Microdosimetry at the CATANA 62 MeV proton beam with a sealed miniaturized TEPC.
Microdosimetry
Proton RBE
Proton therapy
TEPC
Journal
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
17
04
2019
revised:
13
06
2019
accepted:
23
06
2019
entrez:
14
9
2019
pubmed:
14
9
2019
medline:
30
1
2020
Statut:
ppublish
Résumé
A new mini-TEPC with cylindrical sensitive volume of 0.9 mm in diameter and height, and with external diameter of 2.7 mm, has been developed to work without gas flow. With such a mini counter we have measured the physical quality of the 62 MeV therapeutic proton beam of CATANA (Catania, Italy). Measurements were performed at six precise positions along the Spread-Out Bragg Peak (SOBP): 1.4, 19.4, 24.6, 29.0, 29.7 and 30.8 mm, corresponding to positions of clinical relevance (entrance, proximal, central, and distal-edge of the SOBP) or of high lineal energy transfer (LET) increment (distal-dose drop off). Without refilling the microdosimeter with new gas, the measurements were repeated at the same positions 4 months later, in order to study the stability of the response in sealed-mode operation. From the microdosimetric spectra the frequency-mean lineal energy y-
Identifiants
pubmed: 31515010
pii: S1120-1797(19)30147-4
doi: 10.1016/j.ejmp.2019.06.011
pii:
doi:
Substances chimiques
Protons
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
114-122Informations de copyright
Copyright © 2019 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.