Homozygosity for


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
21 05 2019
Historique:
pubmed: 10 5 2019
medline: 27 3 2020
entrez: 10 5 2019
Statut: ppublish

Résumé

The human genetic basis of tuberculosis (TB) has long remained elusive. We recently reported a high level of enrichment in homozygosity for the common

Identifiants

pubmed: 31068474
pii: 1903561116
doi: 10.1073/pnas.1903561116
pmc: PMC6534977
doi:

Substances chimiques

TYK2 Kinase EC 2.7.10.2
TYK2 protein, human EC 2.7.10.2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10430-10434

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR001866
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI089970
Pays : United States
Organisme : NIAID NIH HHS
ID : R37 AI095983
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI088685
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI111143
Pays : United States

Déclaration de conflit d'intérêts

Conflict of interest statement: J.-L.C. and M.L. are coauthors on a 2019 paper [Ahmad L (2019) J Allergy Clin Immunol 143:765–769] and a 2017 paper [Israel L (2017) Cell 168:789–800] in which they independently provided unpublished reagents/analytic tools. J.-L.C., L.A., and D.K. are coauthors on a 2018 paper [Bolze A (2018) Proc Natl Acad Sci USA 115:E8007–E8016] in which they independently provided unpublished reagents/analytic tools.

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Auteurs

Gaspard Kerner (G)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France.
Imagine Institute, Paris Descartes University, 75015 Paris, France.

Noe Ramirez-Alejo (N)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.

Yoann Seeleuthner (Y)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France.
Imagine Institute, Paris Descartes University, 75015 Paris, France.

Rui Yang (R)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.

Masato Ogishi (M)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.

Aurélie Cobat (A)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France.
Imagine Institute, Paris Descartes University, 75015 Paris, France.

Etienne Patin (E)

Human Evolutionary Genetics Unit, Institut Pasteur, CNRS UMR2000, 75015 Paris, France.

Lluis Quintana-Murci (L)

Human Evolutionary Genetics Unit, Institut Pasteur, CNRS UMR2000, 75015 Paris, France.

Stéphanie Boisson-Dupuis (S)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France.
Imagine Institute, Paris Descartes University, 75015 Paris, France.
St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.

Jean-Laurent Casanova (JL)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France; casanova@rockefeller.edu.
Imagine Institute, Paris Descartes University, 75015 Paris, France.
St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.
Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris, 75015 Paris, France.
Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065.

Laurent Abel (L)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR 1163, Necker Hospital for Sick Children, 75015 Paris, France.
Imagine Institute, Paris Descartes University, 75015 Paris, France.
St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065.

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