Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters.

Bacillus / genetics Genes, Reporter / genetics Iron / chemistry Microscopy, Electron Myxococcus xanthus / genetics Nanocomposites / chemistry Particle Size Surface Properties
compartmentalization cryo-electron microscopy electron microscopy encapsulin gene reporter iron biomineralization multiplexing

Journal

ACS nano
ISSN: 1936-086X
Titre abrégé: ACS Nano
Pays: United States
ID NLM: 101313589

Informations de publication

Date de publication:
23 07 2019
Historique:
pubmed: 14 6 2019
medline: 22 8 2020
entrez: 14 6 2019
Statut: ppublish

Résumé

Multicolored gene reporters for light microscopy are indispensable for biomedical research, but equivalent genetic tools for electron microscopy (EM) are still rare despite the increasing importance of nanometer resolution for reverse engineering of molecular machinery and reliable mapping of cellular circuits. We here introduce the fully genetic encapsulin/cargo system of

Identifiants

DOI: 10.1021/acsnano.9b03140 PMID: 31194509
pubmed: 31194509
doi: 10.1021/acsnano.9b03140
doi:

Substances chimiques

Iron E1UOL152H7

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8114-8123

Auteurs

Felix Sigmund (F)

Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.
Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.

Susanne Pettinger (S)

Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.
Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.

Massimo Kube (M)

Laboratory for Biomolecular Design, Department of Physics , Technical University of Munich , 85748 Garching , Germany.

Fabian Schneider (F)

Laboratory for Biomolecular Design, Department of Physics , Technical University of Munich , 85748 Garching , Germany.

Martina Schifferer (M)

Institute of Neuronal Cell Biology, TUM School of Medicine , Technical University of Munich , 80802 Munich , Germany.
German Center for Neurodegenerative Diseases (DZNE) , 81377 Munich , Germany.

Steffen Schneider (S)

Computational Neuroengineering, Department of Electrical and Computer Engineering , Technical University of Munich , 80333 Munich , Germany.
Tübingen AI Center , University of Tübingen , 72076 Tübingen , Germany.

Maria V Efremova (MV)

Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.
Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
Laboratory of Chemical Design of Bionanomaterials for Medical Applications, Department of Chemistry , Lomonosov Moscow State University , 119991 Moscow , Russian Federation.
ORCID: 0000-0002-5196-5596

Jesús Pujol-Martí (J)

Department "Circuits - Computation - Models" , Max Planck Institute of Neurobiology , 82152 Martinsried , Germany.

Michaela Aichler (M)

Research Unit Analytical Pathology , Helmholtz Zentrum München , 85764 Neuherberg , Germany.

Axel Walch (A)

Research Unit Analytical Pathology , Helmholtz Zentrum München , 85764 Neuherberg , Germany.

Thomas Misgeld (T)

Institute of Neuronal Cell Biology, TUM School of Medicine , Technical University of Munich , 80802 Munich , Germany.
German Center for Neurodegenerative Diseases (DZNE) , 81377 Munich , Germany.

Hendrik Dietz (H)

Laboratory for Biomolecular Design, Department of Physics , Technical University of Munich , 85748 Garching , Germany.

Gil G Westmeyer (GG)

Department of Nuclear Medicine, TUM School of Medicine , Technical University of Munich , 81675 Munich , Germany.
Institute of Biological and Medical Imaging , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
Institute of Developmental Genetics , Helmholtz Zentrum München , 85764 Neuherberg , Germany.
ORCID: 0000-0001-7224-8919

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Classifications MeSH

questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets sporulés à Gram positif › Bacillaceae › Bacillus › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes rapporteurs › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Fer › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Bactéries › Proteobacteria › Deltaproteobacteria › Myxococcales › Myxococcus › Myxococcus xanthus › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanocomposites › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Phénomènes chimiques › Taille de particule › Iron-Sequestering Nanocompartments as...
questionsmedicales.fr › Phénomènes chimiques › Propriétés de surface › Iron-Sequestering Nanocompartments as...