Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation.


Journal

Global heart
ISSN: 2211-8179
Titre abrégé: Glob Heart
Pays: England
ID NLM: 101584391

Informations de publication

Date de publication:
06 2019
Historique:
received: 27 05 2019
accepted: 03 06 2019
entrez: 21 7 2019
pubmed: 22 7 2019
medline: 29 1 2020
Statut: ppublish

Résumé

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based interventions for control of HTN in high-income countries exist, implementation of these in low- and middle-income countries has been challenging due to limited capacity and infrastructure for late-phase translational research. In Rwanda, the 2015 STEPS NCD (STEPwise Approach to Surveillance of Noncommunicable Diseases) risk survey reported an overall prevalence of HTN of 15% (95% confidence interval [CI]: 13.8 to 16.3) for those ages 15 to 64 years; prevalence increased with increasing age to 39% (95% CI: 35.7 to 43.1) for those ages 55 to 64 years; CVD was the third most common cause of mortality (7%). Suboptimal infrastructure and capacity in Rwanda hinders research and community knowledge for HTN control. To address the issue of suboptimal capacity to implement evidence-based interventions in HTN, this project was designed with the following objectives: 1) to develop a regional needs assessment of infrastructure for dissemination and implementation (D & I) strategies for HTN-CVD control; 2) to develop HTN-CVD research capacity through creation of countrywide resources such as core research facilities and training in the fields of HTN-CVD, D & I, and biostatistics; and 3) to engage and train multiple stakeholders in D & I and HTN-CVD evidence-based interventions. A weeklong training program in HTN-CVD, biostatistics, and D & I was conducted in Rwanda in August 2018, and pre- and post-D & I training competency questionnaires were administered. Questionnaire results show a statistically significant increase in D & I knowledge and skills as a result of training (full scale pre- to post-test scores: 2.12 ± 0.78 vs. 3.94 ± 0.42; p < 0.0001). Using principles of community engagement and train-the-trainer methods, we will continue to adapt guidelines and treatments for HTN-CVD developed in high-income countries to the context of Rwanda with the goal of establishing a sustainable platform to address the burden of disease from HTN-CVD.

Sections du résumé

BACKGROUND
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based interventions for control of HTN in high-income countries exist, implementation of these in low- and middle-income countries has been challenging due to limited capacity and infrastructure for late-phase translational research. In Rwanda, the 2015 STEPS NCD (STEPwise Approach to Surveillance of Noncommunicable Diseases) risk survey reported an overall prevalence of HTN of 15% (95% confidence interval [CI]: 13.8 to 16.3) for those ages 15 to 64 years; prevalence increased with increasing age to 39% (95% CI: 35.7 to 43.1) for those ages 55 to 64 years; CVD was the third most common cause of mortality (7%). Suboptimal infrastructure and capacity in Rwanda hinders research and community knowledge for HTN control.
OBJECTIVES
To address the issue of suboptimal capacity to implement evidence-based interventions in HTN, this project was designed with the following objectives: 1) to develop a regional needs assessment of infrastructure for dissemination and implementation (D & I) strategies for HTN-CVD control; 2) to develop HTN-CVD research capacity through creation of countrywide resources such as core research facilities and training in the fields of HTN-CVD, D & I, and biostatistics; and 3) to engage and train multiple stakeholders in D & I and HTN-CVD evidence-based interventions.
METHODS
A weeklong training program in HTN-CVD, biostatistics, and D & I was conducted in Rwanda in August 2018, and pre- and post-D & I training competency questionnaires were administered.
RESULTS
Questionnaire results show a statistically significant increase in D & I knowledge and skills as a result of training (full scale pre- to post-test scores: 2.12 ± 0.78 vs. 3.94 ± 0.42; p < 0.0001).
CONCLUSIONS
Using principles of community engagement and train-the-trainer methods, we will continue to adapt guidelines and treatments for HTN-CVD developed in high-income countries to the context of Rwanda with the goal of establishing a sustainable platform to address the burden of disease from HTN-CVD.

Identifiants

pubmed: 31324367
pii: S2211-8160(19)30085-7
doi: 10.1016/j.gheart.2019.06.001
pmc: PMC6816501
mid: NIHMS1055703
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

135-141

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK056341
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI025903
Pays : United States
Organisme : NHLBI NIH HHS
ID : U24 HL136790
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002345
Pays : United States

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

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Auteurs

Ana A Baumann (AA)

Brown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.

Vincent Mutabazi (V)

Regional Alliance for Sustainable Development, Kigali, Rwanda.

Angela L Brown (AL)

Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.

Cole Hooley (C)

Brown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.

Dominic Reeds (D)

Division of Geriatrics and Nutritional Science, Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA.

Cecile Ingabire (C)

School of Nursing and Midwifery, University of Rwanda, Kigali, Rwanda.

Vedaste Ndahindwa (V)

School of Nursing and Midwifery, University of Rwanda, Kigali, Rwanda.

Aurore Nishimwe (A)

School of Health Sciences, University of Rwanda, Kigali, Rwanda.

W Todd Cade (WT)

Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.

Lisa de Las Fuentes (L)

Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA; Divisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.

Enola K Proctor (EK)

Brown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.

Stephen Karengera (S)

Regional Alliance for Sustainable Development, Kigali, Rwanda; EAC RCE-VIHSCM, College of Medicine and Heath Sciences, University of Rwanda, Kigali, Rwanda.

Kenneth B Schecthman (KB)

Divisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.

Charles W Goss (CW)

Divisions of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.

Kevin Yarasheski (K)

C2N Diagnostics, LLC, St. Louis, MO, USA.

Brad Newsome (B)

National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

Eugene Mutimura (E)

Regional Alliance for Sustainable Development, Kigali, Rwanda.

Victor G Davila-Roman (VG)

Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: vdavila@wustl.edu.

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