Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis.


Journal

Diabetes & vascular disease research
ISSN: 1752-8984
Titre abrégé: Diab Vasc Dis Res
Pays: England
ID NLM: 101234011

Informations de publication

Date de publication:
11 2019
Historique:
pubmed: 19 9 2019
medline: 20 2 2020
entrez: 19 9 2019
Statut: ppublish

Résumé

Diabetes contributes directly to the development of cardiovascular aortic valve disease. There is currently no drug therapy available for a dysfunctional valve and this urges the need for additional research to identify distinctive mechanisms of cardiovascular aortic valve disease evolution. The aim of this study was to evaluate changes of valvular aortic lesions induced in a hyperlipemic ApoE

Identifiants

pubmed: 31530180
doi: 10.1177/1479164119874469
pmc: PMC6787765
doi:

Substances chimiques

Blood Glucose 0
Cell Adhesion Molecules 0
Glycated Hemoglobin A 0
HbA(1c) protein, mouse 0
Inflammation Mediators 0
Lipids 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

562-576

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Auteurs

Monica Madalina Tucureanu (MM)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Alexandru Filippi (A)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Nicoleta Alexandru (N)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Cristina Ana Constantinescu (C)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Letitia Ciortan (L)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Razvan Macarie (R)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Mihaela Vadana (M)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Geanina Voicu (G)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Sabina Frunza (S)

Internal Medicine Clinic, Emergency Clinical Hospital, Bucharest, Romania.

Dan Nistor (D)

Clinical Department of Internal Medicine, University of Medicine and Pharmacy of Targu Mures, Targu Mures, Romania.

Agneta Simionescu (A)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.
Clemson University, Clemson, SC, USA.

Dan Teodor Simionescu (DT)

Clemson University, Clemson, SC, USA.

Adriana Georgescu (A)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

Ileana Manduteanu (I)

Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania.

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Classifications MeSH