Zombi: a phylogenetic simulator of trees, genomes and sequences that accounts for dead linages.


Journal

Bioinformatics (Oxford, England)
ISSN: 1367-4811
Titre abrégé: Bioinformatics
Pays: England
ID NLM: 9808944

Informations de publication

Date de publication:
15 02 2020
Historique:
received: 11 04 2019
revised: 09 09 2019
accepted: 26 09 2019
pubmed: 1 10 2019
medline: 18 9 2020
entrez: 1 10 2019
Statut: ppublish

Résumé

Here we present Zombi, a tool to simulate the evolution of species, genomes and sequences in silico, that considers for the first time the evolution of genomes in extinct lineages. It also incorporates various features that have not to date been combined in a single simulator, such as the possibility of generating species trees with a pre-defined variation of speciation and extinction rates through time, simulating explicitly intergenic sequences of variable length and outputting gene tree-species tree reconciliations. Source code and manual are freely available in https://github.com/AADavin/ZOMBI/. Supplementary data are available at Bioinformatics online.

Identifiants

pubmed: 31566657
pii: 5578480
doi: 10.1093/bioinformatics/btz710
pmc: PMC7031779
doi:

Substances chimiques

DNA, Intergenic 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1286-1288

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press.

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Auteurs

Adrián A Davín (AA)

MTA-ELTE Lendület Evolutionary Genomics Research Group, Budapest, Hungary.
Department of Biological Physics, Eötvös Loránd, Budapest, Hungary.

Théo Tricou (T)

Univ Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Évolutive UMR5558, Villeurbanne F-69622, France.

Eric Tannier (E)

Univ Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Évolutive UMR5558, Villeurbanne F-69622, France.
INRIA Grenoble Rhône-Alpes, Montbonnot-Saint-Martin F-38334, France.

Damien M de Vienne (DM)

Univ Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Évolutive UMR5558, Villeurbanne F-69622, France.

Gergely J Szöllősi (GJ)

MTA-ELTE Lendület Evolutionary Genomics Research Group, Budapest, Hungary.
Department of Biological Physics, Eötvös Loránd, Budapest, Hungary.
Evolutionary Systems Research Group, Centre for Ecological Research, Hungarian Academy of Sciences, Tihany H-8237, Hungary.

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Classifications MeSH