0006-4971(20)42424-3

doi: 10.1182/blood.2019000519

pmc: PMC6624966

doi:

Substances chimiques

Antigens, Neoplasm 0

CALR protein, human 0

Calreticulin 0

Receptors, Thrombopoietin 0

MPL protein, human 143641-95-6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

199-210

Subventions

Organisme : Austrian Science Fund FWF

ID : P 29018

Pays : Austria

Commentaires et corrections

Type : CommentIn

Informations de copyright

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