Outcome after type A aortic dissection repair in patients with preoperative cardiac arrest.


Journal

Resuscitation
ISSN: 1873-1570
Titre abrégé: Resuscitation
Pays: Ireland
ID NLM: 0332173

Informations de publication

Date de publication:
11 2019
Historique:
received: 02 03 2019
revised: 11 08 2019
accepted: 25 08 2019
pubmed: 11 9 2019
medline: 2 10 2020
entrez: 11 9 2019
Statut: ppublish

Résumé

Patients presenting with acute type A aortic dissection (ATAAD) and cardiac arrest before surgery are considered to have very poor prognosis, but limited data is available. We used a large database to evaluate the outcome of ATAAD patients with a cardiac arrest before surgery. We evaluated 1154 surgically treated ATAAD patients from the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) database between 2005 and 2014. Patients with (n = 44, 3.8%) and without preoperative cardiac arrest were compared and variables univariably associated with mortality in the cardiac arrest group were identified. Median follow-up time was 2.7 years (interquartile range 0.5-5.5). Thirty-day mortality in the arrest and non-arrest group was 43.2% and 16.6%, respectively (odds ratio [OR] 3.83, CI 2.06-7.09; P < 0.001). In the nine patients with ongoing cardiopulmonary resuscitation when cardiopulmonary bypass was initiated, five died intraoperatively and one died after 65 days. In patients surviving the operation, stroke was significantly more common in the arrest group (48.4% vs 18.2%; OR 4.21, CI 2.05-8.67; P < 0.001). In total, 50.0% (22/44) of the arrest patients survived to the end of follow-up. Non-survivors in the arrest group more often had DeBakey type I dissection, cardiac tamponade, cardiac malperfusion and higher preoperative serum lactate (all P < 0.05). Early mortality and complications after ATAAD surgery in patients with a preoperative cardiac arrest are high, but mid-term outcome after surviving the initial period is acceptable. Preoperative cardiac arrest should not be considered an absolute contraindication for a surgical ATAAD repair.

Identifiants

pubmed: 31505231
pii: S0300-9572(19)30604-5
doi: 10.1016/j.resuscitation.2019.08.039
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-5

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Emily Pan (E)

Department of Cardiothoracic Surgery, Heart Center, Turku University Hospital, Turku, Finland; Department of Surgery and Clinical Medicine, University of Turku, Turku, Finland. Electronic address: xiapan@utu.fi.

Andreas Wallinder (A)

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Eric Peterström (E)

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

Arnar Geirsson (A)

Department of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland; Section of Cardiac Surgery, Yale University School of Medicine, New Haven, CT, USA.

Christian Olsson (C)

Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden.

Anders Ahlsson (A)

Department of Heart and Vascular Theme, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.

Simon Fuglsang (S)

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark.

Jarmo Gunn (J)

Department of Cardiothoracic Surgery, Heart Center, Turku University Hospital, Turku, Finland; Department of Surgery and Clinical Medicine, University of Turku, Turku, Finland.

Emma C Hansson (EC)

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Vibeke Hjortdal (V)

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark.

Ari Mennander (A)

Department of Cardiothoracic Surgery, Heart Center, Tampere University Hospital, Tampere, Finland.

Shahab Nozohoor (S)

Department of Clinical Sciences, Lund University, Skane University Hospital, Lund, Sweden; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.

Anders Wickbom (A)

Department of Cardiothoracic and Vascular Surgery, Orebro University Hospital, Orebro, Sweden; School of Health and Medicine, Orebro University, Orebro, Sweden.

Igor Zindovic (I)

Department of Clinical Sciences, Lund University, Skane University Hospital, Lund, Sweden; Department of Cardiothoracic Surgery, Lund University, Skåne University Hospital, Lund, Sweden.

Tomas Gudbjartsson (T)

Department of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland.

Anders Jeppsson (A)

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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Classifications MeSH