The Cross-Talk between miR-511-3p and C-Type Lectin Receptors on Dendritic Cells Affects Dendritic Cell Function.
Cell Differentiation
Cells, Cultured
Coculture Techniques
Dendritic Cells
/ physiology
Gene Expression Regulation
Humans
Immunomodulation
Indoleamine-Pyrrole 2,3,-Dioxygenase
/ metabolism
Intercellular Adhesion Molecule-3
/ genetics
Interleukin-10
/ metabolism
Interleukin-4
/ metabolism
Lectins, C-Type
/ metabolism
Lymphocyte Activation
MicroRNAs
/ genetics
RNA, Small Interfering
/ genetics
Receptor Cross-Talk
T-Lymphocytes, Helper-Inducer
/ immunology
Journal
Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R
Informations de publication
Date de publication:
01 07 2019
01 07 2019
Historique:
received:
10
08
2018
accepted:
29
04
2019
pubmed:
24
5
2019
medline:
3
3
2020
entrez:
24
5
2019
Statut:
ppublish
Résumé
MicroRNAs are small, noncoding RNAs that function as posttranscriptional modulators of gene expression by binding target mRNAs and inhibiting translation. They are therefore crucial regulators of several biological as well as immunological events. Recently, miR-511-3p has been implicated in the development and differentiation of APCs, such as dendritic cells (DCs), and regulating several human diseases. Interestingly, miR-511-3p is embedded within the human
Identifiants
pubmed: 31118225
pii: jimmunol.1801108
doi: 10.4049/jimmunol.1801108
doi:
Substances chimiques
Indoleamine-Pyrrole 2,3,-Dioxygenase
0
Intercellular Adhesion Molecule-3
0
Lectins, C-Type
0
MIRN511 microRNA, human
0
MicroRNAs
0
RNA, Small Interfering
0
Interleukin-10
130068-27-8
Interleukin-4
207137-56-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
148-157Informations de copyright
Copyright © 2019 by The American Association of Immunologists, Inc.