The structure of the influenza A virus genome.


Journal

Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869

Informations de publication

Date de publication:
11 2019
Historique:
received: 13 02 2019
accepted: 12 06 2019
pubmed: 25 7 2019
medline: 8 2 2020
entrez: 24 7 2019
Statut: ppublish

Résumé

Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA segments contained in separate viral ribonucleoprotein (vRNP) complexes that are packaged together into a single virus particle. The structure of viral RNA is believed to play a role in assembling the different vRNPs into budding virions

Identifiants

pubmed: 31332385
doi: 10.1038/s41564-019-0513-7
pii: 10.1038/s41564-019-0513-7
pmc: PMC7191640
mid: NIHMS1581496
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1781-1789

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M011224/1
Pays : United Kingdom
Organisme : NHGRI NIH HHS
ID : R01 HG008133
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL111527
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM101237
Pays : United States
Organisme : Wellcome Trust
ID : 105399/Z/14/Z
Pays : United Kingdom
Organisme : NIGMS NIH HHS
ID : R01 GM126554
Pays : United States
Organisme : Medical Research Council
ID : MR/R009945/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K000241/1
Pays : United Kingdom

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Auteurs

Bernadeta Dadonaite (B)

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

Brad Gilbertson (B)

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Michael L Knight (ML)

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

Sanja Trifkovic (S)

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Steven Rockman (S)

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Seqirus Ltd, Parkville, Victoria, Australia.

Alain Laederach (A)

Department of Biology, University of North Carolina, Chapel Hill, NC, USA.

Lorena E Brown (LE)

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. lorena@unimelb.edu.au.

Ervin Fodor (E)

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. ervin.fodor@path.ox.ac.uk.

David L V Bauer (DLV)

Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. david.bauer@path.ox.ac.uk.

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Classifications MeSH