WRINKLED1 Regulates BIOTIN ATTACHMENT DOMAIN-CONTAINING Proteins that Inhibit Fatty Acid Synthesis.


Journal

Plant physiology
ISSN: 1532-2548
Titre abrégé: Plant Physiol
Pays: United States
ID NLM: 0401224

Informations de publication

Date de publication:
09 2019
Historique:
received: 14 05 2019
accepted: 07 06 2019
pubmed: 19 6 2019
medline: 1 9 2020
entrez: 19 6 2019
Statut: ppublish

Résumé

WRINKLED1 (WRI1) is a transcriptional activator that binds to a conserved sequence (designated as AW box) boxes in the promoters of many genes from central metabolism and fatty acid (FA) synthesis, resulting in their transcription. BIOTIN ATTACHMENT DOMAIN-CONTAINING (BADC) proteins lack a biotin-attachment domain and are therefore inactive, but in the presence of excess FA, BADC1 and BADC3 are primarily responsible for the observed long-term irreversible inhibition of ACETYL-COA CARBOXYLASE, and consequently FA synthesis. Here, we tested the interaction of WRI1 with

Identifiants

pubmed: 31209126
pii: pp.19.00587
doi: 10.1104/pp.19.00587
pmc: PMC6716254
doi:

Substances chimiques

Arabidopsis Proteins 0
Fatty Acids 0
Transcription Factors 0
WRINKLED1 protein, Arabidopsis 0
Biotin 6SO6U10H04
Acetyl-CoA Carboxylase EC 6.4.1.2

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

55-62

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2019 American Society of Plant Biologists. All Rights Reserved.

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Auteurs

Hui Liu (H)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973.

Zhiyang Zhai (Z)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973.

Kate Kuczynski (K)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973.

Jantana Keereetaweep (J)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973.

Jorg Schwender (J)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973.

John Shanklin (J)

Department of Biology, Brookhaven National Laboratory 463, Upton, New York 11973 shanklin@bnl.gov.

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Classifications MeSH