Myelin Water Fraction and Intra/Extracellular Water Geometric Mean T
atlas
cervical spinal cord
magnetic resonance imaging
myelin water imaging
white matter
Journal
Journal of neuroimaging : official journal of the American Society of Neuroimaging
ISSN: 1552-6569
Titre abrégé: J Neuroimaging
Pays: United States
ID NLM: 9102705
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
30
05
2019
revised:
19
07
2019
accepted:
23
07
2019
pubmed:
14
8
2019
medline:
15
12
2020
entrez:
14
8
2019
Statut:
ppublish
Résumé
Acquiring and interpreting quantitative myelin-specific MRI data at an individual level is challenging because of technical difficulties and natural myelin variation in the population. To overcome these challenges, we used multiecho T Cervical cord MWI was performed at 3T on 20 healthy individuals (10M/10F, mean age: 36 years) and 3 relapsing remitting multiple sclerosis (RRMS) participants (1M/2F, age: 39/42/37 years). Anatomical data were collected for the purpose of image segmentation and registration. Atlases were created by coregistering and averaging T The average MWF atlas provides a representation of myelin in the spinal cord consistent with well-known spinal cord anatomical characteristics. The IEGMT Our findings highlight the potential for using a quantitative T
Sections du résumé
BACKGROUND AND PURPOSE
Acquiring and interpreting quantitative myelin-specific MRI data at an individual level is challenging because of technical difficulties and natural myelin variation in the population. To overcome these challenges, we used multiecho T
METHODS
Cervical cord MWI was performed at 3T on 20 healthy individuals (10M/10F, mean age: 36 years) and 3 relapsing remitting multiple sclerosis (RRMS) participants (1M/2F, age: 39/42/37 years). Anatomical data were collected for the purpose of image segmentation and registration. Atlases were created by coregistering and averaging T
RESULTS
The average MWF atlas provides a representation of myelin in the spinal cord consistent with well-known spinal cord anatomical characteristics. The IEGMT
CONCLUSIONS
Our findings highlight the potential for using a quantitative T
Substances chimiques
Water
059QF0KO0R
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
50-57Subventions
Organisme : CIHR
Pays : Canada
Informations de copyright
© 2019 by the American Society of Neuroimaging.
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