Basidiobolus haptosporus-like fungus as a causal agent of gastrointestinal basidiobolomycosis.
Entomophthoromycota
Aseer region
Basidiobolomycosis
LSU rRNA gene
zygomycetes
Journal
Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835
Informations de publication
Date de publication:
01 Feb 2020
01 Feb 2020
Historique:
received:
12
03
2019
revised:
03
04
2019
accepted:
14
04
2019
pubmed:
22
5
2019
medline:
15
9
2020
entrez:
22
5
2019
Statut:
ppublish
Résumé
Basidiobolus species were isolated from colonic biopsy samples of patients with gastrointestinal basidiobolomycosis (GIB) in southern Saudi Arabia. Isolated fungi were initially identified using classical mycological tools and confirmed by sequence analysis of the large subunit ribosomal RNA gene. Phenotypic tests revealed zygomycete-like fungi which conform to those of Basidiobolus species. Five sequenced strains formed a monophyletic clade in the 28S ribosomal RNA gene phylogenetic tree. They shared 99.97% similarity with B. haptosporus and 99.97% with B. haptosporus var. minor, and relatively lower similarity with B. ranarum (99.925%). The study suggests a new and a serious causal agent of GIB related to Basidiobolus haptosporus. These isolates are not related to B. ranarum, which is commonly linked to this disease.
Identifiants
pubmed: 31111900
pii: 5492539
doi: 10.1093/mmy/myz046
doi:
Substances chimiques
RNA, Ribosomal, 28S
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
264-267Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.