Phosphatase 1 Nuclear Targeting Subunit, a Novel DNA Repair Partner of PARP1.

DNA Damage / drug effects DNA Repair / drug effects Phosphoric Monoester Hydrolases / genetics Poly (ADP-Ribose) Polymerase-1 / genetics Poly(ADP-ribose) Polymerase Inhibitors

Journal

Cancer research
ISSN: 1538-7445
Titre abrégé: Cancer Res
Pays: United States
ID NLM: 2984705R

Informations de publication

Date de publication:
15 05 2019
Historique:
received: 08 03 2019
accepted: 12 03 2019
entrez: 17 5 2019
pubmed: 17 5 2019
medline: 4 7 2019
Statut: ppublish

Résumé

There is extensive literature on PARP1, owing to the multiple functions of PARP1 for DNA repair, aging, chromatin remodeling and transcription, and to the successful clinical development of four PARP inhibitors. In this issue of

Identifiants

DOI: 10.1158/0008-5472.CAN-19-0798 PMID: 31092408
pubmed: 31092408
pii: 79/10/2460
doi: 10.1158/0008-5472.CAN-19-0798
doi:

Substances chimiques

Poly(ADP-ribose) Polymerase Inhibitors 0
Poly (ADP-Ribose) Polymerase-1 EC 2.4.2.30
Phosphoric Monoester Hydrolases EC 3.1.3.2

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

2460-2461

Commentaires et corrections

Type : CommentOn

Informations de copyright

©2019 American Association for Cancer Research.

Auteurs

Junko Murai (J)

Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata, Japan. pommier@nih.gov muraij@ttck.keio.ac.jp.

Yves Pommier (Y)

Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. pommier@nih.gov muraij@ttck.keio.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Altération de l'ADN › Phosphatase 1 Nuclear Targeting Subunit, a...
questionsmedicales.fr › Phénomènes génétiques › Réparation de l'ADN › Phosphatase 1 Nuclear Targeting Subunit, a...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Phosphoric monoester hydrolases › Phosphatase 1 Nuclear Targeting Subunit, a...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Glycosyltransferase › Pentosyltransferases › ADP ribose transferases › Poly(ADP-ribose) polymerases › Poly (ADP-Ribose) polymerase-1 › Phosphatase 1 Nuclear Targeting Subunit, a...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Inhibiteurs de poly(ADP-ribose) polymérases › Phosphatase 1 Nuclear Targeting Subunit, a...